scholarly journals Cognition may improve with medium‐chain triglyceride oil supplementation: A pilot study

2021 ◽  
Vol 17 (S6) ◽  
Author(s):  
Heidi L Hillebrandt ◽  
Cintia B Dias ◽  
Edward S Barin ◽  
Pratishtha Chatterjee ◽  
Tejal M Shah ◽  
...  
Keyword(s):  
Pilot Study ◽  
Medium Chain Triglyceride ◽  
Medium Chain

scholarly journals The effects of a unique medium chain triglyceride complex on migraine symptoms: A beta pilot study

2020 ◽  
Vol 8 (3) ◽  
pp. 175-183
Author(s):  
Neil Ernest Wolkodoff ◽  
Gerald Martin Haase ◽  
Robert Alexander Firger
Keyword(s):  
Pilot Study ◽  
Controlled Trial ◽  
Medium Chain Triglyceride ◽  
Electronic Record ◽  
Baseline Period ◽  
High Concentration ◽  
Open Label ◽  
Potential Relief ◽  
Record Keeping ◽  
Medium Chain

Purpose: Migraine headaches are among the most common worldwide medical issues, and various drug therapies only offer limited relief. Medium chain triglyceride (MCT) oil has demonstrated clinical benefits in multiple domains, from enhanced overall energy to increased brain function. This pilot study investigated the potential relief provided from a unique proprietary formulation, including a high concentration MCT-containing blend on migraine frequency, duration, and severity over 30 days. Methods: Fourteen (n=14) chronic migraine sufferers (migraineurs) were prospectively selected to participate in the open-label trial of this patented complex. Participants were instructed to maintain a consistent lifestyle, health factors, and medications while consuming the study compound. Because of the current Corona virus pandemic, the original paper version of the migraine survey was converted to an electronic response form to allow subjects increased safety in rating episodes and symptoms. Results: Overall, the subjects reduced the number of migraine episodes by 39% from the baseline period compared to after 30 days of using the supplement. The average episode duration decreased from 388 minutes to 152 minutes, a 61% reduction. Days/events missed due to migraine severity or complications were reduced from five per month to two per month, a decrease of 60%. A combined measure of specific symptoms also decreased according to subject rating, by an average of 32%. Conclusion: In this beta pilot study, consumption of a high concentration MCT complex produced significant improvements in migraine symptoms in the three significant episode realms of frequency, duration, and lost days due to dysfunction. In addition, migraine symptom surveys can be converted to electronic record keeping, a benefit for both the patient and the clinician. These outcomes have provided further impetus to pursue a rigorous study of specific MCT products to reduce migraine symptoms. A formal confirmatory placebo-controlled trial has been initiated.

scholarly journals Stabilisation of Lutein and Lutein Esters with Polyoxyethylene Sorbitan Monooleate, Medium-Chain Triglyceride Oil and Lecithin

Foods ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 500
Author(s):  
Zala Gombač ◽  
Ilja Gasan Osojnik Črnivec ◽  
Mihaela Skrt ◽  
Katja Istenič ◽  
Andreja Knez Knafelj ◽  
...  
Keyword(s):  
Aqueous Solutions ◽  
Medium Chain Triglyceride ◽  
Storage Conditions ◽  
Sorbitan Monooleate ◽  
Medium Chain ◽  
Poorly Soluble

Lutein is a challenging compound to incorporate into food, as it is poorly soluble and unstable in aqueous solutions. In this study, the aim was to prepare stable encapsulates of lutein and lutein esters using feasible and straightforward techniques. Fine suspensions based on polyoxyethylene sorbitan monooleate and medium-chain triglyceride oil micelle-like units with 3.45% lutein esters or 1.9% lutein equivalents provided high encapsulation efficiencies of 79% and 83%, respectively. Lutein encapsulated in fine suspensions showed superior stability, as 86% was retained within the formulation over 250 days at 25 °C in the dark. Under the same storage conditions, only 38% of lutein remained in corresponding formulations. Higher encapsulation efficiencies were achieved with lecithin emulsions, at up to 99.3% for formulations with lutein, and up to 91.4% with lutein esters. In lecithin emulsions that were stored for 250 days, 17% and 80% of lutein and lutein esters, respectively, were retained within the formulations.

Rickets and a medium chain triglyceride diet

1973 ◽  
Vol 8 (3) ◽  
pp. 439-440 ◽  
Author(s):  
James P. Keating ◽  
Donald B. Strominger ◽  
John Poulos
Keyword(s):  
Medium Chain Triglyceride ◽  
Medium Chain ◽  
Medium Chain Triglyceride Diet

scholarly journals CORRECTION OF THE “PHYSIOLOGIC” MALABSORPTION OF THE PREMATURE BY A MEDIUM CHAIN TRIGLYCERIDE(MCT) FORMULA

1974 ◽  
Vol 8 (4) ◽  
pp. 385-385 ◽  
Author(s):  
C C Roy ◽  
M Ste-Marie ◽  
A Weber ◽  
H Bard ◽  
B Doray
Keyword(s):  
Medium Chain Triglyceride ◽  
Medium Chain

Medium-chain triglyceride loading test in carnitine-acylcarnitine translocase deficiency: Insights on treatment

1999 ◽  
Vol 22 (6) ◽  
pp. 733-739 ◽  
Author(s):  
R. Parini ◽  
F. Invernizzi ◽  
F. Menni ◽  
B. Garavaglia ◽  
D. Melotti ◽  
...  
Keyword(s):  
Medium Chain Triglyceride ◽  
Loading Test ◽  
Medium Chain ◽  
Acylcarnitine Translocase

Gastric Lipolysis and Fat Absorption in Preterm Infants: Effect of Medium-Chain Triglyceride or Long-Chain Triglyceride-Containing Formulas

PEDIATRICS ◽  
1989 ◽  
Vol 83 (1) ◽  
pp. 86-92 ◽  
Author(s):  
Margit Hamosh ◽  
Joel Bitman ◽  
Teresa H. Liao ◽  
N. R. Mehta ◽  
R. J. Buczek ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Weight Gain ◽  
Preterm Infants ◽  
Lipase Activity ◽  
Medium Chain Triglyceride ◽  
Fat Absorption ◽  
Medium Chain ◽  
Long Chain ◽  
Long Chain Triglyceride

The extent of gastric lipolysis, fat absorption, and infant weight gain was studied in 12 preterm infants (gestational age 28.75 ± 0.50 weeks, postnatal age 6.08 ± 0.81 weeks) fed medium-chain triglyceride or long-chain triglyceride formula for 1 week in a crossover design. The former formula contained 42% of 8:0 and 10:0 and 19% of 12:0, 14:0, and 16:0; the latter formula contained only 7% of 8:0 and 10:0 and 46% of 12:0, 14:0, and 16:0. Gastric aspirates were obtained on the second and third day of formula feeding for quantitation of lipase activity and of the extent of gastric lipolysis. Fat balance studies were conducted during the last three days of each feeding regimen. The study showed that (1) there was marked hydrolysis of formula fat in the stomach during feeding of either medium-chain triglyceride formula or long-chain triglyceride formula (20% and 16%, respectively); (2) lipase activity in the gastric aspirates was less during feeding of medium-chain triglyceride formula than before the meal, which suggested stimulation of lipase secretion by long-chain fatty acid released from long-chain triglyceride formula fat or more rapid binding of lipase to ingested lipid in the medium-chain triglyceride formula; (3) fatty acid distribution in glycerides and free fatty acids showed preferential release of medium-chain (8:0, 10:0) and long-chain unsaturated (18:1, 18:2) fatty acids in the stomach. The low content of 8:0 and 10:0 in gastric triglyceride and free fatty acids suggested that medium-chain fatty acids were absorbed directly in the stomach. (4) fat balance studies showed almost identical absorption rates (84.6% ± 3.1% and 82.8% ± 4.0%) and weight gain (23.0 ± 1.5 g/d and 20.8 ± 1.8 g/d) during feeding of either medium-chain triglyceride or long-chain triglyceride formula. In this study, in which each infant was fed either formula alternately, it was shown that although the extent of fat digestion varied among infants, medium-chain and long-chain triglyceride were absorbed to the same extent by most infants.

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