Apolipoprotein E affects the central nervous system response to injury and the development of cerebral edema

2002 ◽  
Vol 51 (1) ◽  
pp. 113-117 ◽  
Author(s):  
John R. Lynch ◽  
Jose A. Pineda ◽  
Duncan Morgan ◽  
Lin Zhang ◽  
David S. Warner ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Apolipoprotein E ◽  
Cerebral Edema ◽  
System Response ◽  
The Central Nervous System

scholarly journals Social Isolation: How Can the Effects on the Cholinergic System Be Isolated?

2021 ◽  
Vol 12 ◽  
Author(s):  
Jaromir Myslivecek
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Social Isolation ◽  
Cholinergic System ◽  
System Response ◽  
Receptor Subtype ◽  
Receptor Subtypes ◽  
Cholinergic Signaling ◽  
The Central Nervous System

Social species form organizations that support individuals because the consequent social behaviors help these organisms survive. The isolation of these individuals may be a stressor. We reviewed the potential mechanisms of the effects of social isolation on cholinergic signaling and vice versa how changes in cholinergic signaling affect changes due to social isolation.There are two important problems regarding this topic. First, isolation schemes differ in their duration (1–165 days) and initiation (immediately after birth to adulthood). Second, there is an important problem that is generally not considered when studying the role of the cholinergic system in neurobehavioral correlates: muscarinic and nicotinic receptor subtypes do not differ sufficiently in their affinity for orthosteric site agonists and antagonists. Some potential cholinesterase inhibitors also affect other targets, such as receptors or other neurotransmitter systems. Therefore, the role of the cholinergic system in social isolation should be carefully considered, and multiple receptor systems may be involved in the central nervous system response, although some subtypes are involved in specific functions. To determine the role of a specific receptor subtype, the presence of a specific subtype in the central nervous system should be determined using search in knockout studies with the careful application of specific agonists/antagonists.

scholarly journals Expression and regulation of apolipoprotein E receptors in the cells of the central nervous system in culture: A review

AGE ◽  
2001 ◽  
Vol 24 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Qi-Wen Fan ◽  
Ichiro Iosbe ◽  
Hiroaki Asou ◽  
Katsuhiko Yanagisawa ◽  
Makoto Michikawa
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Apolipoprotein E ◽  
The Central Nervous System

scholarly journals Cerebral Edema Associated with Ventricular Reservoirs in Two Patients: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-5
Author(s):  
Marshall C. Cress ◽  
Angela N. Spurgeon ◽  
Douglas C. Miller ◽  
N. Scott Litofsky
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Cerebral Edema ◽  
Ventricular Catheter ◽  
Cns Metastasis ◽  
The Central Nervous System

Placement of ventricular reservoirs is a common practice to treat various tumors of the central nervous system (CNS). Ventricular catheter-reservoir-associated edema has been noted in the literature, but a thorough review of this literature identified no articles that examine this particular complication in neurooncology patients, specifically. We report two cases of ventricular catheter-reservoir-associated edema in patients receiving treatment for CNS metastasis.

Progesterone and allopregnanolone in the central nervous system: Response to injury and implication for neuroprotection

2015 ◽  
Vol 146 ◽  
pp. 48-61 ◽  
Author(s):  
R. Guennoun ◽  
F. Labombarda ◽  
M.C. Gonzalez Deniselle ◽  
P. Liere ◽  
A.F. De Nicola ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
System Response ◽  
The Central Nervous System

Functional neuroimaging demonstrates that ghrelin inhibits the central nervous system response to ingested lipid

Gut ◽  
2012 ◽  
Vol 61 (11) ◽  
pp. 1543-1551 ◽  
Author(s):  
Richard B Jones ◽  
Shane McKie ◽  
Nerys Astbury ◽  
Tanya J Little ◽  
Stacey Tivey ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Functional Neuroimaging ◽  
System Response ◽  
The Central Nervous System
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