Transorbital‐transsinus resection of sinonasal malignancy with extraconal orbital extension

2021 ◽  
Author(s):  
Jeffrey Paul Radabaugh ◽  
Karina Richani‐Riverol ◽  
Amber U. Luong ◽  
William C. Yao ◽  
Tang Ho ◽  
...  
Keyword(s):  
Sinonasal Malignancy

scholarly journals Surgical Management Patterns of Sinonasal Malignancy: A Population-Based Study

2018 ◽  
Vol 80 (04) ◽  
pp. 371-379 ◽  
Author(s):  
Qasim Husain ◽  
Rohan R. Joshi ◽  
Jennifer R. Cracchiolo ◽  
Benjamin R. Roman ◽  
Ian Ganly ◽  
...  
Keyword(s):  
Surgical Management ◽  
Survival Rates ◽  
Tumor Resection ◽  
Population Based ◽  
Oncologic Outcomes ◽  
Surgical Approaches ◽  
Open Approach ◽  
National Cancer Database ◽  
Sinonasal Malignancy ◽  
Sinonasal Malignancies

Objectives Determining surgical trends and outcomes for sinonasal tumors is challenging given their low incidence and heterogeneous pathology. This study utilized the National Cancer Database (NCDB) to identify trends and outcomes associated with surgical management of sinonasal tumors. Design Retrospective database analysis. Setting National Cancer Database. Participants Patients with sinonasal malignancies identified from the NCDB between 2010 and 2015. Main Outcome Measures The primary outcome was the choice of surgical therapy used for sinonasal tumor resection: endoscopic versus open approach. Each was cohort analyzed with respect to various demographic and clinicopathologic factors. A treatment effect model was used to identify potential differences between surgical approaches. Survival was evaluated using Kaplan–Meier analysis. Results A total of 10,193 patients with sinonasal malignancies were identified in the NCDB database; of these, 2,292 had a documented subsite, histology, and definitive surgical treatment with documented surgical approach and were included in the analysis. About 71.9% of patients had an open approach and 28.1% a purely endoscopic procedures. Tumor histology, treatment facility type, margin status, and length of stay were all variables that were associated with significant differences between the open and endoscopic cohort. Five-year survival rates for the open and endoscopic cohorts were not significantly different (59.6 and 60.8%, respectively). Conclusions Assessment of the NCDB revealed that 28% patients with sinonasal malignancy were selected for endoscopic surgery. These patients had comparable oncologic outcomes to open resection.

Extended orbital exenteration for sinonasal malignancy with orbital apex extension: surgical technique and clinical analysis

2015 ◽  
Vol 123 (1) ◽  
pp. 52-58 ◽  
Author(s):  
Takashi Sugawara ◽  
Masaru Aoyagi ◽  
Takahiro Ogishima ◽  
Yoshihisa Kawano ◽  
Masashi Tamaki ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Skull Base ◽  
Perioperative Complications ◽  
Tumor Resection ◽  
Neurological Deficits ◽  
Orbital Exenteration ◽  
Orbital Apex ◽  
Orbital Cavity ◽  
Sinonasal Malignancy ◽  
Sinonasal Malignancies

OBJECT The majority of sinonasal malignancies present with advanced disease, and cure rates are generally poor. Surgical extirpation remains the mainstay of treatment. In cases of sinonasal malignancy with orbital apex extension, gross-total tumor resection requires orbital exenteration and bony skull base resection around the orbital apex to provide sufficient margins. In this retrospective study, the authors describe their surgical strategy in and technique for orbital exenteration with orbital apex resection in patients at Tokyo Medical and Dental University who had sinonasal malignancy with orbital apex extension. They also analyzed the clinical features of and the results in these patients. METHODS Between February 2001 and August 2012 at the authors' institution, sinonasal malignancy with orbital apex extension was treated using craniofacial tumor resection with orbital exenteration including skull base bone around the orbital apex. The authors describe this technique and analyze the surgical indications, extent of resection, primary tumor location, outcome, pathological findings, and neoadjuvant and adjuvant therapies of the patients who underwent the technique. RESULTS The patients consisted of 12 men and 3 women with a mean age of 47.7 years (range 14–79 years). The longest postoperative follow-up was 9.5 years, and the shortest was 0.67 year (mean 3.0 years). Tumor originated at the ethmoid sinus in 6 patients (40%), maxillary sinus in 5 (33%), nasal cavity in 2 (13%), and orbital cavity and maxillary bone in 1 patient each (7%). Histological analysis of tumor specimens revealed squamous cell carcinoma in 9 patients (60%), rhabdomyosarcoma in 2 (13%), and small cell carcinoma, mucoepidermoid carcinoma, adenoid cystic carcinoma, and Ewing sarcoma in 1 patient each (7%). Two patients experienced recurrences at 1 and 5 months after treatment; these patients died at 5 and 10 months after surgery, respectively. Estimated 5-year recurrence-free survival (RFS) was 86.7%, and estimated 5-year overall survival (OS) was 86.2%; there was no perioperative mortality. None of the patients had new neurological deficits as a result of the surgery, but 5 patients suffered infectious complications from the graft transplanted into the cavity after resection. There were no other perioperative complications. CONCLUSIONS These authors are the first to describe a technique for extended orbital exenteration with orbital apex skull base resection. The technique provided sufficient margins for gross-total resection of the sinonasal malignancy with orbital apex extension. The estimated 5-year OS and RFS rates were high, and the perioperative complication rate was acceptably low, demonstrating the safety and efficacy of this technique.

scholarly journals Development of minimally invasive surgery for sinonasal malignancy

2016 ◽  
Vol 133 (6) ◽  
pp. 405-411 ◽  
Author(s):  
A. Moya-Plana ◽  
D. Bresson ◽  
S. Temam ◽  
F. Kolb ◽  
F. Janot ◽  
...  
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Sinonasal Malignancy

Endoscopic Management of Sinonasal Malignancy

2006 ◽  
Vol 39 (3) ◽  
pp. 619-637 ◽  
Author(s):  
Pete S. Batra ◽  
Martin J. Citardi
Keyword(s):  
Endoscopic Management ◽  
Sinonasal Malignancy

Is there a link between nasal polyposis and increased risk for sinonasal malignancy?

2018 ◽  
Vol 120 (4) ◽  
pp. 439-440 ◽  
Author(s):  
Deena Pourang ◽  
Michael Batech ◽  
Kian Karimi ◽  
Javed Sheikh ◽  
Shefali Samant
Keyword(s):  
Nasal Polyposis ◽  
Sinonasal Malignancy ◽  
Increased Risk

Sinonasal Malignancy

2015 ◽  
pp. 71-71
Author(s):  
Geetha Chary
Keyword(s):  
Sinonasal Malignancy

Management of the Neck in Sinonasal Malignancy

2012 ◽  
pp. 142-142
Author(s):  
Niels Kokot ◽  
Lindsay Reder
Keyword(s):  
Sinonasal Malignancy

Treatment Outcomes of Sinonasal Malignancies Involving the Orbit

2021 ◽  
Author(s):  
Chul Ho Shin ◽  
Ho Jun Lee ◽  
Yoo-Sam Chung ◽  
Ji Heui Kim
Keyword(s):  
Survival Rates ◽  
Progression Free Survival ◽  
Oncological Outcome ◽  
Concurrent Chemoradiation ◽  
Treatment Modalities ◽  
Charlson Comorbidity Index Score ◽  
Adjuvant Radiation ◽  
Sinonasal Malignancy ◽  
Sinonasal Malignancies ◽  
Orbital Invasion

Abstract Objective Orbital invasion is associated with a poor prognosis in cases of sinonasal malignancy. This study aimed to analyze the oncological outcomes of sinonasal malignancies involving the orbit. Patients and Methods We reviewed the medical records of 116 patients with a sinonasal malignancy who had orbital invasion at initial diagnosis and followed up at least 6 months between June 1991 and October 2017 at a single institute. The overall survival (OS), disease-specific survival (DSS), and progression-free survival (PFS) rates according to the clinicopathological factors, extent to orbit, and treatment modality were compared. Results Patients were mainly treated with surgery and postoperative radiation (n = 39, 33.6%) and concurrent chemoradiation (n = 72, 62.1%). Only five patients (5.1%) underwent orbital exenteration. The OS, DSS, and PFS rates significantly decreased in patients older than 60 years of age and in patients with a higher Charlson Comorbidity Index Score (each p < 0.001). The OS and DSS rates were higher in patients at clinical T3 and N0 stage than in patients at clinical T4 and N1–2 stage (each p < 0.05). There were no significant differences in survival and local control rates according to the extent of orbital invasion, treatment modalities, and orbital preservation. However, neoadjuvant chemotherapy and adjuvant radiation or concurrent chemoradiation increased survival rates in the patients treated with surgery. Conclusion Orbit preservation and relatively successful oncological outcome could be obtained with surgery and adjuvant radiation or concurrent chemoradiation.

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