Aptamer-Directed Self-Assembly of Protein Arrays on a DNA Nanostructure

2005 ◽  
Vol 117 (28) ◽  
pp. 4407-4412 ◽  
Author(s):  
Yan Liu ◽  
Chenxiang Lin ◽  
Hanying Li ◽  
Hao Yan
2005 ◽  
Vol 44 (28) ◽  
pp. 4333-4338 ◽  
Author(s):  
Yan Liu ◽  
Chenxiang Lin ◽  
Hanying Li ◽  
Hao Yan

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Chensheng Zhou ◽  
Heng Luo ◽  
Xiaolu Feng ◽  
Xingwang Li ◽  
Jie Zhu ◽  
...  

DNA self-assembly is a nanotechnology that folds DNA into desired shapes. Self-assembled DNA nanostructures, also known as origami, are increasingly valuable in nanomaterial and biosensing applications. Two ways to use DNA nanostructures in medicine are to form nanoarrays, and to work as vehicles in drug delivery. The DNA nanostructures perform well as a biomaterial in these areas because they have spatially addressable and size controllable properties. However, manually designing complementary DNA sequences for self-assembly is a technically demanding and time consuming task, which makes it advantageous for computers to do this job instead. We have developed a web server, FOLDNA, which can automatically design 2D self-assembled DNA nanostructures according to custom pictures and scaffold sequences provided by the users. It is the first web server to provide an entirely automatic design of self-assembled DNA nanostructure, and it takes merely a second to generate comprehensive information for molecular experiments including: scaffold DNA pathways, staple DNA directions, and staple DNA sequences. This program could save as much as several hours in the designing step for each DNA nanostructure. We randomly selected some shapes and corresponding outputs from our server and validated its performance in molecular experiments.


BioTechniques ◽  
2014 ◽  
Vol 56 (4) ◽  
Author(s):  
Takanobu Tsutsumi ◽  
Takeshi Asakawa ◽  
Akemi Kanegami ◽  
Takao Okada ◽  
Tomoko Tahira ◽  
...  

Nanoscale ◽  
2014 ◽  
Vol 6 (9) ◽  
pp. 4486-4490 ◽  
Author(s):  
Anirban Samanta ◽  
Zhengtao Deng ◽  
Yan Liu

DNA conjugation of infrared emitting hydrophilic QDs and their organization site specifically onto DNA nanostructure.


2011 ◽  
Vol 12 (10) ◽  
pp. 3400-3405 ◽  
Author(s):  
Niculina D. Bogdan ◽  
Mihaela Matache ◽  
Gheorghe-Doru Roiban ◽  
Cristian Dobrotă ◽  
Veronika M. Meier ◽  
...  

2019 ◽  
Vol 11 (6) ◽  
pp. 510-520 ◽  
Author(s):  
Leopold N. Green ◽  
Hari K. K. Subramanian ◽  
Vahid Mardanlou ◽  
Jongmin Kim ◽  
Rizal F. Hariadi ◽  
...  

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