scholarly journals Isothiourea‐Catalyzed Functionalization of Pyrrolyl‐ and Indolylacetic Acid: Enantioselective Synthesis of Dihydropyridinones and One‐pot Synthesis of Pyridinones

2020 ◽  
Vol 9 (10) ◽  
pp. 1562-1566
Author(s):  
Shuyue Zhang ◽  
Lucas Bacheley ◽  
Claire M. Young ◽  
Daniel G. Stark ◽  
Timothy O'Riordan ◽  
...  
2015 ◽  
Vol 2 (1) ◽  
Author(s):  
Shengwei Wei ◽  
Bernhard Schmid ◽  
Fliur Z. Macaev ◽  
Serghei N. Curlat ◽  
Andrei V. Malkov ◽  
...  

Abstract The application of a convenient one-pot synthetic strategy, utilizing an in situ formed organocatalyst, to the enantioselective synthesis of anti-leukaemia agent (R)-convolutamydine A has been demonstrated.


2009 ◽  
Vol 11 (3) ◽  
pp. 8-14 ◽  
Author(s):  
Ali Gharib ◽  
Mohsen Daneshtalab ◽  
J. Scheeren ◽  
Fatemeh Bamoharram ◽  
Mina Roshani ◽  
...  

One-pot synthesis of (S)-2-(6-methoxynaphtalen-2-yl)propanoic acid, (S)-Naproxen using Preyssler and Keggin-type heteropolyacids as green and reusable catalysts A simple, clean and environmentally benign route to the enantioselective synthesis of (S)-2-(6-methoxynaphtalen-2-yl)propanoic acid, (S)-Naproxen 3 is described by using Preyssler heteropolyacid, H14[NaP5W30O110], as a green and reusable catalyst in water and in the presence of 1-(6-methoxynaphthalen-2-yl)propan-1-one 1, D-mannitol 2. The products were obtained in very good yields.


2019 ◽  
Vol 21 (3) ◽  
pp. 634-639 ◽  
Author(s):  
Peng Cui ◽  
Qixing Liu ◽  
Juan Wang ◽  
Huan Liu ◽  
Haifeng Zhou

A highly enantioselective synthesis of β-hydroxysulfones from inexpensive and readily available alkynes via a consecutive one-pot reaction in MeOH/H2O under mild conditions is described.


2020 ◽  
Author(s):  
Lucien Caspers ◽  
Julian Spils ◽  
Mattis Damrath ◽  
Enno Lork ◽  
Boris Nachtsheim

In this article we describe an efficient approach for the synthesis of cyclic diaryliodonium salts. The method is based on benzyl alcohols as starting materials and consists of an Friedel-Crafts-arylation/oxidation sequence. Besides a deep optimization, particluar focusing on the choice and ratios of the utilized Bronsted-acids and oxidants, we explore the substrate scope of this transformation. We also discuss an interesting isomerism of cyclic iodonium salts substituted with aliphatic substituents at the bridge head carbon. <br>


2017 ◽  
Vol 7 (12) ◽  
pp. 1192-1195
Author(s):  
Y. I. Shaikh ◽  
G. M. Nazeruddin ◽  
Khursheed Ahmed

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