scholarly journals Long‐term community noise exposure in relation to dementia, cognition, and cognitive decline in older adults

2020 ◽  
Author(s):  
Jennifer Weuve ◽  
Jennifer D'Souza ◽  
Todd Beck ◽  
Denis A. Evans ◽  
Joel D. Kaufman ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Noise Exposure ◽  
Community Noise

scholarly journals PREDICTION OF LONG-TERM COGNITIVE DECLINE FOLLOWING DELIRIUM IN OLDER ADULTS

2017 ◽  
Vol 1 (suppl_1) ◽  
pp. 1326-1326
Author(s):  
E. Devore ◽  
T. Fong ◽  
E.R. Marcantonio ◽  
E.M. Schmitt ◽  
S. Arnold ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Decline

scholarly journals Prediction of Long-term Cognitive Decline Following Postoperative Delirium in Older Adults

2017 ◽  
Vol 72 (12) ◽  
pp. 1697-1702 ◽  
Author(s):  
Elizabeth E Devore ◽  
Tamara G Fong ◽  
Edward R Marcantonio ◽  
Eva M Schmitt ◽  
Thomas G Travison ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Postoperative Delirium

scholarly journals Association Between Urate-Lowering Therapies and Cognitive Decline in Community-Dwelling Older Adults: A Post-Hoc Analysis of the MAPT Study.

2021 ◽  
Author(s):  
Luc MOLET-BENHAMOU ◽  
Kelly VIRECOULON GIUDICI ◽  
Philipe BARRETO ◽  
Yves ROLLAND
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Controlled Trial ◽  
Community Dwelling ◽  
Composite Score ◽  
Cognitive Score ◽  
Using Data ◽  
Community Dwelling Older Adults

Abstract Introduction Long-term use of urate-lowering therapies (ULT) may reduce inflammaging and thus prevent cognitive decline during aging. This article examined the association between long-term use of ULT and cognitive decline among community-dwelling older adults with spontaneous memory complaints. Material and methods We performed a secondary observational analysis using data of 1,673 participants ≥ 70 years old from the Multidomain Alzheimer Preventive Trial (MAPT Study), a randomized controlled trial assessing the effect of a multidomain intervention, the administration of polyunsaturated fatty acids (PUFA), both, or placebo on cognitive decline. We compared cognitive decline during the 5-year follow-up between three groups according to ULT use: participants treated with ULT during at least 75% of the study period (PT ≥ 75; n = 51), less than 75% (PT < 75; n = 31), and non-treated participants (PNT; n = 1,591). Cognitive function (measured by a composite score) was assessed at baseline, 6 months and every year for 5 years. Linear mixed models were performed and adjusted for age, sex, body mass index (BMI), diagnosis of arterial hypertension or diabetes, baseline composite cognitive score, and MAPT intervention groups. Results After the 5-year follow-up, only non-treated participants presented a significant decline in the cognitive composite score (mean change − 0.173, 95%CI -0.212 to -0.135; p < 0.0001). However, there were no differences in change of the composite cognitive score between groups (adjusted between-group difference for PNT vs. PT < 75: 0.089, 95%CI -0.160 to 0.338, p = 0.484; PNT vs. PT ≥ 75: 0.174, 95%CI -0.042 to 0.391, p = 0.115). Conclusion Use of ULT was not associated with reduced cognitive decline over a 5-year follow-up among community-dwelling older adults at risk of dementia.

scholarly journals Associations of lower vitamin D concentrations with cognitive decline and long-term risk of dementia and Alzheimer's disease in older adults

2017 ◽  
Vol 13 (11) ◽  
pp. 1207-1216 ◽  
Author(s):  
Catherine Feart ◽  
Catherine Helmer ◽  
Bénédicte Merle ◽  
François R. Herrmann ◽  
Cédric Annweiler ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Vitamin D ◽  
Cognitive Decline ◽  
Lower Vitamin

Cognitive short- and long-term effects of coffee cherry extract in older adults with mild cognitive decline

2019 ◽  
Vol 27 (6) ◽  
pp. 918-934 ◽  
Author(s):  
Jennifer L. Robinson ◽  
John M. Hunter ◽  
Tania Reyes-Izquierdo ◽  
Ruby Argumedo ◽  
Jessica Brizuela-Bastien ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Long Term Effects ◽  
Short And Long Term

Chronic Noise and Psychological Stress

1995 ◽  
Vol 6 (6) ◽  
pp. 333-338 ◽  
Author(s):  
Gary W. Evans ◽  
Staffan Hygge ◽  
Monika Bullinger
Keyword(s):  
Noise Exposure ◽  
Calibration Procedure ◽  
Long Term Memory ◽  
Community Noise ◽  
Challenging Tasks ◽  
Standardized Reading Test ◽  
Standardized Index ◽  
First Time

This article illustrates the value of incorporating psychological principles into the environmental sciences Psychophysiological, cognitive, motivational, and affective indices of stress were monitored among elementary school children chronically exposed to aircraft noise We demonstrate for the first time that chronic noise exposure is associated with elevated neuroendocrine and cardiovascular measures, muted cardiovascular reactivity to a task presented under acute noise, deficits in a standardized reading test administered under quiet conditions, poorer long-term memory, and diminished quality of life on a standardized index Children in high-noise areas also showed evidence of poor persistence on challenging tasks and habituation to auditory distraction on a signal-to-noise task They reported considerable annoyance with community noise levels, as measured utilizing a calibration procedure that adjusts for individual differences in rating criteria for annoyance judgments

scholarly journals Long‐Term Blood Pressure Variability and Risk of Cognitive Decline and Dementia Among Older Adults

2021 ◽  
Author(s):  
Michael E. Ernst ◽  
Joanne Ryan ◽  
Enayet K. Chowdhury ◽  
Karen L. Margolis ◽  
Lawrence J. Beilin ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Older Adults ◽  
Cognitive Impairment ◽  
Cognitive Decline ◽  
Blood Pressure Variability ◽  
Link Type ◽  
Incident Dementia ◽  
Increased Risk ◽  
The Impact

Background Blood pressure variability (BPV) in midlife increases risk of late‐life dementia, but the impact of BPV on the cognition of adults who have already reached older ages free of major cognitive deficits is unknown. We examined the risk of incident dementia and cognitive decline associated with long‐term, visit‐to‐visit BPV in a post hoc analysis of the ASPREE (Aspirin in Reducing Events in the Elderly) trial. Methods and Results ASPREE participants (N=19 114) were free of dementia and significant cognitive impairment at enrollment. Measurement of BP and administration of a standardized cognitive battery evaluating global cognition, delayed episodic memory, verbal fluency, and processing speed and attention occurred at baseline and follow‐up visits. Time‐to‐event analysis using Cox proportional hazards regression models were used to calculate hazard ratios (HR) and corresponding 95% CI for incident dementia and cognitive decline, according to tertile of SD of systolic BPV. Individuals in the highest BPV tertile compared with the lowest had an increased risk of incident dementia and cognitive decline, independent of average BP and use of antihypertensive drugs. There was evidence that sex modified the association with incident dementia (interaction P =0.02), with increased risk in men (HR, 1.68; 95% CI, 1.19–2.39) but not women (HR, 1.01; 95% CI, 0.72–1.42). For cognitive decline, similar increased risks were observed for men and women (interaction P =0.15; men: HR, 1.36; 95% CI, 1.16–1.59; women: HR, 1.14; 95% CI, 0.98–1.32). Conclusions High BPV in older adults without major cognitive impairment, particularly men, is associated with increased risks of dementia and cognitive decline. Registration URL: https://www.clinicaltrials.gov ; Unique identifier: NCT01038583; isrctn.com . Identifier: ISRCTN83772183.

Does Antidepressant Pharmacotherapy Delay, Mitigate, or Prevent Long-Term Cognitive Decline In Older Adults With A History Of Major Depression?

2014 ◽  
Vol 22 (3) ◽  
pp. S79-S80
Author(s):  
Aaron M. Koenig ◽  
Meryl A. Butters ◽  
A.E. Begley ◽  
Joshua M. Thorpe ◽  
Stewart J. Anderson ◽  
...  
Keyword(s):  
Older Adults ◽  
Major Depression ◽  
Cognitive Decline ◽  
History Of ◽  
Antidepressant Pharmacotherapy

Associations of Long-Term Noise Exposure and Cognition in Older Adults

2018 ◽  
Vol 2017 (1) ◽  
pp. 1034
Author(s):  
Sara D. Adar ◽  
Jennifer D’Souza ◽  
Jennifer Weuve ◽  
Todd Beck ◽  
Denis A. Evans ◽  
...  
Keyword(s):  
Older Adults ◽  
Noise Exposure
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