Total serum immunoglobulin E as a marker for missed antigens on in vitro allergy screening

2013 ◽  
Vol 3 (10) ◽  
pp. 782-787 ◽  
Author(s):  
Jeanne L. Hatcher ◽  
Samuel D. Cohen ◽  
J. Whit Mims
Keyword(s):  
Immunoglobulin E ◽  
Serum Immunoglobulin ◽  
Total Serum

scholarly journals Epigenome-wide association study of total serum immunoglobulin E in children: a life course approach

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Cheng Peng ◽  
Andres Cardenas ◽  
Sheryl L. Rifas-Shiman ◽  
Marie-France Hivert ◽  
Diane R. Gold ◽  
...  
Keyword(s):  
Life Course ◽  
Association Study ◽  
Immunoglobulin E ◽  
Serum Immunoglobulin ◽  
Total Serum ◽  
Life Course Approach

Prevalence of Airway Symptoms and Total Serum Immunoglobulin E Among Hairdressers in Bergen:

2003 ◽  
Vol 45 (11) ◽  
pp. 1201-1206 ◽  
Author(s):  
Bjørg Eli Hollund ◽  
Bente Elisabeth Moen ◽  
Grace M. Egeland ◽  
Erik Florvaag
Keyword(s):  
Immunoglobulin E ◽  
Serum Immunoglobulin ◽  
Total Serum ◽  
Airway Symptoms

scholarly journals Immunoglobulin E-rheumatoid factor in juvenile rheumatoid arthritis

2002 ◽  
Vol 57 (5) ◽  
pp. 209-216 ◽  
Author(s):  
Rosa Aparecida Ferreira ◽  
Virgínia Paes Leme Ferriani ◽  
Mônica Camargo Sopelete ◽  
Deise Aparecida Oliveira Silva ◽  
José Roberto Mineo ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Juvenile Rheumatoid Arthritis ◽  
Sedimentation Rate ◽  
Antinuclear Antibody ◽  
Immunoglobulin E ◽  
Latex Agglutination ◽  
Serum Immunoglobulin ◽  
Total Serum ◽  
Erythrocyte Sedimentation

OBJECTIVES: To determine the presence of immunoglobulin E-rheumatoid factor in patients with juvenile rheumatoid arthritis and to correlate it with clinical and laboratory parameters. METHODS: A multicenter prospective study was carried out from January 1993 to January 1999 with the enrollment of 3 centers of pediatric rheumatology. Ninety-one children with juvenile rheumatoid arthritis diagnosed according to the American College of Rheumatology criteria were studied: 38 (42%) with systemic, 28 (31%) with pauciarticular, and 25 (27%) with polyarticular onset. Ages ranged from 2.1 years to 22.6 years (mean 10.5 ± 4.7), with 59 (65%) girls. The control group consisted of 45 healthy children. The detection of immunoglobulin E-rheumatoid factor was carried out utilizing an enzyme-linked immunosorbent assay. Associations of immunoglobulin E-rheumatoid factor with immunoglobulin M-rheumatoid factor (latex agglutination test), total serum immunoglobulin E, erythrocyte sedimentation rate, antinuclear antibody, and functional and radiological classes III or IV were analyzed. RESULTS: Positive immunoglobulin E-rheumatoid factor was found in 15 (16.5%) of the 91 children with juvenile rheumatoid arthritis: 7 (18.5%) with systemic, 5 (18%) with pauciarticular, and 3 (12%) with polyarticular onset. A significant correlation was observed between immunoglobulin E-rheumatoid factor and total serum immunoglobulin E in the juvenile rheumatoid arthritis patients. No correlation was found between immunoglobulin E-rheumatoid factor and positive latex agglutination slide test, erythrocyte sedimentation rate, antinuclear antibody, or the functional and radiological classes III or IV in any disease onset group. In 4 out of 45 control children (8.9%), immunoglobulin E-rheumatoid factor was positive but with no correlation with total serum immunoglobulin E levels. CONCLUSIONS: Immunoglobulin E-rheumatoid factor could be detected in 16.5% of juvenile rheumatoid arthritis patients, particularly in those with high levels of total serum immunoglobulin E, and immunoglobulin E-rheumatoid factor appears not to be associated with disease activity or severity.

scholarly journals Frequency of Raised Total Serum Ig E, Sputum Eosinophilia and Blood Eosinophil Count in Patients with Severe Persistent Asthma

2021 ◽  
Vol 35 (1) ◽  
Author(s):  
Shanawer Qaiser
Keyword(s):  
Eosinophil Count ◽  
Inflammatory Markers ◽  
Immunoglobulin E ◽  
Persistent Asthma ◽  
Serum Immunoglobulin ◽  
Total Serum ◽  
Blood Eosinophil ◽  
Blood Eosinophil Count ◽  
Sputum Eosinophilia ◽  
Severe Persistent Asthma

Introduction: Asthma is a chronic inflammatory airway disorder that has several inflammatory phenotypes. Serum immunoglobulin E (IgE) and eosinophils are airway inflammation markers in asthmatic patients. In this research, we assessed the asthma severity with various inflammatory markers. Aims & Objectives: To find the frequency of raised total serum immunoglobulin E, sputum eosinophilia, and absolute blood eosinophil count in patients with severe persistent asthma. Place and duration of study: This study was conducted in Department of Pulmonology, Shaikh Zayed FPGMI, Lahore from 1st October 2018 to 1st April 2019. Material & Methods: A Cross-sectional study in which total of 125 patients were enrolled after fulfilling the inclusion criteria. Blood samples were taken with aseptic measures for total serum immunoglobulin E and absolute blood eosinophils count. Sputum was collected in the sterile jar and dispensed properly to the histopathology lab. Results: Of 125 patients, 44.8% were males, and 55.2% were females. The mean patient's age was 49.37 years, and the mean duration of symptoms was 25.49 years. Raised serum immunoglobulin E levels were seen in 74.4% patients, sputum eosinophilia was seen in 25.6% patients, and increased peripheral eosinophil count was seen in 55.2%. Age was significantly associated with sputum eosinophilia; however, no such association was seen between the other effect modifiers and inflammatory markers. Conclusion: Inflammatory markers immunoglobulin E, sputum and blood eosinophil levels were significantly raised in asthma patients. These can be used in the detection of asthma as their detection is easy, simple, and non-invasive, and they are directly linked to the inflammation.

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