scholarly journals Long-term effects of tetanus toxoid inoculation on the demography and life expectancy of the Cayo Santiago rhesus macaques

2014 ◽  
Vol 77 (2) ◽  
pp. 211-221 ◽  
Author(s):  
Matthew J. Kessler ◽  
Raisa Hernández Pacheco ◽  
Richard G. Rawlins ◽  
Angelina Ruiz-Lambrides ◽  
Diana L. Delgado ◽  
...  
Keyword(s):  
Life Expectancy ◽  
Tetanus Toxoid ◽  
Rhesus Macaques ◽  
Long Term Effects ◽  
Cayo Santiago

scholarly journals Long-term effects of differential early rearing in rhesus macaques: Behavioral reactivity in adulthood

2011 ◽  
Vol 54 (5) ◽  
pp. 546-555 ◽  
Author(s):  
Christopher A. Corcoran ◽  
Peter J. Pierre ◽  
Tyler Haddad ◽  
Christina Bice ◽  
Stephen J. Suomi ◽  
...  
Keyword(s):  
Rhesus Macaques ◽  
Long Term Effects ◽  
Behavioral Reactivity ◽  
Early Rearing

scholarly journals A re-analysis of the long-term effects on life expectancy of the Great Finnish Famine of 1866–68

2013 ◽  
Vol 67 (3) ◽  
pp. 309-322 ◽  
Author(s):  
Gabriele Doblhammer ◽  
Gerard J. van den Berg ◽  
L. H. Lumey
Keyword(s):  
Life Expectancy ◽  
Long Term Effects

Long-term effects of infant rearing condition on the acquisition of dominance rank in juvenile and adult rhesus macaques (Macaca mulatta)

2002 ◽  
Vol 42 (1) ◽  
pp. 44-51 ◽  
Author(s):  
Meredith L. Bastian ◽  
Anne C. Sponberg ◽  
Anne C. Sponberg ◽  
Stephen J. Suomi ◽  
J. Dee Higley
Keyword(s):  
Macaca Mulatta ◽  
Rhesus Macaques ◽  
Dominance Rank ◽  
Long Term Effects ◽  
Rearing Condition

scholarly journals Long-Term Effects of Famine on Life Expectancy: A Re-Analysis of the Great Finnish Famine of 1866-1868

2011 ◽  
Author(s):  
Gabriele Doblhammer-Reiter ◽  
Gerard J. van den Berg ◽  
Lambert Lumey
Keyword(s):  
Life Expectancy ◽  
Long Term Effects

scholarly journals Mapping perspectives of inhabitants and professionals in deprived neighborhoods in the Netherlands

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
J A J Dierx
Keyword(s):  
Qualitative Research ◽  
Life Expectancy ◽  
The Netherlands ◽  
Physical Activities ◽  
Community Center ◽  
Long Term Effects ◽  
Self Reliance ◽  
Deprived Neighborhoods ◽  
Triple I Method

Abstract Background People living in deprived neighborhoods have been shown to have several social and health problems such as loneliness, feelings of unsafety, poor diet and overweight, resulting in more sick years (16 years) and shorter life expectancy (6 year; Buck & Maguire, 2015; Murtin et al., 2017). Interventions developed by professionals to reduce health inequalities, seem to have little long term effects possibly due to interventions not matching the perspectives of people in deprived neighborhoods. The present study is performed to map possible differences in perspectives between inhabitants and professionals in deprived neighborhoods using the Triple-I method. Methods The Triple-I method as qualitative research tool (Boonekamp, Dierx & Jansen, in publication) was used to gain insight in how inhabitants (N = 12) and health and social professionals (N = 18) percieve the deprived neighborhood. Inhabitants and professionals were in separate Triple-I sessions that all took place in a community center within the neighborhood. Results Results show that both inhabitants and professionals want to create more self-reliance of the inhabitants. However, professionals mention their skills in organizing and bringing logic in the actions of inhabitants whereas inhabitants mention their own ability to organize activities themselves. In addition where both mention ‘togetherness’ as topic, inhabitants refer to this as ‘meeting each other’, whereas professionals talk about ‘constructing powerful networks with inhabitants and other professionals’. According to professionals these networks can ‘create feelings of safety’, which inhabitants perceive as a result of ‘clean and green surrounding’. Conclusions This research corroborates the suggestion that professionals and inhabitants percieve their neighborhood differently. Interventions reducing health inequality might be more effective when approached from the perspective of and even developed and executed by the target group. Key messages Triple-I method is useable in asset mapping of inhabitants and professionals in deprived neighborhoods in the Netherlands. Triple-I mehtod is useable in stimulating physical activities and health in neighborhoods.

scholarly journals Long Term Effects of H. pylori and Carcinogen on TFF2 Expression in Gastric Mucosa of Rhesus Macaques

2011 ◽  
Vol 140 (5) ◽  
pp. S-316
Author(s):  
Matthew Goldman ◽  
Cristina Semino-Mora ◽  
Hui Liu ◽  
Wilfred P. dela Cruz ◽  
Carolyn A. Sullivan ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Rhesus Macaques ◽  
Long Term Effects ◽  
H Pylori

scholarly journals Long-term effects of wildfire smoke exposure during early life on the nasal epigenome in rhesus macaques

2022 ◽  
Vol 158 ◽  
pp. 106993
Author(s):  
Anthony P. Brown ◽  
Lucy Cai ◽  
Benjamin I. Laufer ◽  
Lisa A. Miller ◽  
Janine M. LaSalle ◽  
...  
Keyword(s):  
Early Life ◽  
Rhesus Macaques ◽  
Smoke Exposure ◽  
Long Term Effects ◽  
Wildfire Smoke

Ovarian Dysfunction in Fetally Irradiated Beagles

1977 ◽  
Vol 35 ◽  
pp. 658-659
Author(s):  
T. M. Seed ◽  
M. H. Sanderson ◽  
D. L. Gutzeit ◽  
T. E. Fritz ◽  
D. V. Tolle ◽  
...  
Keyword(s):  
Gamma Rays ◽  
Low Dose ◽  
Long Term Effects ◽  
Ovarian Dysfunction ◽  
Dose Rates ◽  
Highly Sensitive ◽  
Microscopic Evaluation ◽  
Ovarian Pathology ◽  
Normal Offspring

The developing mammalian fetus is thought to be highly sensitive to ionizing radiation. However, dose, dose-rate relationships are not well established, especially the long term effects of protracted, low-dose exposure. A previous report (1) has indicated that bred beagle bitches exposed to daily doses of 5 to 35 R 60Co gamma rays throughout gestation can produce viable, seemingly normal offspring. Puppies irradiated in utero are distinguishable from controls only by their smaller size, dental abnormalities, and, in adulthood, by their inability to bear young.We report here our preliminary microscopic evaluation of ovarian pathology in young pups continuously irradiated throughout gestation at daily (22 h/day) dose rates of either 0.4, 1.0, 2.5, or 5.0 R/day of gamma rays from an attenuated 60Co source. Pups from non-irradiated bitches served as controls. Experimental animals were evaluated clinically and hematologically (control + 5.0 R/day pups) at regular intervals.

Ultrastructural investigations of MDL 19,660-induced effects on the canine platelet and megakaryocyte

1990 ◽  
Vol 48 (3) ◽  
pp. 374-375
Author(s):  
D.E. Loudy ◽  
J. Sprinkle-Cavallo ◽  
J.T. Yarrington ◽  
F.Y. Thompson ◽  
J.P. Gibson
Keyword(s):  
Antidepressant Drug ◽  
Beagle Dogs ◽  
Long Term Effects ◽  
Short Term ◽  
Platelet Counts ◽  
Toxicological Studies ◽  
Induced Aggregation ◽  
Internal Architecture

Previous short term toxicological studies of one to two weeks duration have demonstrated that MDL 19,660 (5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3Hl, 2,4-triazole-3-thione), an antidepressant drug, causes a dose-related thrombocytopenia in dogs. Platelet counts started to decline after two days of dosing with 30 mg/kg/day and continued to decrease to their lowest levels by 5-7 days. The loss in platelets was primarily of the small discoid subpopulation. In vitro studies have also indicated that MDL 19,660: does not spontaneously aggregate canine platelets and has moderate antiaggregating properties by inhibiting ADP-induced aggregation. The objectives of the present investigation of MDL 19,660 were to evaluate ultrastructurally long term effects on platelet internal architecture and changes in subpopulations of platelets and megakaryocytes.Nine male and nine female beagle dogs were divided equally into three groups and were administered orally 0, 15, or 30 mg/kg/day of MDL 19,660 for three months. Compared to a control platelet range of 353,000- 452,000/μl, a doserelated thrombocytopenia reached a maximum severity of an average of 135,000/μl for the 15 mg/kg/day dogs after two weeks and 81,000/μl for the 30 mg/kg/day dogs after one week.

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