Direct Transformation of Secondary Amides into Secondary Amines: Triflic Anhydride Activated Reductive Alkylation

2012 ◽  
Vol 124 (33) ◽  
pp. 8439-8442 ◽  
Author(s):  
Kai-Jiong Xiao ◽  
Ai-E Wang ◽  
Pei-Qiang Huang
Keyword(s):  
Secondary Amines ◽  
Reductive Alkylation ◽  
Direct Transformation ◽  
Secondary Amides

A Reductive Alkylation Procedure Applicable to Both Solution- and Solid-Phase Syntheses of Secondary Amines

1996 ◽  
Vol 61 (19) ◽  
pp. 6720-6722 ◽  
Author(s):  
Anna K. Szardenings ◽  
Timothy S. Burkoth ◽  
Gary C. Look ◽  
David A. Campbell
Keyword(s):  
Solid Phase ◽  
Secondary Amines ◽  
Reductive Alkylation

scholarly journals Catalytic reductive N-alkylation of amines using carboxylic acids

2016 ◽  
Vol 52 (9) ◽  
pp. 1855-1858 ◽  
Author(s):  
Keith G. Andrews ◽  
Declan M. Summers ◽  
Liam J. Donnelly ◽  
Ross M. Denton
Keyword(s):  
Carboxylic Acids ◽  
Secondary Amines ◽  
Alkylation Reaction ◽  
Reductive Alkylation

We report a catalytic reductive alkylation reaction of primary or secondary amines with carboxylic acids.

Catalyst-Free One-Pot Reductive Alkylation of Primary and Secondary Amines and N,N-Dimethylation of Amino Acids Using Sodium Borohydride in 2,2,2-Trifluoroethanol

Synthesis ◽  
2010 ◽  
Vol 2011 (03) ◽  
pp. 490-496 ◽  
Author(s):  
Mahmood Tajbakhsh ◽  
Rahman Hosseinzadeh ◽  
Heshmatollah Alinezhad ◽  
Somayeh Ghahari ◽  
Akbar Heydari ◽  
...  
Keyword(s):  
Amino Acids ◽  
Sodium Borohydride ◽  
Secondary Amines ◽  
Reductive Alkylation ◽  
One Pot ◽  
Catalyst Free ◽  
Primary And Secondary Amines

Synthesis of 7-substituted 3-β-D-ribofuranosyl-3H-imidazo[2,1-i]purines

2011 ◽  
Vol 76 (8) ◽  
pp. 1043-1054 ◽  
Author(s):  
Tuomas Karskela ◽  
Karel D. Klika ◽  
Harri Lönnberg
Keyword(s):  
Secondary Amines ◽  
Formyl Group ◽  
Reductive Alkylation

A method for the synthesis of 7-substituted 3-β-D-ribofuranosyl-3H-imidazo[2,1-i]purines has been devised whereby compounds were prepared in a few steps from a common intermediate, 3-(2′,3′-O-isopropylidene-β-D-ribofuranosyl)-3H-imidazo[2,1-i]purine-7-carbaldehyde, obtained from the reaction of 2′,3′-O-isopropylideneadenosine with bromomalonaldehyde. The formyl group of the carbaldehyde was subsequently reductively aminated and the resulting secondary amines were then further derivatized either by acylation, lactamization or reductive alkylation.

Indium-catalyzed reduction of secondary amides with a hydrosiloxane leading to secondary amines

2015 ◽  
Vol 56 (46) ◽  
pp. 6448-6451 ◽  
Author(s):  
Norio Sakai ◽  
Masashi Takeoka ◽  
Takayuki Kumaki ◽  
Hirotaka Asano ◽  
Takeo Konakahara ◽  
...  
Keyword(s):  
Secondary Amines ◽  
Secondary Amides
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