A Plausible Simultaneous Synthesis of Amino Acids and Simple Peptides on the Primordial Earth

2014 ◽  
Vol 126 (31) ◽  
pp. 8270-8274 ◽  
Author(s):  
Eric T. Parker ◽  
Manshui Zhou ◽  
Aaron S. Burton ◽  
Daniel P. Glavin ◽  
Jason P. Dworkin ◽  
...  
Keyword(s):  
Amino Acids ◽  
Simultaneous Synthesis ◽  
Primordial Earth

scholarly journals Rücktitelbild: A Plausible Simultaneous Synthesis of Amino Acids and Simple Peptides on the Primordial Earth (Angew. Chem. 31/2014)

2014 ◽  
Vol 126 (31) ◽  
pp. 8392-8392
Author(s):  
Eric T. Parker ◽  
Manshui Zhou ◽  
Aaron S. Burton ◽  
Daniel P. Glavin ◽  
Jason P. Dworkin ◽  
...  
Keyword(s):  
Amino Acids ◽  
Simultaneous Synthesis ◽  
Primordial Earth

A Plausible Simultaneous Synthesis of Amino Acids and Simple Peptides on the Primordial Earth

2014 ◽  
Vol 53 (31) ◽  
pp. 8132-8136 ◽  
Author(s):  
Eric T. Parker ◽  
Manshui Zhou ◽  
Aaron S. Burton ◽  
Daniel P. Glavin ◽  
Jason P. Dworkin ◽  
...  
Keyword(s):  
Amino Acids ◽  
Simultaneous Synthesis ◽  
Primordial Earth

scholarly journals Back Cover: A Plausible Simultaneous Synthesis of Amino Acids and Simple Peptides on the Primordial Earth (Angew. Chem. Int. Ed. 31/2014)

2014 ◽  
Vol 53 (31) ◽  
pp. 8252-8252 ◽  
Author(s):  
Eric T. Parker ◽  
Manshui Zhou ◽  
Aaron S. Burton ◽  
Daniel P. Glavin ◽  
Jason P. Dworkin ◽  
...  
Keyword(s):  
Amino Acids ◽  
Back Cover ◽  
Simultaneous Synthesis ◽  
Primordial Earth

Simultaneous synthesis of enantiomerically pure (S)-amino acids and (R)-amines using coupled transaminase reactions

2003 ◽  
Vol 81 (7) ◽  
pp. 783-789 ◽  
Author(s):  
Byung-Kwan Cho ◽  
Ho Jung Cho ◽  
Sung-Hee Park ◽  
Hyungdon Yun ◽  
Byung-Gee Kim
Keyword(s):  
Amino Acids ◽  
Enantiomerically Pure ◽  
Simultaneous Synthesis

Amino acids on the rampant primordial Earth: Electric discharges and the hot salty ocean

2006 ◽  
Vol 10 (1) ◽  
pp. 3-7 ◽  
Author(s):  
Kristof Plankensteiner ◽  
Hannes Reiner ◽  
Bernd M. Rode
Keyword(s):  
Amino Acids ◽  
Electric Discharges ◽  
Primordial Earth

scholarly journals Formation of nucleobases in a Miller–Urey reducing atmosphere

2017 ◽  
Vol 114 (17) ◽  
pp. 4306-4311 ◽  
Author(s):  
Martin Ferus ◽  
Fabio Pietrucci ◽  
Antonino Marco Saitta ◽  
Antonín Knížek ◽  
Petr Kubelík ◽  
...  
Keyword(s):  
Amino Acids ◽  
Electric Discharge ◽  
State Of The Art ◽  
Gas Mixture ◽  
Biologically Relevant ◽  
Reducing Atmosphere ◽  
Biologically Relevant Molecules ◽  
Impact Simulations ◽  
Primordial Earth ◽  
Theoretical Results

The Miller–Urey experiments pioneered modern research on the molecular origins of life, but their actual relevance in this field was later questioned because the gas mixture used in their research is considered too reducing with respect to the most accepted hypotheses for the conditions on primordial Earth. In particular, the production of only amino acids has been taken as evidence of the limited relevance of the results. Here, we report an experimental work, combined with state-of-the-art computational methods, in which both electric discharge and laser-driven plasma impact simulations were carried out in a reducing atmosphere containing NH3 + CO. We show that RNA nucleobases are synthesized in these experiments, strongly supporting the possibility of the emergence of biologically relevant molecules in a reducing atmosphere. The reconstructed synthetic pathways indicate that small radicals and formamide play a crucial role, in agreement with a number of recent experimental and theoretical results.

Homochirality as the Signature of Extra-Terrestrial Life

1997 ◽  
Vol 161 ◽  
pp. 505-510
Author(s):  
Alexandra J. MacDermott ◽  
Laurence D. Barron ◽  
Andrè Brack ◽  
Thomas Buhse ◽  
John R. Cronin ◽  
...  
Keyword(s):  
Amino Acids ◽  
Protein Synthesis ◽  
Optical Rotation ◽  
Physical Origin ◽  
Natural Choice ◽  
Rosetta Mission ◽  
Terrestrial Life ◽  
Subsurface Layers ◽  
Solar System Bodies ◽  
Origin Of Homochirality

AbstractThe most characteristic hallmark of life is its homochirality: all biomolecules are usually of one hand, e.g. on Earth life uses only L-amino acids for protein synthesis and not their D mirror images. We therefore suggest that a search for extra-terrestrial life can be approached as a Search for Extra- Terrestrial Homochirality (SETH). The natural choice for a SETH instrument is optical rotation, and we describe a novel miniaturized space polarimeter, called the SETH Cigar, which could be used to detect optical rotation as the homochiral signature of life on other planets. Moving parts are avoided by replacing the normal rotating polarizer by multiple fixed polarizers at different angles as in the eye of the bee. We believe that homochirality may be found in the subsurface layers on Mars as a relic of extinct life, and on other solar system bodies as a sign of advanced pre-biotic chemistry. We discuss the chiral GC-MS planned for the Roland lander of the Rosetta mission to a comet and conclude with theories of the physical origin of homochirality.

Hydrogen Cyanide Polymers from the Impact of Comet P/Shoemaker-Levy 9 on Jupiter

1997 ◽  
Vol 161 ◽  
pp. 179-187
Author(s):  
Clifford N. Matthews ◽  
Rose A. Pesce-Rodriguez ◽  
Shirley A. Liebman
Keyword(s):  
Amino Acids ◽  
Solar System ◽  
Hydrogen Cyanide ◽  
Nitrogen Heterocycles ◽  
Laboratory Studies ◽  
Heterogeneous Solids ◽  
The Many ◽  
Comet Halley ◽  
The Impact ◽  
By Products

AbstractHydrogen cyanide polymers – heterogeneous solids ranging in color from yellow to orange to brown to black – may be among the organic macromolecules most readily formed within the Solar System. The non-volatile black crust of comet Halley, for example, as well as the extensive orangebrown streaks in the atmosphere of Jupiter, might consist largely of such polymers synthesized from HCN formed by photolysis of methane and ammonia, the color observed depending on the concentration of HCN involved. Laboratory studies of these ubiquitous compounds point to the presence of polyamidine structures synthesized directly from hydrogen cyanide. These would be converted by water to polypeptides which can be further hydrolyzed to α-amino acids. Black polymers and multimers with conjugated ladder structures derived from HCN could also be formed and might well be the source of the many nitrogen heterocycles, adenine included, observed after pyrolysis. The dark brown color arising from the impacts of comet P/Shoemaker-Levy 9 on Jupiter might therefore be mainly caused by the presence of HCN polymers, whether originally present, deposited by the impactor or synthesized directly from HCN. Spectroscopic detection of these predicted macromolecules and their hydrolytic and pyrolytic by-products would strengthen significantly the hypothesis that cyanide polymerization is a preferred pathway for prebiotic and extraterrestrial chemistry.

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