Immunological Evaluation of Co‐Assembling a Lipidated Peptide Antigen and Lipophilic Adjuvants: Self‐Adjuvanting Anti‐Breast‐Cancer Vaccine Candidates

2020 ◽  
Vol 132 (40) ◽  
pp. 17858-17864
Author(s):  
Taku Aiga ◽  
Yoshiyuki Manabe ◽  
Keita Ito ◽  
Tsung‐Che Chang ◽  
Kazuya Kabayama ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Vaccine ◽  
Peptide Antigen ◽  
Vaccine Candidates ◽  
Breast Cancer Vaccine ◽  
Immunological Evaluation

Towards Breast Cancer Vaccines, Progress and Challenges

2019 ◽  
Vol 16 (3) ◽  
pp. 251-258 ◽  
Author(s):  
Javad Behravan ◽  
Atefeh Razazan ◽  
Ghazal Behravan
Keyword(s):  
Breast Cancer ◽  
Adverse Effects ◽  
Cancer Vaccine ◽  
Cancer Vaccines ◽  
Weight Control ◽  
The Body ◽  
Phase Iii ◽  
Current Therapy ◽  
Surgical Ablation ◽  
Breast Cancer Vaccine

Breast cancer is the second leading cause of cancer death among women. National cancer institute of the US estimates that one in eight women will be diagnosed with breast cancer during their lifetime. Considering the devastating effects of the disease and the alarming numbers many scientists and research groups have devoted their research to fight breast cancer. Several recommendations are to be considered as preventing measures which include living a healthy lifestyle, regular physical activity, weight control and smoking cessation. Early detection of the disease by annual and regular mammography after the age of 40 is recommended by many healthcare institutions. This would help the diagnosis of the disease at an earlier stage and the start of the treatment before it is spread to other parts of the body. Current therapy for breast cancer includes surgical ablation, radiotherapy and chemotherapy which is often associated with adverse effects and even may lead to a relapse of the disease at a later stage. In order to achieve a long-lasting anticancer response with minimal adverse effects, development of breast cancer vaccines is under investigation by many laboratories. The immune system can be stimulated by a vaccine against breast cancer. This approach has attracted a great enthusiasm in recent years. No breast cancer vaccines have been approved for clinical use today. One breast cancer vaccine (NeuVax) has now completed clinical trial phase III and a few preventive and therapeutic breast cancer vaccines are at different steps of development. We think that with the recent advancements in immunotherapy, a breast cancer vaccine is not far from reach.

scholarly journals Mucosal Delivery of Particulate Breast Cancer Vaccine

2015 ◽  
pp. 171-184
Author(s):  
Lipika Chablani ◽  
Nihal Mulla ◽  
Periasamy Selvaraj ◽  
Martin D'Souza
Keyword(s):  
Breast Cancer ◽  
Cancer Vaccine ◽  
Mucosal Delivery ◽  
Breast Cancer Vaccine

scholarly journals Cyclooxygenase-2 Inhibitor Enhances the Efficacy of a Breast Cancer Vaccine: Role of IDO

2006 ◽  
Vol 177 (4) ◽  
pp. 2391-2402 ◽  
Author(s):  
Gargi D. Basu ◽  
Teresa L. Tinder ◽  
Judy M. Bradley ◽  
Tony Tu ◽  
Christine L. Hattrup ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Vaccine ◽  
Cyclooxygenase 2 ◽  
Breast Cancer Vaccine

Evaluation of a Particulate Breast Cancer Vaccine Delivered via Skin

2019 ◽  
Vol 21 (2) ◽  
Author(s):  
Lipika Chablani ◽  
Suprita A. Tawde ◽  
Archana Akalkotkar ◽  
Martin J. D’Souza
Keyword(s):  
Breast Cancer ◽  
Cancer Vaccine ◽  
Breast Cancer Vaccine

scholarly journals Transcription factor Fos-related antigen 1 is an effective target for a breast cancer vaccine

2003 ◽  
Vol 100 (15) ◽  
pp. 8850-8855 ◽  
Author(s):  
Y. Luo ◽  
H. Zhou ◽  
M. Mizutani ◽  
N. Mizutani ◽  
R. A. Reisfeld ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Transcription Factor ◽  
Cancer Vaccine ◽  
Breast Cancer Vaccine

Su.63. Using Overlapping Synthetic Peptides from Tumor-associated Protein Antigens for Breast Cancer Vaccine Development

2008 ◽  
Vol 127 ◽  
pp. S144-S145
Author(s):  
Saied Mirshahidi ◽  
Victor Kramer ◽  
James Whitney ◽  
Glenn Dranoff ◽  
Karen Anderson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Vaccine ◽  
Synthetic Peptides ◽  
Vaccine Development ◽  
Protein Antigens ◽  
Breast Cancer Vaccine
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