scholarly journals Prospective and retrospective memory complaints in early and late stages of amnestic mild cognitive impairment

2021 ◽  
Vol 17 (S6) ◽  
Author(s):  
Seon Young Ryu ◽  
Sang Bong Lee ◽  
Taek Jun Lee ◽  
Yu Jin Jung
2009 ◽  
Vol 10 (1) ◽  
pp. 59-75 ◽  
Author(s):  
Anne Eschen ◽  
Mike Martin ◽  
Ursula Schreiter Gasser ◽  
Matthias Kliegel

AbstractCurrent management attempts for Alzheimer's disease (AD) focus on the identification of individuals in the preclinical stage. This has led to the development of the diagnostic concept of Mild Cognitive Impairment (MCI), which applies to individuals with declining cognitive abilities but largely preserved everyday functioning. Previous findings indicate that prospective memory deficits are a sensitive marker of preclinical AD and that awareness of prospective memory failures is particularly high, based on its dependence on executive functions. Thus, the goal of this study was to evaluate the usefulness of subjective prospective versus retrospective memory complaints for an initial screening for MCI and their respective associations with executive functions. 71 healthy older adults, 27 MCI patients, and 9 patients with mild AD completed the Prospective and Retrospective Memory Questionnaire (PRMQ) and three executive functions tests. The healthy and the MCI group could not be distinguished by their level of subjective prospective or retrospective memory complaints, but the mild AD patients differed from the other groups by complaining more about retrospective than prospective memory failures. For the healthy older adults, the prospective memory complaints were correlated to an inhibition test, whereas they did not correlate with any of the executive function tests in the MCI patients. In contrast, in both groups the retrospective memory complaints were related to a task switching test. The findings are discussed with respect to differences between the three groups in cognitive abilities, attention to failures of, use of mnemonic aids for, and everyday demands of prospective and retrospective memory.


2018 ◽  
Vol 33 (8) ◽  
pp. 1011-1018 ◽  
Author(s):  
Alexandre de Mendonça ◽  
Helena Felgueiras ◽  
Ana Verdelho ◽  
Sara Câmara ◽  
Cláudia Grilo ◽  
...  

2017 ◽  
Vol 13 (7S_Part_22) ◽  
pp. P1082-P1083
Author(s):  
Young Kyoung Jang ◽  
So-Hee Kim ◽  
Jae Seung Kim ◽  
Seung Jun Oh ◽  
Jee Hoon Roh ◽  
...  

2012 ◽  
Vol 13 (1) ◽  
pp. 83-89 ◽  
Author(s):  
Takehiko Doi ◽  
Hiroyuki Shimada ◽  
Hyuma Makizako ◽  
Daisuke Yoshida ◽  
Hiroshi Shimokata ◽  
...  

2015 ◽  
Vol 28 (3) ◽  
pp. 487-494 ◽  
Author(s):  
Seon Young Ryu ◽  
Sang Bong Lee ◽  
Tae Woo Kim ◽  
Taek Jun Lee

ABSTRACTBackground:The diagnostic relevance of subjective memory complaints (SMCs) in mild cognitive impairment (MCI) remains to be unresolved. The aim of this study is to determine clinical correlates of SMCs in MCI. Furthermore, we examined whether there are the differences due to different aspects of complaints (i.e. prospective memory (PM) versus retrospective memory (RM) complaints).Methods:We examined the cross-sectional associations between SMCs and depressive symptoms, instrumental activities of daily living (IADL), and cognitive measures in sixty-six individuals with MCI (mean age: 65.7 ± 8.01 years). The criteria for MCI included SMCs, objective cognitive impairment, normal general cognitive function, largely intact functional activities, and absence of dementia. SMCs were assessed using the Prospective and Retrospective Memory Questionnaire (PRMQ), which contains 16 items describing everyday memory failure of both PM and RM.Results:SMC severity (i.e. PRMQ total score) was associated with stronger depressive symptoms and worse IADL performance. SMCs were not related to cognitive measures. For PM and RM subscores, both depressive symptoms and IADL were related to the PRMQ-PM and -RM scores. The main contributors to these PM and RM scores were depressive symptoms and IADL impairment, respectively.Conclusions:This study suggests that SMCs are more associated with depressive symptoms and IADL problems than with cognitive performance in individuals with MCI. Furthermore, while PM and RM complaints are related to both depressive symptoms and IADL, the differences between these main contributors suggest that RM complaints based on IADL could be more associated with the organically driven pathological features of MCI.


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