Increased presence of dendritic cells and dendritic cell chemokines in the sinus mucosa of chronic rhinosinusitis with nasal polyps and allergic fungal rhinosinusitis

2011 ◽  
Vol 1 (4) ◽  
pp. 296-302 ◽  
Author(s):  
Chris M. Ayers ◽  
Rodney J. Schlosser ◽  
Brendan P. O'Connell ◽  
Carl Atkinson ◽  
Ryan M. Mulligan ◽  
...  
2012 ◽  
Vol 50 (1) ◽  
pp. 1-12
Author(s):  
W.J. Fokkens ◽  
V.J. Lund ◽  
J. Mullol ◽  
C. Bachert ◽  
I. Alobid ◽  
...  

The European Position Paper on Rhinosinusitis and Nasal Polyps 2012 is the update of similar evidence based position papers published in 2005 and 2007. The document contains chapters on definitions and classification, we now also proposed definitions for difficult to treat rhinosinusitis, control of disease and better definitions for rhinosinusitis in children. More emphasis is placed on the diagnosis and treatment of acute rhinosinusitis. Throughout the document the terms chronic rhinosinusitis without nasal polyps (CRSsNP) and chronic rhinosinusitis with nasal polyps (CRSwNP) are used to further point out differences in pathophysiology and treatment of these two entities. There are extensive chapters on epidemiology and predisposing factors, inflammatory mechanisms, (differential) diagnosis of facial pain, genetics, cystic fibrosis, aspirin exacerbated respiratory disease, immunodeficiencies, allergic fungal rhinosinusitis and the relationship between upper and lower airways. The chapters on paediatric acute and chronic rhinosinusitis are totally rewritten. Last but not least all available evidence for management of acute rhinosinusitis and chronic rhinosinusitis with or without nasal polyps in adults and children is analyzed and presented and management schemes based on the evidence are proposed. This executive summary for otorhinolaryngologists focuses on the most important changes and issues for otorhinolaryngologists. The full document can be downloaded for free on the website of this journal: http://www.rhinologyjournal.com.


2012 ◽  
Vol 147 (4) ◽  
pp. 773-781 ◽  
Author(s):  
Jennifer K. Mulligan ◽  
David R. White ◽  
Eric W. Wang ◽  
S. Ritter Sansoni ◽  
Helen Moses ◽  
...  

2019 ◽  
Vol 7 (2) ◽  
pp. 30 ◽  
Author(s):  
Sonya Marcus ◽  
John M. DelGaudio ◽  
Lauren T. Roland ◽  
Sarah K. Wise

A few chronic rhinosinusitis (CRS) variants have demonstrated a strong association with environmental allergy, including allergic fungal rhinosinusitis (AFRS) and central compartment atopic disease (CCAD). However, the overall relationship between CRS and allergy remains poorly defined. The goal of this review is to evaluate the relationship between CRS and allergy with a focus on specific CRS variants.


Immunobiology ◽  
2014 ◽  
Vol 219 (9) ◽  
pp. 729-736 ◽  
Author(s):  
Rogério Pezato ◽  
Claudina A. Pérez-Novo ◽  
Gabriele Holtappels ◽  
Natalie De Ruyck ◽  
Koen Van Crombruggen ◽  
...  

2011 ◽  
Vol 54 (2) ◽  
pp. 83-86 ◽  
Author(s):  
Aleksandar Perić ◽  
Danilo Vojvodić ◽  
Lidija Zolotarevski ◽  
Aneta Perić

We present a rare case of eosinophilic fungal rhinosinusitis with nasal polyps in a 32-year-old woman caused by basidiomycete fungusSchizophyllum commune. Diagnosis was done by the endoscopic nasal examination, computed tomography (CT) of the paranasal sinuses, the histopathological examination of polyps, the presence of eosinophils and fungal hyphae in nasal mucus and by the detection ofS. communeby culture. The patient was successfully treated by combination of oral itraconazole and topical corticosteroid therapy combined with surgery. The pathogenesis and diagnosis of allergic fungal rhinosinusitis are also discussed.


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