Transition‐Metal‐Free Approaches to Arylsulfones using Benzylic Ammonium Salts through C−N Bond Cleavage

2020 ◽  
Vol 9 (2) ◽  
pp. 247-250 ◽  
Author(s):  
Yishuai Liu ◽  
Haibo Zhu ◽  
Liu Yang ◽  
Zongbo Xie ◽  
Guofang Jiang ◽  
...  
Keyword(s):  
Transition Metal ◽  
Bond Cleavage ◽  
Ammonium Salts ◽  
Metal Free

Transition-metal-free and base promoted C–C bond formation via C–N bond cleavage of organoammonium salts

2021 ◽  
Author(s):  
Tao Zhang ◽  
Kunyu Wang ◽  
Yuting Ke ◽  
Yuanyuan Tang ◽  
Long Liu ◽  
...  
Keyword(s):  
Transition Metal ◽  
Bond Cleavage ◽  
Bond Formation ◽  
Ammonium Salts ◽  
Metal Free ◽  
Bond Forming ◽  
Benzyl Ammonium

A transition-metal-free and base promoted C–C bond forming reaction of benzyl C(sp3)-H bond with organoammonium salts via C–N bond cleavage has been reported. Benzyl ammonium salts as well as cinnamyl...

scholarly journals Selective C-N σ Bond Cleavage in Azetidinyl Amides under Transition Metal-Free Conditions

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 459 ◽  
Author(s):  
Hengzhao Li ◽  
Zemin Lai ◽  
Adila Adijiang ◽  
Hongye Zhao ◽  
Jie An
Keyword(s):  
Electron Transfer ◽  
Transition Metal ◽  
Transfer Reaction ◽  
Bond Cleavage ◽  
Electron Transfer Reaction ◽  
Amide Bond ◽  
Single Electron Transfer ◽  
Reaction Conditions ◽  
Metal Free ◽  
Single Electron Transfer Reaction

Functionalization of amide bond via the cleavage of a non-carbonyl, C-N σ bond remains under-investigated. In this work, a transition-metal-free single-electron transfer reaction has been developed for the C-N σ bond cleavage of N-acylazetidines using the electride derived from sodium dispersions and 15-crown-5. Of note, less strained cyclic amides and acyclic amides are stable under the reaction conditions, which features the excellent chemoselectivity of the reaction. This method is amenable to a range of unhindered and sterically encumbered azetidinyl amides.

scholarly journals Na2CO3-promoted thioesterification via N–C bond cleavage of amides to construct thioester derivatives

2019 ◽  
Vol 43 (11-12) ◽  
pp. 486-492
Author(s):  
Jiasi Tao ◽  
Weijie Yu ◽  
Jin Luo ◽  
Tao Wang ◽  
Wanling Ge ◽  
...  
Keyword(s):  
Transition Metal ◽  
Bond Cleavage ◽  
Metal Free

A mild, efficient, and transition-metal-free catalytic strategy is developed to construct thioesters via selective N–C bond cleavage of Boc2-activated primary amides. This strategy is successfully carried out with stoichiometric Na2CO3 as the base and provides the corresponding products in moderate to excellent yields.

Catalytic conversion of ketones to esters via C(O)–C bond cleavage under transition-metal free conditions

2020 ◽  
Vol 56 (58) ◽  
pp. 8143-8146
Author(s):  
Murugan Subaramanian ◽  
Palmurukan M. Ramar ◽  
Jagannath Rana ◽  
Virendra Kumar Gupta ◽  
Ekambaram Balaraman
Keyword(s):  
Transition Metal ◽  
Bond Cleavage ◽  
Catalytic Conversion ◽  
Metal Free

The catalytic conversion of ketones to esters via C(O)–C bond cleavage under transition-metal free conditions is reported.

First synthesis of chloroformylphosphane complexes

2012 ◽  
Vol 85 (4) ◽  
pp. 829-834 ◽  
Author(s):  
Vitaly Nesterov ◽  
Tobias Heurich ◽  
Rainer Streubel
Keyword(s):  
Transition Metal ◽  
Bond Cleavage ◽  
Metal Free ◽  
Organophosphorus Chemistry

An approach to novel P-functional chloroformylphosphane complexes is described using the synthetic potential of lithium/halogeno phosphinidenoid tungsten(0) complexes. Similarly to transition-metal-free chloroformylphosphanes, the obtained complexes tend to eliminate CO via P–C bond cleavage to give the corresponding P-chlorophosphane complex derivatives. Nevertheless, this method allowed the isolation of the first complex derivatives, which will open new synthetic perspectives in organophosphorus chemistry.

Transition-metal-free C–C bond cleavage and formation: efficient synthesis of 2,3-diarylimidazo[1,2-α]pyridines from 2-aminopyridines and alkynoates

RSC Advances ◽  
2016 ◽  
Vol 6 (89) ◽  
pp. 86464-86467 ◽  
Author(s):  
Zhengwang Chen ◽  
Yuelu Wen ◽  
Guotian Luo ◽  
Min Ye ◽  
Qinghao Wang
Keyword(s):  
Transition Metal ◽  
Bond Cleavage ◽  
Cyclization Reaction ◽  
Efficient Synthesis ◽  
Metal Free ◽  
Highly Efficient

A highly efficient transition-metal-free cyclization reaction for the synthesis of 2,3-diarylimidazo[1,2-α]pyridines is described.

Transition-metal-free multinitrogenation of amides by C–C bond cleavage: a new approach to tetrazoles

2018 ◽  
Vol 54 (79) ◽  
pp. 11148-11151 ◽  
Author(s):  
Lian-Hua Li ◽  
Zhi-Jie Niu ◽  
Ying-Xiu Li ◽  
Yong-Min Liang
Keyword(s):  
Transition Metal ◽  
Bond Cleavage ◽  
Regioselective Synthesis ◽  
One Pot ◽  
New Approach ◽  
Metal Free

A metal-free brand-new one-pot multinitrogenation of amides for the chemo-, regioselective synthesis of 1,5-disubstituted tetrazoles has been developed.

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