INVOKE‐2: A phase 2 randomized, double‐blind, placebo‐controlled study to evaluate the efficacy and safety of AL002 in participants with early Alzheimer’s disease

Robert Paul; Sam Jackson; Michael Ward; Aashka Joshi; Abraham Castro; Felix L Yeh; Yijie Liao; Glenn Morrison

doi:10.1002/alz.054615

INVOKE‐2: A phase 2 randomized, double‐blind, placebo‐controlled study to evaluate the efficacy and safety of AL002 in participants with early Alzheimer’s disease

Alzheimer s & Dementia ◽

10.1002/alz.054615 ◽

2021 ◽

Vol 17 (S9) ◽

Author(s):

Robert Paul ◽

Sam Jackson ◽

Michael Ward ◽

Aashka Joshi ◽

Abraham Castro ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Controlled Study ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Early Alzheimer’S Disease

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P3-033: RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO ASSESS TREATMENT OF BIIB092 IN SUBJECTS WITH EARLY ALZHEIMER'S DISEASE: TANGO PHASE 2 STUDY DESIGN

Alzheimer s & Dementia ◽

10.1016/j.jalz.2018.06.1388 ◽

2006 ◽

Vol 14 (7S_Part_20) ◽

pp. P1077-P1077 ◽

Cited By ~ 1

Author(s):

Elena Ratti ◽

Bjoern Sperling ◽

Tina Olsson ◽

Li Zhang ◽

Kumar Kandadi Muralidharan ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Study Design ◽

Controlled Study ◽

Phase 2 ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Study ◽

Early Alzheimer’S Disease

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A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Donepezil in Patients with Alzheimer's Disease in the Nursing Home Setting

Journal of the American Geriatrics Society ◽

10.1111/j.1532-5415.2001.49266.x ◽

2001 ◽

Vol 49 (12) ◽

pp. 1590-1599 ◽

Cited By ~ 204

Author(s):

Pierre N. Tariot ◽

Jeffrey L. Cummings ◽

Ira R. Katz ◽

Jacobo Mintzer ◽

Carlos A. Perdomo ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Nursing Home ◽

Controlled Study ◽

Efficacy And Safety ◽

Double Blind ◽

Home Setting ◽

Double Blind Placebo ◽

Nursing Home Setting

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Effect of hydroxychloroquine on progression of dementia in early Alzheimer's disease: an 18-month randomised, double-blind, placebo-controlled study

The Lancet ◽

10.1016/s0140-6736(01)05623-9 ◽

2001 ◽

Vol 358 (9280) ◽

pp. 455-460 ◽

Cited By ~ 130

Author(s):

Willem A Van Gool ◽

Henry C Weinstein ◽

Philip K Scheltens ◽

Gerard JM Walstra

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Controlled Study ◽

Double Blind ◽

Double Blind Placebo ◽

Early Alzheimer’S Disease

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Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer’s disease: randomized, double-blind, placebo-controlled study

Alzheimer s Research & Therapy ◽

10.1186/s13195-018-0415-6 ◽

2018 ◽

Vol 10 (1) ◽

Cited By ~ 24

Author(s):

Maarten Timmers ◽

Johannes Rolf Streffer ◽

Alberto Russu ◽

Yushin Tominaga ◽

Hiroko Shimizu ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Controlled Study ◽

Double Blind ◽

Double Blind Placebo ◽

Bace1 Inhibitor ◽

Early Alzheimer’S Disease

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Faculty Opinions recommendation of Efficacy and Safety of ABT-126 in Subjects with Mild-to-Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors: A Randomized, Double-Blind, Placebo-Controlled Study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726214328.793523096 ◽

2016 ◽

Author(s):

Guy Griebel

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholinesterase Inhibitors ◽

Controlled Study ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo

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Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer’s disease spectrum patients: a randomized, double-blind, placebo-controlled study and a two-period extension study

Alzheimer s Research & Therapy ◽

10.1186/s13195-020-00614-5 ◽

2020 ◽

Vol 12 (1) ◽

Cited By ~ 3

Author(s):

Gerald Novak ◽

Johannes Rolf Streffer ◽

Maarten Timmers ◽

David Henley ◽

H. Robert Brashear ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Extension Study ◽

Controlled Study ◽

Double Blind ◽

Double Blind Placebo ◽

Bace1 Inhibitor ◽

Disease Spectrum ◽

Early Alzheimer’S Disease

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A 24‐week double‐blind placebo‐controlled study of the efficacy and safety of the AMPA modulator S47445 in patients with mild to moderate Alzheimer's disease and depressive symptoms

Alzheimer s & Dementia Translational Research & Clinical Interventions ◽

10.1016/j.trci.2019.04.002 ◽

2019 ◽

Vol 5 (1) ◽

pp. 231-240 ◽

Cited By ~ 3

Author(s):

Katy Bernard ◽

Sylvie Gouttefangeas ◽

Sylvie Bretin ◽

Stéphanie Galtier ◽

Philippe Robert ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Depressive Symptoms ◽

Controlled Study ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo

Download Full-text

O4-11-06: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 2 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF CRENEZUMAB IN PATIENTS WITH MILD TO MODERATE ALZHEIMER'S DISEASE

Alzheimer s & Dementia ◽

10.1016/j.jalz.2014.04.450 ◽

2014 ◽

Vol 10 ◽

pp. P275-P275 ◽

Cited By ~ 14

Author(s):

Jeffrey Cummings ◽

William Cho ◽

Michael Ward ◽

Michel Friesenhahn ◽

Flavia Brunstein ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Study

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Efficacy and Safety of ABT-126 in Subjects with Mild-to-Moderate Alzheimer’s Disease on Stable Doses of Acetylcholinesterase Inhibitors: A Randomized, Double-Blind, Placebo-Controlled Study

Journal of Alzheimer s Disease ◽

10.3233/jad-150978 ◽

2016 ◽

Vol 51 (4) ◽

pp. 1237-1247 ◽

Cited By ~ 15

Author(s):

Hana Florian ◽

Andreas Meier ◽

Serge Gauthier ◽

Stanley Lipschitz ◽

Yunzhi Lin ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholinesterase Inhibitors ◽

Controlled Study ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo

Download Full-text

Prevention of Early Alzheimer’s Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study

Frontiers in Aging Neuroscience ◽

10.3389/fnagi.2020.00155 ◽

2020 ◽

Vol 12 ◽

Author(s):

I-Chen Li ◽

Han-Hsin Chang ◽

Chuan-Han Lin ◽

Wan-Ping Chen ◽

Tsung-Han Lu ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Controlled Study ◽

Double Blind ◽

Double Blind Placebo ◽

Hericium Erinaceus ◽

Early Alzheimer’S Disease ◽

Erinacine A

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