Desloratadine-montelukast combination improves quality of life and decreases nasal obstruction in patients with perennial allergic rhinitis

2013 ◽  
Vol 3 (10) ◽  
pp. 801-806 ◽  
Author(s):  
Cemal Cingi ◽  
Fatih Oghan ◽  
Gorkem Eskiizmir ◽  
Aytekin Yaz ◽  
Ahmet Ural ◽  
...  
2016 ◽  
Vol 13 (2) ◽  
pp. 36-43
Author(s):  
T G Fedoskova ◽  
V M Svistushkin ◽  
E A Shevchik

Rhinitis (allergic, vasomotor and others) is common inflammatory disease of the nasal cavity. Clinical manifestations of chronic rhinitis, such as nasal obstruction, discharge from the nasal cavity, significantly reduce the quality of life of the patients. Efficacy of modern antihistamine - azelastin in the treatment of seasonal and perennial allergic rhinitis is presented in the article.


2019 ◽  
Vol 160 (6) ◽  
pp. 1118-1123 ◽  
Author(s):  
Grant S. Gillman ◽  
Giuseppe V. Staltari ◽  
Yue-Fang Chang ◽  
Jose L. Mattos

Objective Examine outcomes of septoplasty with turbinate reductions in patients with allergic rhinitis as compared to patients without allergic rhinitis using validated outcome and quality-of-life (QOL) instruments. Study Design Prospective observational cohort study. Setting Single surgeon, university hospital. Subjects and Methods Consecutive study-eligible patients with a symptomatic nasal septal deviation, with (n = 30) or without (n = 30) documented allergic rhinitis, were enrolled from March 2014 to February 2017. All patients subsequently underwent nasal septoplasty and inferior turbinate reductions. Outcomes were studied using the Nasal Obstruction Symptom Evaluation (NOSE) scale, mini–Rhinoconjunctivitis Quality of Life Questionnaire (mini-RQLQ), and Ease-of-Breathing (EOB) Likert scores completed preoperatively and, together with a patient satisfaction Likert, at 3 and 6 months postoperatively. Results NOSE scores, EOB scores, and mini-RQLQ scores improved significantly in both groups at 3 and 6 months postoperatively. Results were sustained from 3 to 6 months. Although mini-RQLQ scores in allergic patients were higher at all intervals, the magnitude of change in scores in both groups was comparable. Conclusion Although patients with allergic rhinitis report greater allergy-related QOL impairment (mini-RQLQ) on a day-to-day basis than nonallergic patients, this does not appear to attenuate the benefit they might experience from septoplasty and turbinate reductions when indicated for nasal obstruction. Furthermore, the symptomatic relief of their structural nasal obstruction appears to significantly improve their overall allergy-related quality of life. If appropriate expectations are set pre-operatively, allergic rhinitis is neither a contraindication nor a deterrent to septoplasty and turbinate reductions and these patients can reasonably expect a high degree of satisfaction post-operatively.


2014 ◽  
Vol 35 (4) ◽  
pp. 338-345 ◽  
Author(s):  
David P. Skoner ◽  
Craig F. LaForce ◽  
Robert A. Nathan ◽  
Eduardo R. Urdaneta ◽  
Michael A. Zielinski ◽  
...  

2010 ◽  
Vol 2 ◽  
pp. CMT.S4120
Author(s):  
Harissios Vliagoftis

Allergic rhinitis affects more than 20% and is responsible for very high direct and indirect costs. Nasal corticosteroids are the principle pharmaceutical option for the treatment of allergic rhinitis. They are more effective than all other therapeutic options and in addition to improving symptoms of allergic rhinitis they also improve quality of life in patients suffering from allergic rhinitis. There are many intranasal corticosteroids approved for the treatment of allergic rhinitis in pediatric and adult populations. Ciclesonide has shown so far a very good safety and pharmacokinetic profile and is effective for treatment of symptoms in both seasonal and perennial allergic rhinitis. This review summarizes the studies describing these effects of intranasal ciclesonide.


2009 ◽  
Vol 123 (2) ◽  
pp. S135-S135 ◽  
Author(s):  
A. Carvalho ◽  
U. Brito ◽  
J. Cunha ◽  
S. Torres ◽  
P. Duarte ◽  
...  

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