scholarly journals Tailored Palladium Catalysts for Selective Synthesis of Conjugated Enynes by Monocarbonylation of 1,3‐Diynes

2020 ◽  
Vol 132 (23) ◽  
pp. 9117-9125 ◽  
Author(s):  
Jiawang Liu ◽  
Ji Yang ◽  
Carolin Schneider ◽  
Robert Franke ◽  
Ralf Jackstell ◽  
...  
Keyword(s):  
Palladium Catalysts ◽  
Selective Synthesis ◽  
Conjugated Enynes

scholarly journals Tailored Palladium Catalysts for Selective Synthesis of Conjugated Enynes by Monocarbonylation of 1,3‐Diynes

2020 ◽  
Vol 59 (23) ◽  
pp. 9032-9040 ◽  
Author(s):  
Jiawang Liu ◽  
Ji Yang ◽  
Carolin Schneider ◽  
Robert Franke ◽  
Ralf Jackstell ◽  
...  
Keyword(s):  
Palladium Catalysts ◽  
Selective Synthesis ◽  
Conjugated Enynes

Selective synthesis of conjugated enynes from α-arylalkynols using LiCl-Acidic Al2O3 under solvent-free conditions

2002 ◽  
Vol 2002 (8) ◽  
pp. 378-380 ◽  
Author(s):  
Ali Pourjavadi ◽  
Gholam Bagheri Marandi
Keyword(s):  
Solvent Free ◽  
Selective Synthesis ◽  
Solvent Free Conditions ◽  
Conjugated Enynes

α-Arylalkynols were converted into conjugated enynes (in a selective manner under solvent-free conditions) using the LiCl-acidic Al2O3 couple as catalyst and support.

Dehydration-hydration of α-alkynols over zeolite catalyst. Selective synthesis of conjugated enynes and α,β-unsaturated ketones

Tetrahedron ◽  
1996 ◽  
Vol 52 (24) ◽  
pp. 8287-8296 ◽  
Author(s):  
Giovanni Sartori ◽  
Andrea Pastorio ◽  
Raimondo Maggi ◽  
Franca Bigi
Keyword(s):  
Zeolite Catalyst ◽  
Selective Synthesis ◽  
Unsaturated Ketones ◽  
Conjugated Enynes

Selective Synthesis of N-Alkyl Hydroxylamines by Hydrogenation of Nitroalkanes using Supported Palladium Catalysts

ChemSusChem ◽  
2010 ◽  
Vol 3 (10) ◽  
pp. 1166-1168 ◽  
Author(s):  
Yasumasa Takenaka ◽  
Takahiro Kiyosu ◽  
Jun-Chul Choi ◽  
Toshiyasu Sakakura ◽  
Hiroyuki Yasuda
Keyword(s):  
Palladium Catalysts ◽  
Selective Synthesis ◽  
Supported Palladium Catalysts ◽  
Supported Palladium

scholarly journals Copper Hydride-Catalyzed Enantioselective Synthesis of Axially Chiral 1,3-Disubstituted Allenes

2019 ◽  
Author(s):  
Liela Bayeh ◽  
Stephen L. Buchwald
Keyword(s):  
Functional Groups ◽  
Organic Synthesis ◽  
Enantioselective Synthesis ◽  
Hydroxyl Groups ◽  
Copper Hydride ◽  
Selective Synthesis ◽  
Keto Ester ◽  
Axially Chiral ◽  
Conjugated Enynes ◽  
Proton Source

The general enantioselective synthesis of axially chiral disubstituted allenes from prochiral starting materials remains a long-standing challenge in organic synthesis. Here, we report an efficient enantio- and chemoselective copper hydride-catalyzed semi-reduction of conjugated enynes to furnish 1,3-disubstituted allenes using water as the proton source. This protocol is sufficiently mild to accommodate an assortment of functional groups including keto, ester, amino, halo, and hydroxyl groups. Additionally, applications of this method for the selective synthesis of mono-deuterated allenes and chiral 2,5-dihydropyrroles are described.

scholarly journals Copper Hydride-Catalyzed Enantioselective Synthesis of Axially Chiral 1,3-Disubstituted Allenes

2019 ◽  
Author(s):  
Liela Bayeh ◽  
Stephen L. Buchwald
Keyword(s):  
Functional Groups ◽  
Organic Synthesis ◽  
Enantioselective Synthesis ◽  
Hydroxyl Groups ◽  
Copper Hydride ◽  
Selective Synthesis ◽  
Keto Ester ◽  
Axially Chiral ◽  
Conjugated Enynes ◽  
Proton Source

The general enantioselective synthesis of axially chiral disubstituted allenes from prochiral starting materials remains a long-standing challenge in organic synthesis. Here, we report an efficient enantio- and chemoselective copper hydride-catalyzed semi-reduction of conjugated enynes to furnish 1,3-disubstituted allenes using water as the proton source. This protocol is sufficiently mild to accommodate an assortment of functional groups including keto, ester, amino, halo, and hydroxyl groups. Additionally, applications of this method for the selective synthesis of mono-deuterated allenes and chiral 2,5-dihydropyrroles are described.

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