scholarly journals COVID‐19 pandemic: Quantifying the effects of the first lockdown on behavioral and cognitive measures using TASIC

2021 ◽  
Vol 17 (S1) ◽  
Author(s):  
Jenna Stevenson ◽  
Firoza Z Lussier ◽  
Stijn Servaes ◽  
Mira Chamoun ◽  
Nesrine Rahmouni ◽  
...  
Keyword(s):  
Cognitive Measures

French Adaptation of the Childhood Executive Functioning Inventory (CHEXI)

2013 ◽  
Vol 29 (2) ◽  
pp. 149-155 ◽  
Author(s):  
Corinne Catale ◽  
Caroline Lejeune ◽  
Sarah Merbah ◽  
Thierry Meulemans
Keyword(s):  
Working Memory ◽  
Executive Functioning ◽  
Factor Analyses ◽  
Cognitive Measures ◽  
Factor Solution ◽  
Confirmatory Factor Analyses ◽  
Confirmatory Factor ◽  
Rating Instrument ◽  
Functioning Inventory ◽  
Test Retest Reliability

Thorell and Nyberg (2008 ) recently developed the Childhood Executive Functioning Inventory (CHEXI), a new rating instrument for executive functioning in day-to-day life which can be divided into four subscales: working memory, planning, inhibition, and regulation. Using an exploratory factor analysis on data from young Swedish children attending kindergarten, Thorell and Nyberg (2008 ) found a two-factor solution that taps working memory and inhibition. In the present study, we explored the psychometric characteristics of the French adaptation of the CHEXI. A group of 95 parents of 5- and 6-year-old children completed the CHEXI, 87 of whom were given clinical inhibition and working memory tasks. Confirmatory factor analyses confirmed the two-factor solution based on inhibition and working memory that was identified in the original study of Swedish children. Supplementary results indicated good internal and test-retest reliability for the entire scale, as well as for the two subscales identified. Correlation analyses showed no relationship between cognitive measures and the CHEXI subscales. Possible clinical applications for the CHEXI scales are discussed.

1561-P: Associations between ß-Cell Function and Cognitive Measures Differ in Youth vs. Adults with Impaired Glucose Tolerance (IGT) or Early Type 2 Diabetes (T2D)

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1561-P
Author(s):  
SUZANNE CRAFT ◽  
AMY CLAXTON ◽  
MARK TRIPPUTI ◽  
SHARON EDELSTEIN ◽  
SILVA A. ARSLANIAN ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Cell Function ◽  
Early Type ◽  
Cognitive Measures

scholarly journals Differential Cognitive Performance in Females and Males with Regular Cannabis Use

2021 ◽  
Vol 27 (6) ◽  
pp. 570-580
Author(s):  
Ashley M. Schnakenberg Martin ◽  
Deepak Cyril D’Souza ◽  
Sharlene D. Newman ◽  
William P. Hetrick ◽  
Brian F. O’Donnell
Keyword(s):  
Digit Span ◽  
Verbal Learning ◽  
Verbal Working Memory ◽  
Cannabis Use ◽  
Neurocognitive Deficits ◽  
Psychomotor Speed ◽  
High Concentration ◽  
Cognitive Measures ◽  
Biological Sex ◽  
Learning Test

AbstractObjectives:Preclinical and clinical studies suggest that males and females may be differentially affected by cannabis use. This study evaluated the interaction of cannabis use and biological sex on cognition, and the association between observed cognitive deficits and features of cannabis use.Methods:Cognitive measures were assessed in those with regular, ongoing, cannabis use (N = 40; 22 female) and non-using peers (N = 40; 23 female). Intelligence, psychomotor speed, and verbal working memory were measured with the Wechsler Abbreviated Scale of Intelligence, Digit Symbol Test, and Digit Span and Hopkins Verbal Learning Test, respectively. Associations between cognitive measures and cannabis use features (e.g., lifetime cannabis use, age of initiation, time since last use of cannabis, recent high-concentration tetrahydrocannabinoid exposure) were also evaluated.Results:No main effects of group were observed across measures. Significant interactions between group and biological sex were observed on measures of intelligence, psychomotor speed, and verbal learning, with greatest group differences observed between males with and without regular cannabis use. Psychomotor performance was negatively correlated with lifetime cannabis exposure. Female and male cannabis use groups did not differ in features of cannabis use.Conclusions:Findings suggest that biological sex influences the relationship between cannabis and cognition, with males potentially being more vulnerable to the neurocognitive deficits related to cannabis use.

Maternal serotonin transporter genotype and offsprings' clinical and cognitive measures of ADHD and ASD

2021 ◽  
pp. 110354
Author(s):  
Sabrina I. Hanswijk ◽  
Daan van Rooij ◽  
Jaap Oosterlaan ◽  
Marjolein Luman ◽  
Pieter J. Hoekstra ◽  
...  
Keyword(s):  
Serotonin Transporter ◽  
Cognitive Measures ◽  
Serotonin Transporter Genotype

scholarly journals Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Laura del Hoyo Soriano ◽  
Tracie C. Rosser ◽  
Debra R. Hamilton ◽  
Danielle J. Harvey ◽  
Leonard Abbeduto ◽  
...  
Keyword(s):  
Working Memory ◽  
Down Syndrome ◽  
Cognitive Functioning ◽  
Apgar Score ◽  
Visual Memory ◽  
Receptive Vocabulary ◽  
Cognitive Outcomes ◽  
Cognitive Testing ◽  
Cognitive Measures ◽  
Verbal Comprehension

AbstractThis study examined the contribution of the Apgar score at 1 and 5 min after birth to later cognitive functioning in 168 individuals with Down syndrome who were between 6 and 25 years of age at time of cognitive testing. Our results showed that a lower Apgar score at 1 min was related to a worse performance in later cognitive measures of receptive vocabulary, verbal comprehension and production, visual memory and working memory. Results also showed that a lower Apgar score at 5 min was only related to worse later outcomes of verbal comprehension and production and auditory working memory. Our findings suggest a need for future studies investigating how specific perinatal events reflected in the Apgar score are linked to later cognitive functioning in individuals with Down syndrome.

scholarly journals Fluid Cognitive Abilities Are Important for Learning and Retention of a New, Explicitly Learned Walking Pattern in Individuals After Stroke

2021 ◽  
pp. 154596832110010
Author(s):  
Margaret A. French ◽  
Matthew L. Cohen ◽  
Ryan T. Pohlig ◽  
Darcy S. Reisman
Keyword(s):  
Cognitive Abilities ◽  
Step Length ◽  
Cognitive Measures ◽  
Retention Models ◽  
Wechsler Memory Scale ◽  
Walking Pattern ◽  
Learning Principles ◽  
The Relationship ◽  
Sequential Regression ◽  
Neurologically Intact

Background There is significant variability in poststroke locomotor learning that is poorly understood and affects individual responses to rehabilitation interventions. Cognitive abilities relate to upper extremity motor learning in neurologically intact adults, but have not been studied in poststroke locomotor learning. Objective To understand the relationship between locomotor learning and retention and cognition after stroke. Methods Participants with chronic (>6 months) stroke participated in 3 testing sessions. During the first session, participants walked on a treadmill and learned a new walking pattern through visual feedback about their step length. During the second session, participants walked on a treadmill and 24-hour retention was assessed. Physical and cognitive tests, including the Fugl-Meyer-Lower Extremity (FM-LE), Fluid Cognition Composite Score (FCCS) from the NIH Toolbox -Cognition Battery, and Spatial Addition from the Wechsler Memory Scale-IV, were completed in the third session. Two sequential regression models were completed: one with learning and one with retention as the dependent variables. Age, physical impairment (ie, FM-LE), and cognitive measures (ie, FCCS and Spatial Addition) were the independent variables. Results Forty-nine and 34 participants were included in the learning and retention models, respectively. After accounting for age and FM-LE, cognitive measures explained a significant portion of variability in learning ( R2 = 0.17, P = .008; overall model R2 = 0.31, P = .002) and retention (Δ R2 = 0.17, P = .023; overall model R2 = 0.44, P = .002). Conclusions Cognitive abilities appear to be an important factor for understanding locomotor learning and retention after stroke. This has significant implications for incorporating locomotor learning principles into the development of personalized rehabilitation interventions after stroke.

scholarly journals Fear of Falling and Cognitive Decline in Healthy Aging Adults

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 265-265
Author(s):  
Rebecca Kraut ◽  
Roee Holtzer
Keyword(s):  
Older Adults ◽  
Executive Functions ◽  
Cognitive Decline ◽  
Healthy Aging ◽  
Fear Of Falling ◽  
Composite Score ◽  
Cognitive Measures ◽  
Delayed Recall ◽  
Memory And Attention ◽  
Aging Adults

Abstract Fear of Falling (FOF) is common and associated with poor mobility in aging but whether persistence of FOF endorsement influences cognitive decline has not been reported. Here we determined the effect of FOF, measured dichotomously and after accounting for persistence, on decline in global cognitive function (GCF), memory, and attention/executive functions. Older adults with persistent FOF (n=81; mean age=77.63±6.67 yrs; %female=74.1), transient FOF (n=60; mean age=76.93±6.01 yrs; %female=61.7), and no FOF (n=286; mean age=75.77±6.42 yrs; %female=49.3) were included. FOF was assessed through yes/no responses to “do you have a fear of falling?” at baseline. GCF was assessed using RBANS; memory was assessed using a composite score comprising the immediate and delayed recall index scores from RBANS; attention/executive functions were assessed via a composite score comprising TMT A & B, letter and category fluency tasks, and digit symbol modalities. Cognitive measures were administered annually for up to six years. Linear mixed effects models revealed that persistent FOF was associated with a worse decline in GCF compared to both transient FOF (estimate=0.78, p=.022) and no FOF (estimate=0.75, p=.004). Persistent FOF was also associated with a worse decline in memory compared to those with transient FOF (estimate=0.08, p=.004) and those with no FOF (estimate=0.06, p=.006). Associations between FOF status and decline in attention/executive functions were not significant. These findings demonstrate that persistent FOF is a risk factor for cognitive decline in community-residing older adults.

scholarly journals Assessing mood and cognitive functioning in acute stroke: clinical usability of a Visual Analogue Mood Scale (VAMS)

2021 ◽  
Author(s):  
Fabrizio Pasotti ◽  
Sabrina Serranò ◽  
Edoardo Nicolò Aiello ◽  
Chiara Gramegna ◽  
Matteo Querzola ◽  
...  
Keyword(s):  
Acute Stroke ◽  
Mood State ◽  
Psychometric Evaluation ◽  
Depressive Mood ◽  
Control Line ◽  
Emotional States ◽  
Cognitive Measures ◽  
Stroke Patients ◽  
Clock Drawing Test ◽  
Mood Scale

Abstract Background Patients suffering from stroke in the acute/post-acute phases often present with depressive mood — which negatively impacts on patients’ prognosis. However, psychometric evaluation of mood in acute stroke patients may be challenging due to cognitive deficits. Tools investigating emotional states via a vertical analogue line may overcome language/visuo-spatial disorders. This study thus aimed at (a) investigating the clinical usability of a Visual Analogue Mood Scale (VAMS) in acute stroke patients and (b) investigating the interplay between mood and cognition in this population. Methods Forty-one acute stroke patients were compared to 41 age-, education- and sex-matched healthy participants (HPs) on the VAMS and on cognitive measures (mental performance in acute stroke, MEPS). A control line bisection (LB) task was administered to control for potential visuo-spatial deficits in patients. Results Patients reported higher depression levels than HPs (lower VAMS scores); this between-group difference stayed significant when covarying for LB scores. MEPS scores discriminated patients from HPs; among cognitive measures, only the Clock drawing test (CDT) was positively associated with VAMS scores. Lesion side did not affect patients’ mood state; however, disease duration was inversely related to VAMS scores. Discussion The VAMS proved to be a suitable tool for assessing mood in acute stroke patients, as being independent from post-stroke cognitive sequelae. The CDT might represent an adequate measure of depression-induced, post-stroke cognitive efficiency decrease. Mood disorders might occur and thus should be adequately addressed also in post-acute phases — likely due to longer hospitalization times and regression of anosognosic features.

scholarly journals Neuro-Cognitive Profile of Morning and Evening Chronotypes at Different Times of Day

2021 ◽  
pp. 097275312199028
Author(s):  
Nanditha Venkat ◽  
Meenakshi Sinha ◽  
Ramanjan Sinha ◽  
Jayshri Ghate ◽  
Babita Pande
Keyword(s):  
Statistical Tests ◽  
Power Spectral Analysis ◽  
Significant Negative Correlation ◽  
Cognitive Status ◽  
Event Related Potential ◽  
Fast Fourier Transformation ◽  
P300 Latency ◽  
Cognitive Measures ◽  
Circadian Time ◽  
Beta Power

Background: Chronotype is the circadian time preference for sleep–wake timings. However, its impact on cognitive performance is least explored. Objective: The present study investigated the effect of chronotype (morning “M” vs. evening “E”) on cognitive measures as a function of time of the day. In addition, the correlation between electroencephalogram (EEG) waves and subjective/objective cognitive measures were investigated. Method: Cognitive status of 28 adult male subjects (15 “M” and 13 “E”) was assessed objectively through event-related potential (ERP) by administering visual odd ball paradigm test and subjectively through Montreal Cognitive Assessment questionnaire. In addition, 20 to 30 min of resting EEG was recorded. Recordings were done from 8 to 10 am and from 4 to 6 pm on a single day. Power spectral analysis of EEG for alpha and beta waves at PZ and FZ cortical sites was done after subjecting selected epochs to fast Fourier transformation. Also, latency and amplitude of P300 potential from event-related potential record were measured. Appropriate statistical tests were applied for analysis. Results: Higher alpha and beta power was observed in “E” at PZ in the evening. “M” showed increased P300 latency and amplitude during evening session for frequent and rare stimuli and vice versa in “E.”’ Significant negative correlation was seen between latency of rare stimuli and alpha and beta power at FZ site during evening in “E” chronotype only. Conclusion: Result indicates better attention and alertness during evening hours in evening chronotypes and vice versa in morning chronotypes. The findings could be implemented to schedule the mental performance/cognitive load according to individual chronotype.

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