Deep Brain Stimulation for Chronic Cluster Headache: Meta‐Analysis of Individual Patient Data

2020 ◽  
Vol 88 (5) ◽  
pp. 956-969
Author(s):  
Andreas Nowacki ◽  
Martin Schober ◽  
Lydia Nader ◽  
Assel Saryyeva ◽  
Thuy‐Anh Khoa Nguyen ◽  
...  
2020 ◽  
Vol 267 (6) ◽  
pp. 1780-1792
Author(s):  
Xing Hua ◽  
Bohan Zhang ◽  
Zhicheng Zheng ◽  
Houyou Fan ◽  
Linfeng Luo ◽  
...  

2019 ◽  
Vol 266 (11) ◽  
pp. 2646-2656 ◽  
Author(s):  
Xin Wang ◽  
Zhibin Zhang ◽  
Zhiqi Mao ◽  
Xinguang Yu

2003 ◽  
Vol 6 (3) ◽  
pp. 206-206
Author(s):  
Angelo Franzini ◽  
Giovanni Broggi ◽  
Gennaro Bussone ◽  
Paolo Ferroli ◽  
Massimo Leone ◽  
...  

Neurosurgery ◽  
2018 ◽  
Vol 65 (CN_suppl_1) ◽  
pp. 115-115
Author(s):  
Nilson N. Mendes Neto ◽  
Jessika Thais da Silva Maia ◽  
Juliano Jose da Silva ◽  
Sergio Adrian Fernandes Dantas ◽  
Marcelo Rodrigues Zacarkim ◽  
...  

2018 ◽  
Vol 22 (4) ◽  
pp. 388-397 ◽  
Author(s):  
Daivik B. Vyas ◽  
Allen L. Ho ◽  
David Y. Dadey ◽  
Arjun V. Pendharkar ◽  
Eric S. Sussman ◽  
...  

Cephalalgia ◽  
2008 ◽  
Vol 28 (3) ◽  
pp. 285-295 ◽  
Author(s):  
T Bartsch ◽  
MO Pinsker ◽  
D Rasche ◽  
T Kinfe ◽  
F Hertel ◽  
...  

Deep brain stimulation (DBS) of the posterior hypothalamus was found to be effective in the treatment of drug-resistant chronic cluster headache. We report the results of a multicentre case series of six patients with chronic cluster headache in whom a DBS in the posterior hypothalamus was performed. Electrodes were implanted stereotactically in the ipsilateral posterior hypothalamus according to published coordinates 2 mm lateral, 3 mm posterior and 5 mm inferior referenced to the mid-AC-PC line. Microelectrode recordings at the target revealed single unit activity with a mean discharge rate of 17 Hz (range 13-35 Hz, n = 4). Out of six patients, four showed a profound decrease of their attack frequency and pain intensity on the visual analogue scale during the first 6 months. Of these, one patient was attack free for 6 months under neurostimulation before returning to the baseline which led to abortion of the DBS. Two patients had experienced only a marginal, non-significant decrease within the first weeks under neurostimulation before returning to their former attack frequency. After a mean follow-up of 17 months, three patients are almost completely attack free, whereas three patients can be considered as treatment failures. The stimulation was well tolerated and stimulation-related side-effects were not observed on long term. DBS of the posterior inferior hypothalamus is an effective therapeutic option in a subset of patients. Future controlled multi-centre trials will need to confirm this open-label experience and should help to better define predictive factors for non-responders.


Cephalalgia ◽  
2012 ◽  
Vol 33 (2) ◽  
pp. 136-138 ◽  
Author(s):  
Giuseppe Messina ◽  
Michele Rizzi ◽  
Roberto Cordella ◽  
Augusto Caraceni ◽  
Ernesto Zecca ◽  
...  

Introduction Deep brain stimulation (DBS) of the posterior hypothalamus (pHyp) has been reported as an effective treatment for primary, drug-refractory and chronic cluster headache (CCH). We here describe the use of such a procedure for the treatment of secondary CCH due to a neoplasm affecting the soft tissues of the right hemiface. Methods A 27-year-old man affected by infiltrating angiomyolipoma of the right hemiface who subsequently developed drug refractory homolateral CCH underwent DBS of the right pHyp region at the Fondazione IRCCS Istituto Nazionale Neurologico Carlo Besta. Results After surgery, the patient presented a significant reduction in frequency of pain bouts. However, because of a subsequent infection, the entire system was removed. After re-implantation of the system, successful outcome was observed at 2 years follow-up. Discussion This brief report shows the feasibility of pHyp DBS in secondary drug-refractory CCH syndromes; future reports are needed in order to confirm our positive result.


Sign in / Sign up

Export Citation Format

Share Document