Palladium-Catalyzed Enantioselective Reductive Heck Reactions: Convenient Access to 3,3-Disubstituted 2,3-Dihydrobenzofuran

2018 ◽  
Vol 130 (32) ◽  
pp. 10530-10534 ◽  
Author(s):  
Zhan-Ming Zhang ◽  
Bing Xu ◽  
Yanyan Qian ◽  
Lizuo Wu ◽  
Yuanqi Wu ◽  
...  
Keyword(s):  
Heck Reactions ◽  
Palladium Catalyzed ◽  
Convenient Access

Palladium-Catalyzed Enantioselective Reductive Heck Reactions: Convenient Access to 3,3-Disubstituted 2,3-Dihydrobenzofuran

2018 ◽  
Vol 57 (32) ◽  
pp. 10373-10377 ◽  
Author(s):  
Zhan-Ming Zhang ◽  
Bing Xu ◽  
Yanyan Qian ◽  
Lizuo Wu ◽  
Yuanqi Wu ◽  
...  
Keyword(s):  
Heck Reactions ◽  
Palladium Catalyzed ◽  
Convenient Access

Palladium-catalyzed carbonylative transformation of aryl iodides and sulfonyl chlorides: convenient access to thioesters

2020 ◽  
Vol 7 (6) ◽  
pp. 885-889 ◽  
Author(s):  
Xinxin Qi ◽  
Zhi-Peng Bao ◽  
Xiao-Feng Wu
Keyword(s):  
Sulfonyl Chlorides ◽  
Aryl Iodides ◽  
Palladium Catalyzed ◽  
Convenient Access

A palladium-catalyzed carbonylative transformation of aryl iodides and sulfonyl chlorides to thioesters has been studied.

Palladium-Catalyzed Intermolecular Acylative Heck Reactions with Imides as Acyl Electrophiles

2021 ◽  
Author(s):  
Abhishek A. Kadam ◽  
Tanner L. Metz ◽  
Colton M. David ◽  
Mason T. Koeritz ◽  
Levi M. Stanley
Keyword(s):  
Heck Reactions ◽  
Palladium Catalyzed

Regioselective palladium-catalyzed olefination of coumarinsvia aerobic oxidative Heck reactions

2013 ◽  
Vol 49 (2) ◽  
pp. 196-198 ◽  
Author(s):  
Minsik Min ◽  
Yechan Kim ◽  
Sungwoo Hong
Keyword(s):  
Heck Reactions ◽  
Palladium Catalyzed

Palladium-catalyzed Mizoroki-Heck reactions in water using thermoresponsive polymer micelles

Tetrahedron ◽  
2019 ◽  
Vol 75 (10) ◽  
pp. 1351-1358 ◽  
Author(s):  
Noriyuki Suzuki ◽  
Taiga Takabe ◽  
Yoshiko Yamauchi ◽  
Shun Koyama ◽  
Rina Koike ◽  
...  
Keyword(s):  
Polymer Micelles ◽  
Heck Reactions ◽  
Thermoresponsive Polymer ◽  
Palladium Catalyzed

Synthesis of 2-Pyrrolidinones by Palladium-Catalyzed [3+2] Cycloaddition of Isocyanates

Synlett ◽  
2019 ◽  
Vol 30 (05) ◽  
pp. 581-585 ◽  
Author(s):  
Rolf Breinbauer ◽  
Marko Kljajic ◽  
Thomas Schlatzer
Keyword(s):  
Ring Closure ◽  
Olefin Isomerization ◽  
Stereogenic Centers ◽  
Palladium Catalyzed ◽  
Synthetic Equivalent ◽  
Mechanistic Investigations ◽  
Convenient Access

Pd/DPEphos catalyzes the [3+2] cycloaddition of various alkyl isocyanates with 2-acetoxymethyl-3-allyltrimethylsilane as a synthetic equivalent of trimethylenemethane (TMM). Taking advantage of 2-acetoxymethyl-3-allyltrimethylsilane acting both as nucleophile as well as electrophile this reaction gives a convenient access to 5-ring lactams with an exocyclic alkene moiety. The formation of the β,γ-unsaturated 2-pyrrolidinones occurs without olefin isomerization and without epimerization of the stereogenic centers. Mechanistic investigations suggest an initial N-allylation of the isocyanate followed by nucleophilic ring closure furnishing the desired 2-pyrrolidinones.

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