scholarly journals Fiber type composition of epaxial muscles is geared toward facilitating rapid spinal extension in the leaperGalago senegalensis

2018 ◽  
Vol 166 (1) ◽  
pp. 95-106 ◽  
Author(s):  
Emranul Huq ◽  
Andrea B. Taylor ◽  
Zuowei Su ◽  
Christine E. Wall
Keyword(s):  
Fiber Type ◽  
Fiber Type Composition ◽  
Type Composition ◽  
Epaxial Muscles

Fiber type composition of four hindlimb muscles of adult Fisher 344 rats

1999 ◽  
Vol 111 (2) ◽  
pp. 117-123 ◽  
Author(s):  
Robert S. Staron ◽  
William J. Kraemer ◽  
Robert S. Hikida ◽  
Andy C. Fry ◽  
Jerry D. Murray ◽  
...  
Keyword(s):  
Fiber Type ◽  
Fiber Type Composition ◽  
Hindlimb Muscles ◽  
Type Composition

Myostatin regulates fiber-type composition of skeletal muscle by regulating MEF2 and MyoD gene expression

2009 ◽  
Vol 296 (3) ◽  
pp. C525-C534 ◽  
Author(s):  
Alex Hennebry ◽  
Carole Berry ◽  
Victoria Siriett ◽  
Paul O'Callaghan ◽  
Linda Chau ◽  
...  
Keyword(s):  
Growth Factor ◽  
Target Genes ◽  
Fiber Type ◽  
Fiber Formation ◽  
Type I ◽  
Mobility Shift ◽  
Enhancer Activity ◽  
Fiber Type Composition ◽  
Nuclear Extracts ◽  
Type Composition

Myostatin (Mstn) is a secreted growth factor belonging to the tranforming growth factor (TGF)-β superfamily. Inactivation of murine Mstn by gene targeting, or natural mutation of bovine or human Mstn, induces the double muscling (DM) phenotype. In DM cattle, Mstn deficiency increases fast glycolytic (type IIB) fiber formation in the biceps femoris (BF) muscle. Using Mstn null (−/−) mice, we suggest a possible mechanism behind Mstn-mediated fiber-type diversity. Histological analysis revealed increased type IIB fibers with a concomitant decrease in type IIA and type I fibers in the Mstn−/−tibialis anterior and BF muscle. Functional electrical stimulation of Mstn−/−BF revealed increased fatigue susceptibility, supporting increased type IIB fiber content. Given the role of myocyte enhancer factor 2 (MEF2) in oxidative type I fiber formation, MEF2 levels in Mstn−/−tissue were quantified. Results revealed reduced MEF2C protein in Mstn−/−muscle and myoblast nuclear extracts. Reduced MEF2-DNA complex was also observed in electrophoretic mobility-shift assay using Mstn−/−nuclear extracts. Furthermore, reduced expression of MEF2 downstream target genes MLC1F and calcineurin were found in Mstn−/−muscle. Conversely, Mstn addition was sufficient to directly upregulate MLC promoter-enhancer activity in cultured myoblasts. Since high MyoD levels are seen in fast fibers, we analyzed MyoD levels in the muscle. In contrast to MEF2C, MyoD levels were increased in Mstn−/−muscle. Together, these results suggest that while Mstn positively regulates MEF2C levels, it negatively regulates MyoD expression in muscle. We propose that Mstn could regulate fiber-type composition by regulating the expression of MEF2C and MyoD during myogenesis.

Fast-to-slow shift of muscle fiber-type composition by dietary apple polyphenols in rats: Impact of the low-dose supplementation

2016 ◽  
Vol 88 (3) ◽  
pp. 489-499 ◽  
Author(s):  
Wataru Mizunoya ◽  
Shinpei Okamoto ◽  
Hideo Miyahara ◽  
Mariko Akahoshi ◽  
Takahiro Suzuki ◽  
...  
Keyword(s):  
Muscle Fiber ◽  
Low Dose ◽  
Fiber Type ◽  
Muscle Fiber Type ◽  
Fiber Type Composition ◽  
Type Composition ◽  
Muscle Fiber Type Composition

Relationship of Fiber Type Composition to Marbling and Tenderness of Bovine Muscle

1981 ◽  
Vol 46 (3) ◽  
pp. 708-710 ◽  
Author(s):  
C. R. CALKINS ◽  
T. R. DUTSON ◽  
G. C. SMITH ◽  
Z. L. CARPENTER ◽  
G. W. DAVIS
Keyword(s):  
Fiber Type ◽  
Bovine Muscle ◽  
Fiber Type Composition ◽  
Type Composition ◽  
Relationship Of

177 EFFECT OF SPRINT TRAINING FREQUENCY ON MUSCLE FIBER TYPE COMPOSITION

1993 ◽  
Vol 25 (Supplement) ◽  
pp. S33
Author(s):  
M. Esbj??rnsson ◽  
Y. H-Westing ◽  
P. Balsom ◽  
B. Sj??din ◽  
E. Jansson
Keyword(s):  
Muscle Fiber ◽  
Fiber Type ◽  
Muscle Fiber Type ◽  
Sprint Training ◽  
Fiber Type Composition ◽  
Type Composition ◽  
Training Frequency ◽  
Muscle Fiber Type Composition
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