scholarly journals The Effect of β‐Hydrogen Atoms on Iron Speciation in Cross‐Couplings with Simple Iron Salts and Alkyl Grignard Reagents

2019 ◽  
Vol 131 (9) ◽  
pp. 2795-2799 ◽  
Author(s):  
Jeffrey D. Sears ◽  
Salvador B. Muñoz ◽  
Stephanie L. Daifuku ◽  
Ari A. Shaps ◽  
Stephanie H. Carpenter ◽  
...  
Keyword(s):  
Grignard Reagents ◽  
Iron Speciation ◽  
Hydrogen Atoms ◽  
Iron Salts

scholarly journals The Effect of β‐Hydrogen Atoms on Iron Speciation in Cross‐Couplings with Simple Iron Salts and Alkyl Grignard Reagents

2019 ◽  
Vol 58 (9) ◽  
pp. 2769-2773 ◽  
Author(s):  
Jeffrey D. Sears ◽  
Salvador B. Muñoz ◽  
Stephanie L. Daifuku ◽  
Ari A. Shaps ◽  
Stephanie H. Carpenter ◽  
...  
Keyword(s):  
Grignard Reagents ◽  
Iron Speciation ◽  
Hydrogen Atoms ◽  
Iron Salts

scholarly journals Iron-Catalyzed C(sp2)–C(sp3) Cross-Coupling of Aryl Chlorobenzoates with Alkyl Grignard Reagents

Molecules ◽  
2020 ◽  
Vol 25 (1) ◽  
pp. 230 ◽  
Author(s):  
Elwira Bisz ◽  
Michal Szostak
Keyword(s):  
Organic Synthesis ◽  
Nucleophilic Addition ◽  
Functional Group ◽  
High Selectivity ◽  
Cross Coupling ◽  
Environmentally Benign ◽  
Grignard Reagents ◽  
High Importance ◽  
Iron Salts ◽  
The Cross

Aryl benzoates are compounds of high importance in organic synthesis. Herein, we report the iron-catalyzed C(sp2)–C(sp3) Kumada cross-coupling of aryl chlorobenzoates with alkyl Grignard reagents. The method is characterized by the use of environmentally benign and sustainable iron salts for cross-coupling in the catalytic system, employing benign urea ligands in the place of reprotoxic NMP (NMP = N-methyl-2-pyrrolidone). It is notable that high selectivity for the cross-coupling is achieved in the presence of hydrolytically-labile and prone to nucleophilic addition phenolic ester C(acyl)–O bonds. The reaction provides access to alkyl-functionalized aryl benzoates. The examination of various O-coordinating ligands demonstrates the high activity of urea ligands in promoting the cross-coupling versus nucleophilic addition to the ester C(acyl)–O bond. The method showcases the functional group tolerance of iron-catalyzed Kumada cross-couplings.

Grignard Reagents/Iron Salts

2013 ◽  
pp. 261-262
Author(s):  
Tse-Lok Ho ◽  
Mary Fieser ◽  
Louis Fieser
Keyword(s):  
Grignard Reagents ◽  
Iron Salts

Grignard Reagents/Iron Salts

2011 ◽  
pp. 304-305
Author(s):  
Tse-Lok Ho ◽  
Mary Fieser ◽  
Louis Fieser
Keyword(s):  
Grignard Reagents ◽  
Iron Salts

scholarly journals Structural Insights into the Nature of Fe0 and FeI Low-Valent Species Obtained upon the Reduction of Iron Salts by Aryl Grignard Reagents

2017 ◽  
Vol 56 (7) ◽  
pp. 3834-3848 ◽  
Author(s):  
Martin Clémancey ◽  
Thibault Cantat ◽  
Geneviève Blondin ◽  
Jean-Marc Latour ◽  
Pierre Dorlet ◽  
...  
Keyword(s):  
Grignard Reagents ◽  
Iron Salts ◽  
Reduction Of Iron ◽  
Low Valent ◽  
Structural Insights

Remarks on the diffuse interstellar lines

1967 ◽  
Vol 31 ◽  
pp. 91-93 ◽  
Author(s):  
G. Herzberg
Keyword(s):  
Hydrogen Atoms ◽  
Interstellar Gas

It is suggested that the diffuse interstellar lines are produced in the interstellar gas by molecules consisting of a few hydrogen atoms and one other atom, such as CH4+ or NH4. Diffuseness of the lines is assumed to result from predissociation of these molecules.

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