scholarly journals Enantioselective Synthesis of Vicinal All-Carbon Quaternary Centers via Iridium-Catalyzed Allylic Alkylation

2018 ◽  
Vol 130 (28) ◽  
pp. 8800-8803 ◽  
Author(s):  
J. Caleb Hethcox ◽  
Samantha E. Shockley ◽  
Brian M. Stoltz
Keyword(s):  
Enantioselective Synthesis ◽  
Allylic Alkylation ◽  
Quaternary Centers

Novel Chiral Ligands for Palladium-catalyzed Asymmetric Allylic Alkylation/ Asymmetric Tsuji-Trost Reaction: A Review

2019 ◽  
Vol 23 (11) ◽  
pp. 1168-1213 ◽  
Author(s):  
Samar Noreen ◽  
Ameer Fawad Zahoor ◽  
Sajjad Ahmad ◽  
Irum Shahzadi ◽  
Ali Irfan ◽  
...  
Keyword(s):  
Asymmetric Catalysis ◽  
Enantioselective Synthesis ◽  
Chiral Ligands ◽  
Allylic Alkylation ◽  
Research Groups ◽  
Asymmetric Allylic Alkylation ◽  
Catalytic Potential ◽  
Long Time ◽  
Palladium Catalyzed ◽  
Alkylation Reactions

Background: Asymmetric catalysis holds a prestigious role in organic syntheses since a long time and chiral inductors such as ligands have been used to achieve the utmost desired results at this pitch. The asymmetric version of Tsuji-Trost allylation has played a crucial role in enantioselective synthesis. Various chiral ligands have been known for Pdcatalyzed Asymmetric Allylic Alkylation (AAA) reactions and exhibited excellent catalytic potential. The use of chiral ligands as asymmetric inductors has widened the scope of Tsuji-Trost allylic alkylation reactions. Conclusion: Therefore, in this review article, a variety of chiral inductors or ligands have been focused for palladium catalyzed asymmetric allylic alkylation (Tsuji-Trost allylation) and in this regard, recently reported literature (2013-2017) has been described. The use of ligands causes the induction of enantiodiscrimination to the allylated products, therefore, the syntheses of various kinds of ligands have been targeted by many research groups to employ in Pd-catalyzed AAA reactions.

Organocatalytic Asymmetric C(sp 2 )−H Allylic Alkylation: Enantioselective Synthesis of Tetrasubstituted Allenoates

2020 ◽  
Vol 59 (45) ◽  
pp. 19820-19824
Author(s):  
Yimin Hu ◽  
Wangyu Shi ◽  
Bing Zheng ◽  
Jianning Liao ◽  
Wei Wang ◽  
...  
Keyword(s):  
Enantioselective Synthesis ◽  
Allylic Alkylation
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