Synergistic Rhodium/Phosphoric Acid Catalysis for the Enantioselective Addition of Oxonium Ylides to ortho -Quinone Methides

2016 ◽  
Vol 128 (7) ◽  
pp. 2438-2442 ◽  
Author(s):  
Santosh Kumar Alamsetti ◽  
Matthias Spanka ◽  
Christoph Schneider
Keyword(s):  
Phosphoric Acid ◽  
Acid Catalysis ◽  
Quinone Methides ◽  
Oxonium Ylides ◽  
Enantioselective Addition

VAPOL phosphoric acid catalysis: the highly enantioselective addition of imides to imines

2007 ◽  
pp. 4477 ◽  
Author(s):  
Yuxue Liang ◽  
Emily B. Rowland ◽  
Gerald B. Rowland ◽  
Jason A. Perman ◽  
Jon C. Antilla
Keyword(s):  
Phosphoric Acid ◽  
Acid Catalysis ◽  
Enantioselective Addition

ChemInform Abstract: VAPOL Phosphoric Acid Catalysis: The Highly Enantioselective Addition of Imides to Imines.

ChemInform ◽  
2008 ◽  
Vol 39 (11) ◽  
Author(s):  
Yuxue Liang ◽  
Emily B. Rowland ◽  
Gerald B. Rowland ◽  
Jason A. Perman ◽  
Jon C. Antilla
Keyword(s):  
Phosphoric Acid ◽  
Acid Catalysis ◽  
Enantioselective Addition

Practical catalytic enantioselective synthesis of 2,3-dihydroquin-azolinones by chiral brønsted acid catalysis

2021 ◽  
Author(s):  
Yongbiao Guo ◽  
Zhenhua Gao ◽  
Junchen Li ◽  
Xiaojing Bi ◽  
Enxue Shi ◽  
...  
Keyword(s):  
Phosphoric Acid ◽  
Acid Catalysis ◽  
Enantioselective Synthesis ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Brönsted Acid ◽  
Chiral Bronsted Acid ◽  
Bronsted Acid Catalysis

An efficient, practical and scalable protocol to prepare chiral 2,3-dihydroquinazolinones was developed under catalysis of spirocyclic SPINOL-phosphoric acid.

The Highly Enantioselective Addition of Indoles toN-Acyl Imines with Use of a Chiral Phosphoric Acid Catalyst

2007 ◽  
Vol 9 (14) ◽  
pp. 2609-2611 ◽  
Author(s):  
Gerald B. Rowland ◽  
Emily B. Rowland ◽  
Yuxue Liang ◽  
Jason A. Perman ◽  
Jon C. Antilla
Keyword(s):  
Phosphoric Acid ◽  
Acid Catalyst ◽  
Chiral Phosphoric Acid ◽  
Enantioselective Addition

scholarly journals Organocatalytic Asymmetric [2 + 4] Cycloadditions of 3-Vinylindoles with ortho-Quinone Methides

Molecules ◽  
2021 ◽  
Vol 26 (21) ◽  
pp. 6751
Author(s):  
Si-Jia Liu ◽  
Man-Su Tu ◽  
Kai-Yue Liu ◽  
Jia-Yi Chen ◽  
Shao-Fei Ni ◽  
...  
Keyword(s):  
Phosphoric Acid ◽  
Structural Diversity ◽  
Quinone Methides ◽  
Chiral Phosphoric Acid ◽  
Catalytic Asymmetric ◽  
High Yields ◽  
Asymmetric Cycloadditions

Catalytic asymmetric [2 + 4] cycloadditions of 3-vinylindoles with ortho-quinone methides and their precursors were carried out in the presence of chiral phosphoric acid to afford a series of indole-containing chroman derivatives with structural diversity in overall high yields (up to 98%), good diastereoselectivities (up to 93:7 dr) and moderate to excellent enantioselectivities (up to 98% ee). This approach not only enriches the chemistry of catalytic asymmetric cycloadditions involving 3-vinylindoles but is also useful for synthesizing chiral chroman derivatives.

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