Age estimation of immature human skeletal remains from the dimensions of the girdle bones in the postnatal period

2017 ◽  
Vol 163 (4) ◽  
pp. 772-783 ◽  
Author(s):  
Hugo F. V. Cardoso ◽  
Laure Spake ◽  
Louise T. Humphrey
Keyword(s):  
Age Estimation ◽  
Postnatal Period ◽  
Skeletal Remains ◽  
Human Skeletal Remains

Biological Age Estimation of Non-adult Human Skeletal Remains:

2017 ◽  
pp. 94-104
Author(s):  
Carla L. Burrell ◽  
Carole A. L. Davenport ◽  
Raymond J. Carpenter ◽  
James C. Ohman
Keyword(s):  
Age Estimation ◽  
Skeletal Remains ◽  
Biological Age ◽  
Human Skeletal Remains ◽  
Adult Human

Comparison of Two Methods for Isolating DNA from Human Skeletal Remains for STR Analysis

2011 ◽  
Vol 57 (3) ◽  
pp. 706-712 ◽  
Author(s):  
Cynthia Rucinski ◽  
Ayda L. Malaver ◽  
Emilio J. Yunis ◽  
Juan J. Yunis
Keyword(s):  
Skeletal Remains ◽  
Human Skeletal Remains ◽  
Str Analysis

scholarly journals The elusive parasite: comparing macroscopic, immunological, and genomic approaches to identifying malaria in human skeletal remains from Sayala, Egypt (third to sixth centuries AD)

2021 ◽  
Vol 13 (7) ◽  
Author(s):  
Alvie Loufouma Mbouaka ◽  
Michelle Gamble ◽  
Christina Wurst ◽  
Heidi Yoko Jäger ◽  
Frank Maixner ◽  
...  
Keyword(s):  
Diagnostic Tests ◽  
Sample Selection ◽  
Human Remains ◽  
Rapid Diagnostic Tests ◽  
Skeletal Remains ◽  
Pathological Changes ◽  
Human Skeletal Remains ◽  
The Past ◽  
A Site ◽  
Capture Sequencing

AbstractAlthough malaria is one of the oldest and most widely distributed diseases affecting humans, identifying and characterizing its presence in ancient human remains continue to challenge researchers. We attempted to establish a reliable approach to detecting malaria in human skeletons using multiple avenues of analysis: macroscopic observations, rapid diagnostic tests, and shotgun-capture sequencing techniques, to identify pathological changes, Plasmodium antigens, and Plasmodium DNA, respectively. Bone and tooth samples from ten individuals who displayed skeletal lesions associated with anaemia, from a site in southern Egypt (third to sixth centuries AD), were selected. Plasmodium antigens were detected in five of the ten bone samples, and traces of Plasmodium aDNA were detected in six of the twenty bone and tooth samples. There was relatively good synchronicity between the biomolecular findings, despite not being able to authenticate the results. This study highlights the complexity and limitations in the conclusive identification of the Plasmodium parasite in ancient human skeletons. Limitations regarding antigen and aDNA preservation and the importance of sample selection are at the forefront of the search for malaria in the past. We confirm that, currently, palaeopathological changes such as cribra orbitalia are not enough to be certain of the presence of malaria. While biomolecular methods are likely the best chance for conclusive identification, we were unable to obtain results which correspond to the current authentication criteria of biomolecules. This study represents an important contribution in the refinement of biomolecular techniques used; also, it raises new insight regarding the consistency of combining several approaches in the identification of malaria in past populations.

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