Plasminogen activator inhibitor‐1 augments damage by impairing fibrinolysis after traumatic brain injury

Eva‐Verena Griemert; Susanne M. Schwarzmaier; Regina Hummel; Christina Gölz; Dong Yang; Winfried Neuhaus; Malgorzata Burek; Carola Y. Förster; Ivan Petkovic; Raimund Trabold; Nikolaus Plesnila; Kristin Engelhard; Michael K. Schäfer; Serge C. Thal

doi:10.1002/ana.25458

Plasminogen activator inhibitor‐1 augments damage by impairing fibrinolysis after traumatic brain injury

Annals of Neurology ◽

10.1002/ana.25458 ◽

2019 ◽

Vol 85 (5) ◽

pp. 667-680 ◽

Cited By ~ 8

Author(s):

Eva‐Verena Griemert ◽

Susanne M. Schwarzmaier ◽

Regina Hummel ◽

Christina Gölz ◽

Dong Yang ◽

...

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Plasminogen Activator Inhibitor 1 ◽

Activator Inhibitor

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Neuroprotective Effect of Plasminogen Activator Inhibitor-1 Antagonist in the Rat Model of Mild Traumatic Brain Injury

Inflammation ◽

10.1007/s10753-021-01520-0 ◽

2021 ◽

Author(s):

Pınar Kuru Bektaşoğlu ◽

Türkan Koyuncuoğlu ◽

Selin Akbulut ◽

Dilek Akakın ◽

İrem Peker Eyüboğlu ◽

...

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Plasminogen Activator ◽

Mild Traumatic Brain Injury ◽

Rat Model ◽

Neuroprotective Effect ◽

Plasminogen Activator Inhibitor ◽

Plasminogen Activator Inhibitor 1 ◽

Activator Inhibitor

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Changes of general cerebral symptoms in patients with traumatic brain injury and their dependence on the -675 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene

Pathologia ◽

10.14739/2310-1237.2016.1.71577 ◽

2016 ◽

Vol 0 (1) ◽

Author(s):

O. O. Potapov ◽

O. P. Kmyta

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Plasminogen Activator Inhibitor 1 ◽

Activator Inhibitor

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Hemostatic profile changes in patients with traumatic brain injury with regard to the genotypes of -675 4G/5G polymorphism of plasminogen activator inhibitor-1 gene

Zaporozhye Medical Journal ◽

10.14739/2310-1210.2016.2.69233 ◽

2016 ◽

Vol 0 (2) ◽

Author(s):

O. O. Potapov ◽

O. P. Kmyta ◽

N. S. Shekera ◽

K. A. Pabot

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Plasminogen Activator Inhibitor 1 ◽

Profile Changes ◽

Activator Inhibitor

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The procoagulant molecule plasminogen activator inhibitor-1 is associated with injury severity and shock in patients with and without traumatic brain injury

Journal of Trauma and Acute Care Surgery ◽

10.1097/ta.0000000000002040 ◽

2018 ◽

Vol 85 (5) ◽

pp. 888-893 ◽

Cited By ~ 5

Author(s):

Mary Condron ◽

Susan Rowell ◽

Elizabeth Dewey ◽

Taylor Anderson ◽

Lelani Lealiiee ◽

...

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Plasminogen Activator ◽

Injury Severity ◽

Plasminogen Activator Inhibitor ◽

Plasminogen Activator Inhibitor 1 ◽

Activator Inhibitor

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Combination therapy with glucagon and a novel plasminogen activator inhibitor-1-derived peptide enhances protection against impaired cerebrovasodilation during hypotension after traumatic brain injury through inhibition of ERK and JNK MAPK

Neurological Research ◽

10.1179/1743132812y.0000000039 ◽

2012 ◽

Vol 34 (6) ◽

pp. 530-537 ◽

Cited By ~ 9

Author(s):

William M Armstead ◽

John Riley ◽

Douglas B Cines ◽

Abd Al-Roof Higazi

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Combination Therapy ◽

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Plasminogen Activator Inhibitor 1 ◽

Activator Inhibitor

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Dependence of plasminogen activator inhibitor-1 level on -675 4G/5G polymorphism in PAI-1 gene in patients with traumatic brain injury

Ukrainian Neurosurgical Journal ◽

10.25305/unj.46604 ◽

2014 ◽

Vol 0 (4) ◽

pp. 61-64

Author(s):

Oleksandr Potapov Jr ◽

Oleksii Kmyta

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Plasminogen Activator Inhibitor 1 ◽

Activator Inhibitor ◽

Pai 1

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Taming Neonatal Hypoxic–Ischemic Brain Injury by Intranasal Delivery of Plasminogen Activator Inhibitor-1

Stroke ◽

10.1161/strokeaha.113.001233 ◽

2013 ◽

Vol 44 (9) ◽

pp. 2623-2627 ◽

Cited By ~ 11

Author(s):

Dianer Yang ◽

Yu-Yo Sun ◽

Xiaoyi Lin ◽

Jessica M. Baumann ◽

Mark Warnock ◽

...

Keyword(s):

Brain Injury ◽

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Ischemic Brain Injury ◽

Intranasal Delivery ◽

Plasminogen Activator Inhibitor 1 ◽

Ischemic Brain ◽

Hypoxic Ischemic Brain Injury ◽

Activator Inhibitor

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Therapeutic Administration of Plasminogen Activator Inhibitor-1 Prevents Hypoxic-Ischemic Brain Injury in Newborns

Journal of Neuroscience ◽

10.1523/jneurosci.1117-09.2009 ◽

2009 ◽

Vol 29 (27) ◽

pp. 8669-8674 ◽

Cited By ~ 29

Author(s):

D. Yang ◽

N. Nemkul ◽

A. Shereen ◽

A. Jone ◽

R. S. Dunn ◽

...

Keyword(s):

Brain Injury ◽

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Ischemic Brain Injury ◽

Plasminogen Activator Inhibitor 1 ◽

Ischemic Brain ◽

Hypoxic Ischemic Brain Injury ◽

Therapeutic Administration ◽

Activator Inhibitor

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Plasminogen Activator Inhibitor Type 1: A Possible Novel Biomarker of Late Pituitary Dysfunction after Mild Traumatic Brain Injury

Journal of Neurotrauma ◽

10.1089/neu.2017.5198 ◽

2017 ◽

Vol 34 (23) ◽

pp. 3238-3244 ◽

Cited By ~ 2

Author(s):

Istvan Frendl ◽

Monika Katko ◽

Erika Galgoczi ◽

Judit Boda ◽

Noemi Zsiros ◽

...

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Plasminogen Activator ◽

Mild Traumatic Brain Injury ◽

Plasminogen Activator Inhibitor ◽

Pituitary Dysfunction ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Activator Inhibitor

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Plasminogen Activator Inhibitor-1 Mitigates Brain Injury in a Rat Model of Infection-Sensitized Neonatal Hypoxia-Ischemia

Cerebral Cortex ◽

10.1093/cercor/bhs115 ◽

2012 ◽

Vol 23 (5) ◽

pp. 1218-1229 ◽

Cited By ~ 19

Author(s):

D. Yang ◽

Y.-Y. Sun ◽

N. Nemkul ◽

J. M. Baumann ◽

A. Shereen ◽

...

Keyword(s):

Brain Injury ◽

Plasminogen Activator ◽

Rat Model ◽

Plasminogen Activator Inhibitor ◽

Plasminogen Activator Inhibitor 1 ◽

Neonatal Hypoxia ◽

Hypoxia Ischemia ◽

Activator Inhibitor

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