scholarly journals Impact of vascular factors and tau deposition on functional brain network connectivity in participants of the Framingham Heart Study

2020 ◽  
Vol 16 (S5) ◽  
Author(s):  
Yashar Rahimpour ◽  
Jayandra J Himali ◽  
Alexa S Beiser ◽  
Mohamad Habes ◽  
Adrienne O’Donnell ◽  
...  
Keyword(s):  
Framingham Heart Study ◽  
Network Connectivity ◽  
Brain Network ◽  
Functional Brain ◽  
Heart Study ◽  
Functional Brain Network ◽  
Brain Network Connectivity

scholarly journals Variability in Infants' Functional Brain Network Connectivity Is Associated With Differences in Affect and Behavior

2021 ◽  
Vol 12 ◽  
Author(s):  
Caroline M. Kelsey ◽  
Katrina Farris ◽  
Tobias Grossmann
Keyword(s):  
Individual Differences ◽  
Long Range ◽  
Network Connectivity ◽  
Brain Network ◽  
Functional Brain ◽  
Default Mode ◽  
Behavioral Traits ◽  
Functional Brain Network ◽  
Brain Network Connectivity ◽  
And Behavior

Variability in functional brain network connectivity has been linked to individual differences in cognitive, affective, and behavioral traits in adults. However, little is known about the developmental origins of such brain-behavior correlations. The current study examined functional brain network connectivity and its link to behavioral temperament in typically developing newborn and 1-month-old infants (M [age] = 25 days; N = 75) using functional near-infrared spectroscopy (fNIRS). Specifically, we measured long-range connectivity between cortical regions approximating fronto-parietal, default mode, and homologous-interhemispheric networks. Our results show that connectivity in these functional brain networks varies across infants and maps onto individual differences in behavioral temperament. Specifically, connectivity in the fronto-parietal network was positively associated with regulation and orienting behaviors, whereas connectivity in the default mode network showed the opposite effect on these behaviors. Our analysis also revealed a significant positive association between the homologous-interhemispheric network and infants' negative affect. The current results suggest that variability in long-range intra-hemispheric and cross-hemispheric functional connectivity between frontal, parietal, and temporal cortex is associated with individual differences in affect and behavior. These findings shed new light on the brain origins of individual differences in early-emerging behavioral traits and thus represent a viable novel approach for investigating developmental trajectories in typical and atypical neurodevelopment.

scholarly journals F37. CACNA1C HYPOFUNCTION IN KETAMINE-ACTIVATED BRAIN NETWORKS IMPAIRS MEMORY CONSOLIDATION AND FUNCTIONAL BRAIN NETWORK CONNECTIVITY

2018 ◽  
Vol 44 (suppl_1) ◽  
pp. S233-S233
Author(s):  
Rebecca Hughes ◽  
Cosima Willi ◽  
Jayde Whittingham-Dowd ◽  
Susan Broughton ◽  
Greg Bristow ◽  
...  
Keyword(s):  
Memory Consolidation ◽  
Brain Networks ◽  
Network Connectivity ◽  
Brain Network ◽  
Functional Brain ◽  
Functional Brain Network ◽  
Brain Network Connectivity

scholarly journals Progressive tau aggregation does not alter functional brain network connectivity in seeded hTau.P301L mice

2020 ◽  
Vol 143 ◽  
pp. 105011
Author(s):  
Jan R. Detrez ◽  
Inès R.H. Ben-Nejma ◽  
Kristof Van Kolen ◽  
Debby Van Dam ◽  
Peter Paul De Deyn ◽  
...  
Keyword(s):  
Network Connectivity ◽  
Brain Network ◽  
Functional Brain ◽  
Functional Brain Network ◽  
Brain Network Connectivity ◽  
Tau Aggregation

Functional brain network connectivity in prenatal alcohol exposed neonates

2017 ◽  
Vol 27 ◽  
pp. S614
Author(s):  
A. Roos ◽  
J. Ipser ◽  
J. Fouche ◽  
H. Zar ◽  
R. Woods ◽  
...  
Keyword(s):  
Network Connectivity ◽  
Brain Network ◽  
Functional Brain ◽  
Functional Brain Network ◽  
Brain Network Connectivity ◽  
Prenatal Alcohol

Variability in functional brain network connectivity is associated with differences in newborn infants’ affect and behavior

2020 ◽  
Author(s):  
Caroline M. Kelsey ◽  
Katrina Farris ◽  
Tobias Grossmann
Keyword(s):  
Individual Differences ◽  
Long Range ◽  
Newborn Infants ◽  
Network Connectivity ◽  
Brain Network ◽  
Functional Brain ◽  
Default Mode ◽  
Functional Brain Network ◽  
Brain Network Connectivity ◽  
And Behavior

AbstractVariability in functional brain network connectivity has been linked to individual differences in cognitive, affective, and behavioral traits in adults. However, little is known about the developmental origins of such brain-behavior correlations. The current study examined functional brain network connectivity and its link to behavioral temperament in newborn infants (N = 75) using functional near-infrared spectroscopy (fNIRS). Specifically, we measured long-range connectivity between cortical regions approximating fronto-parietal, default mode, and homologous-interhemispheric networks. Our results show that connectivity in these functional brain networks varies across infants and maps onto individual differences in behavioral temperament. Specifically, connectivity in the fronto-parietal network was positively associated with regulation and orienting behaviors, whereas connectivity in the default mode network showed the opposite effect on these behaviors. Our analysis also revealed a significant positive association between the homologous-interhemispheric network and infants’ negative affect. The current results suggest that variability in long-range intra-hemispheric and cross-hemispheric functional connectivity between frontal, parietal and temporal cortex is associated with individual differences in affect and behavior. These findings shed new light on the brain origins of individual differences in early-emerging traits.

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