Growth and developmental outcomes of three high-risk infant rhesus macaques (Macaca mulatta)

2007 ◽  
Vol 69 (5) ◽  
pp. 503-518 ◽  
Author(s):  
Amanda M. Dettmer ◽  
Lisa A. Houser ◽  
Gerald C. Ruppenthal ◽  
Saverio Capuano ◽  
Laura Hewitson
Keyword(s):  
High Risk ◽  
Macaca Mulatta ◽  
Rhesus Macaques ◽  
Developmental Outcomes ◽  
High Risk Infant ◽  
Infant Rhesus

scholarly journals Serotonin pathway gene–gene and gene–environment interactions influence behavioral stress response in infant rhesus macaques

2010 ◽  
Vol 22 (1) ◽  
pp. 35-44 ◽  
Author(s):  
Erin L. Kinnally ◽  
Genesio M. Karere ◽  
Leslie A. Lyons ◽  
Sally P. Mendoza ◽  
William A. Mason ◽  
...  
Keyword(s):  
Stress Response ◽  
High Risk ◽  
Emotional Reactivity ◽  
Rhesus Macaques ◽  
Behavioral Activity ◽  
Risk Alleles ◽  
Behavioral Stress ◽  
Gene Environment ◽  
Social Separation ◽  
Infant Rhesus

AbstractA subset of serotonin (5-HT) pathway polymorphisms has been shown to confer risk for psychological dysfunction, particularly in individuals who experience early adversity. Understanding the developmental processes underlying these Gene × Environment interactions will strengthen the search for risk factors for behavioral dysfunction. We investigated the combined influence of two serotonin pathway polymorphisms and species-atypical, and possibly adverse, rearing (nursery rearing [NR]) on two dimensions of behavioral stress response in infant rhesus macaques. We hypothesized that the experience of NR and possession of both “high-risk” genotypes (genotypes that are thought to confer low 5-HT function) would predict the greatest behavioral stress response to maternal/social separation. Using a matched-pair design, the impact of early experience and the serotonin transporter (rh5-HTTLPR) and monoamine oxidase A (rhMAO-A-LPR) promoter polymorphisms on behavioral reactivity of 136 infant rhesus macaques (90–120 days of age) during a 25-hr social separation/relocation procedure was assessed. Each pair included one infant reared with mother in a large, outdoor field enclosure (field rearing) and one infant reared in a nursery (NR). Pairs were matched for putative gene activity of each polymorphism, sex, age, and weight at testing. Behavioral responses in a “human intruder” test were recorded, and activity and emotional reactivity composites were created to detect different aspects of psychological adaptation to stress. Our hypothesis that high-risk groups would be the most reactive to stress was not entirely borne out. Rh5-HTTLPR × rhMAOA-LPR interactions predicted emotional reactivity and tended to predict behavioral activity scores. Carriers of the two “low-risk” alleles exhibited the lowest behavioral activity, as might be predicted, but carriers of both “high-risk” alleles were two of four genotype groups exhibiting the highest observed Emotional Reactivity. Gene × Gene interactions were exacerbated by the experience of nursery rearing, as predicted, however. Finally, we suggest that genetic or environmental factors may mitigate the risk for behavioral dysregulation illustrated in the patterns of behavioral activity and emotional reactivity displayed by infants.

Affiliative vocalizations in infant rhesus macaques (Macaca mulatta).

1992 ◽  
Vol 106 (3) ◽  
pp. 254-261 ◽  
Author(s):  
Ned H. Kalin ◽  
Steven E. Shelton ◽  
Charles T. Snowdon
Keyword(s):  
Macaca Mulatta ◽  
Rhesus Macaques ◽  
Infant Rhesus

scholarly journals Standard growth and diarrhea-associated growth faltering in captive infant rhesus macaques (Macaca mulatta)

2018 ◽  
Vol 80 (9) ◽  
pp. e22923 ◽  
Author(s):  
Andrew J. Haertel ◽  
Kamm Prongay ◽  
Lina Gao ◽  
Daniel H. Gottlieb ◽  
Byung Park
Keyword(s):  
Macaca Mulatta ◽  
Rhesus Macaques ◽  
Growth Faltering ◽  
Infant Rhesus

scholarly journals Hair cortisol predicts object permanence performance in infant rhesus macaques (Macaca mulatta)

2009 ◽  
Vol 51 (8) ◽  
pp. 706-713 ◽  
Author(s):  
Amanda M. Dettmer ◽  
Matthew F.S.X. Novak ◽  
Melinda A. Novak ◽  
Jerrold S. Meyer ◽  
Stephen J. Suomi
Keyword(s):  
Macaca Mulatta ◽  
Rhesus Macaques ◽  
Object Permanence ◽  
Hair Cortisol ◽  
Infant Rhesus

Hand Preference in Infant Rhesus Macaques (Macaca mulatta )

1997 ◽  
Vol 68 (3) ◽  
pp. 387-393
Author(s):  
Gregory Charles Westergaard ◽  
Maribeth Champoux ◽  
Stephen J. Suomi
Keyword(s):  
Macaca Mulatta ◽  
Rhesus Macaques ◽  
Hand Preference ◽  
Infant Rhesus
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