Kinetic Resolution of Azomethine Imines by Brønsted Acid Catalyzed Enantioselective Reduction

2015 ◽  
Vol 127 (51) ◽  
pp. 15736-15739 ◽  
Author(s):  
Amanda Bongers ◽  
Patrick J. Moon ◽  
André M. Beauchemin
Keyword(s):  
Kinetic Resolution ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Enantioselective Reduction ◽  
Brönsted Acid ◽  
Acid Catalyzed ◽  
Azomethine Imines

Brønsted Acid-catalyzed Dynamic Kinetic Resolution of in situ Formed Acyclic N,O-hemiaminals: Cascade Synthesis of Chiral Cyclic N,O-aminals

2021 ◽  
Author(s):  
Xue-Jiao Lv ◽  
Yong-Chao Ming ◽  
Hui-Chun Wu ◽  
Yankai Liu
Keyword(s):  
Kinetic Resolution ◽  
Michael Reaction ◽  
Amide Group ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Dynamic Kinetic Resolution ◽  
Brönsted Acid ◽  
Acid Catalyzed

A Brønsted acid-catalyzed cascade acyclic N,O-hemiaminal formation/oxa-Michael reaction is developed for the synthesis of cis-2,6-disubstituted tetrahydropyrans bearing an exo amide group, that is, cyclic N,O-aminals. By using TsOH, various different...

Facile Synthesis of Versatile Enantioenriched α-Substituted Hydroxy Esters through a Brønsted Acid Catalyzed Kinetic Resolution

2013 ◽  
Vol 15 (6) ◽  
pp. 1266-1269 ◽  
Author(s):  
Ghassan Qabaja ◽  
Jennifer E. Wilent ◽  
Amanda R. Benavides ◽  
George E. Bullard ◽  
Kimberly S. Petersen
Keyword(s):  
Kinetic Resolution ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Facile Synthesis ◽  
Brönsted Acid ◽  
Hydroxy Esters ◽  
Acid Catalyzed

Brønsted acid-catalyzed stereoselective [4+3] cycloadditions of ortho-hydroxybenzyl alcohols with N,N′-cyclic azomethine imines

2017 ◽  
Vol 53 (18) ◽  
pp. 2768-2771 ◽  
Author(s):  
Guang-Jian Mei ◽  
Zi-Qi Zhu ◽  
Jia-Jia Zhao ◽  
Chen-Yu Bian ◽  
Jie Chen ◽  
...  
Keyword(s):  
Bronsted Acid ◽  
Brønsted Acid ◽  
Brönsted Acid ◽  
Acid Catalyzed ◽  
Azomethine Imines

The first [4+3] cycloaddition of ortho-hydroxybenzyl alcohols has been established to construct biologically important seven-membered heterocyclic scaffolds in good yields and excellent diastereoselectivities (up to 92% yield, most >95 : 5 dr).

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