Giant cell lesions of the sinuses and skull base: A case series highlighting surgical management

Author(s):  
Samyuktha Melachuri ◽  
Manasa Melachuri ◽  
Raja R. Seethala ◽  
Katie Traylor ◽  
Paul A. Gardner ◽  
...  
2013 ◽  
Vol 19 (1) ◽  
pp. 12-21 ◽  
Author(s):  
Sampath Chandra Prasad ◽  
Enrico Piccirillo ◽  
Amjad Nuseir ◽  
Giuliano Sequino ◽  
Giuseppe De Donato ◽  
...  

2019 ◽  
Vol 30 (6) ◽  
pp. 1794-1797 ◽  
Author(s):  
Zhien Feng ◽  
Chong Wang ◽  
Bo Li ◽  
Aoming Cheng ◽  
Minghui Mao ◽  
...  

2020 ◽  
Vol 19 (4) ◽  
pp. 364-374
Author(s):  
Ahmed Habib ◽  
Matthew M Hanasono ◽  
Franco DeMonte ◽  
Ali Haider ◽  
Jonathan D Breshears ◽  
...  

Abstract BACKGROUND Skull base osteoradionecrosis (ORN) is a challenging treatment-related complication sometimes seen in patients with cancer. Although ORN management strategies for other anatomic sites have been reported, there is a paucity of data guiding the management of skull base ORN. OBJECTIVE To report a single-center tertiary care series of skull base ORN and to better understand the factors affecting ORN recurrence after surgical management. METHODS We conducted a retrospective cohort study of patients with skull base ORN treated at our center between 2003 and 2017. Univariate and multivariate binary logistic regressions were performed to identify predictors of recurrence. RESULTS A total of 31 patients were included in this study. The median age at ORN diagnosis was 61.1 yr (range, 32.8-84.9 yr). Of these 31 patients, 15 (48.4%) patients were initially treated medically. All 31 patients underwent surgery. Three (14.3%) of 21 patients treated with a free flap and 4 (50.0%) of 8 patients who underwent primary closure experienced recurrence. Cox regression analysis revealed that reconstruction with local tissue closure (P = .044) and ongoing treatment for active primary cancer (P = .022) were significant predictors of recurrence. The median overall survival from index surgery for ORN treatment was 83.9 mo. At 12-mo follow-up, 78.5% of patients were alive. CONCLUSION In this study, we assess the outcomes of our treatment approach, surgical debridement with vascularized reconstruction, on recurrence-free survival in patients with skull base ORN. Further studies with larger cohorts are needed to assess current treatment paradigms.


Neurosurgery ◽  
2021 ◽  
Vol 89 (Supplement_2) ◽  
pp. S149-S149
Author(s):  
Ahmed Habib ◽  
Matthew M Hanasono ◽  
Franco DeMonte ◽  
Ali Haider ◽  
Jonathan D Breshears ◽  
...  

2014 ◽  
Vol 75 (S 01) ◽  
Author(s):  
Iman Naseri ◽  
Melinda Davis-Malesevich ◽  
Michael Petr ◽  
Demetri Arnaoutakis ◽  
Daryoush Tavanaiepour

2014 ◽  
Vol 75 (S 02) ◽  
Author(s):  
Miguel Lopez-Gonzalez ◽  
Z. Bland ◽  
K. Zimmer

2016 ◽  
Vol 77 (S 02) ◽  
Author(s):  
Hannah North ◽  
Simon Freeman ◽  
Scott Rutherford ◽  
Andrew King ◽  
Chorlatte Hammerbeck-Ward ◽  
...  

2019 ◽  
Author(s):  
Gustavo Rangel ◽  
Mostafa Shahein ◽  
Thiago Felicio ◽  
Guilhermo Malave ◽  
Nyall London ◽  
...  

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