scholarly journals Trajectories of decline in cognitively complex everyday activities across the Alzheimer’s disease continuum

2020 ◽  
Vol 16 (S6) ◽  
Author(s):  
Mark A. Dubbelman ◽  
Roos J. Jutten ◽  
Sarah Tomaszewski Farias ◽  
Rebecca Amariglio ◽  
Rachel F. Buckley ◽  
...  
2020 ◽  
Vol 5 (3) ◽  
pp. 97-115
Author(s):  
Karolina Krajewska ◽  

Introduction. Alzheimer's disease (AD – Alzheimer Disease) is an incurable neurodegenerative disease. The main source of memory discomfort is destruc-tion. With age, irresistibly falling ill with it. Risk factors for the development of Alzheimer's disease are primarily: diabetes, female gender, hypertension and the lack of a control field. It is estimated that in Poland Alzheimer's disease affects about 200,000 people. According to statistics, 60% of all forms of de-mentia are AD. Aim of the study. The aim of the study is to present the activities that should be performed by a nurse caring for a patient with diagnosed Alzheimer's dis-ease. Case study. A 75-year-old patient admitted to the internal medicine ward, she has communication, content swallowing and spatial orientation disorders. It requires constant assistance in the performance of everyday activities. He complains of urinary and faecal incontinence. Conclusion. Thanks to the holistic approach to the patient, it is possible to ensure her correctness and the approach of the patient and her family.


Author(s):  
Antoni Martínez-Ballesté ◽  
Frederic Borràs Budesca ◽  
Agustí Solanas

The aim of this chapter is to describe a system for the private outdoor monitoring of patients with Mild Cognitive Impairments (MCI) and dementia. The system has been designed for patients suffering from early stages of Alzheimer's disease and people suffering from MCI and dementia. Virtually, the system may be applied to any person capable of living autonomously but might get lost whilst doing his/her everyday activities, due to a decrease in their cognitive function. The system uses off-the-shelf smartphones carried by patients to detect abnormal situations and to raise alarms accordingly. The authors describe the system, detail its features, and discuss its utility and relevance both technically and socially.


2017 ◽  
pp. 764-781
Author(s):  
Antoni Martínez-Ballesté ◽  
Frederic Borràs Budesca ◽  
Agustí Solanas

The aim of this chapter is to describe a system for the private outdoor monitoring of patients with Mild Cognitive Impairments (MCI) and dementia. The system has been designed for patients suffering from early stages of Alzheimer's disease and people suffering from MCI and dementia. Virtually, the system may be applied to any person capable of living autonomously but might get lost whilst doing his/her everyday activities, due to a decrease in their cognitive function. The system uses off-the-shelf smartphones carried by patients to detect abnormal situations and to raise alarms accordingly. The authors describe the system, detail its features, and discuss its utility and relevance both technically and socially.


2016 ◽  
Vol 15 (2) ◽  
pp. 50-53
Author(s):  
Dorota Kozak-Putowska ◽  
Joanna Iłżecka

Abstract Introduction. Alzheimer’s disease is characterized by progressive dementia process. There’s no medicine available to hinder that process. In case, the ill individual is unable to diagnose early symptoms of the disease, they call a doctor in the moment when a neurotic atrophy is irreversible. The patient is gradually losing self-reliance in everyday activities, the ability to take care of themselves, loses touch with the reality and surrounding world, begins to experience distressing symptoms and becomes isolated from the society. All these factors affect the life quality of an individual suffering from Alzheimer’s disease.Aim. The present article provides an analysis of literature on the quality of life in people suffering from Alzheimer’s disease.


2016 ◽  
pp. 693-708
Author(s):  
Antoni Martínez-Ballesté ◽  
Frederic Borràs Budesca ◽  
Agustí Solanas

The aim of this chapter is to describe a system for the private outdoor monitoring of patients with Mild Cognitive Impairments (MCI) and dementia. The system has been designed for patients suffering from early stages of Alzheimer's disease and people suffering from MCI and dementia. Virtually, the system may be applied to any person capable of living autonomously but might get lost whilst doing his/her everyday activities, due to a decrease in their cognitive function. The system uses off-the-shelf smartphones carried by patients to detect abnormal situations and to raise alarms accordingly. The authors describe the system, detail its features, and discuss its utility and relevance both technically and socially.


2019 ◽  
Vol 67 (1) ◽  
pp. 381-392 ◽  
Author(s):  
Carolina Delgado ◽  
Rodrigo C. Vergara ◽  
Melissa Martínez ◽  
Gada Musa ◽  
Fernando Henríquez ◽  
...  

2012 ◽  
Vol 21 (1) ◽  
pp. 43-57 ◽  
Author(s):  
Takehiko Yamaguchi ◽  
Déborah Alexandra Foloppe ◽  
Paul Richard ◽  
Emmanuelle Richard ◽  
Philippe Allain

Everyday action impairment is one of the diagnostic criteria of Alzheimer's disease and is associated with many serious consequences, including loss of functional autonomy and independence. It has been shown that the (re)learning of everyday activities is possible in Alzheimer's disease by using error reduction teaching approaches in naturalistic clinical settings. The purpose of this study is to develop a dual-modal virtual reality platform for training in everyday cooking activities in Alzheimer's disease and to establish its value as a training tool for everyday activities in these patients. Two everyday tasks and two error reduction learning methods were implemented within a virtual kitchen. Two patients with Alzheimer's disease and two healthy elderly controls were tested. All subjects were trained in two learning sessions on two comparable cooking tasks. Within each group (i.e., patients and controls), the order of the training methods was counterbalanced. Repeated measure analysis before and after learning was performed. A questionnaire of presence and a verbal interview were used to obtain information about the subjective responses of the participants to the VR experience. The results in terms of errors, omissions, and perseverations (i.e., repetitive behaviors) indicate that the patients performed worse than the controls before learning, but that they reached a level of performance similar to that of the controls after a short learning session, regardless of the learning method employed. This finding provides preliminary support for the value of the dual-modal virtual reality platform for training in everyday cooking activities in Alzheimer's disease. However, further work is needed before it is ready for clinical application.


2019 ◽  
Vol 42 ◽  
Author(s):  
Colleen M. Kelley ◽  
Larry L. Jacoby

Abstract Cognitive control constrains retrieval processing and so restricts what comes to mind as input to the attribution system. We review evidence that older adults, patients with Alzheimer's disease, and people with traumatic brain injury exert less cognitive control during retrieval, and so are susceptible to memory misattributions in the form of dramatic levels of false remembering.


Author(s):  
J. Metuzals ◽  
D. F. Clapin ◽  
V. Montpetit

Information on the conformation of paired helical filaments (PHF) and the neurofilamentous (NF) network is essential for an understanding of the mechanisms involved in the formation of the primary lesions of Alzheimer's disease (AD): tangles and plaques. The structural and chemical relationships between the NF and the PHF have to be clarified in order to discover the etiological factors of this disease. We are investigating by stereo electron microscopic and biochemical techniques frontal lobe biopsies from patients with AD and squid giant axon preparations. The helical nature of the lesion in AD is related to pathological alterations of basic properties of the nervous system due to the helical symmetry that exists at all hierarchic structural levels in the normal brain. Because of this helical symmetry of NF protein assemblies and PHF, the employment of structure reconstruction techniques to determine the conformation, particularly the handedness of these structures, is most promising. Figs. 1-3 are frontal lobe biopsies.


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