Lewis-Acid-Catalyzed Intramolecular Aza-Friedel-Crafts Reaction ofN-tert-Butanesulfinyl Imines: Efficient Synthesis of Optically Active 9-Aminofluorene Derivatives

2013 ◽  
Vol 2 (1) ◽  
pp. 50-53 ◽  
Author(s):  
Yi Li ◽  
Ming-Hua Xu
Keyword(s):  
Lewis Acid ◽  
Optically Active ◽  
Efficient Synthesis ◽  
Acid Catalyzed

Efficient Synthesis of Diarylmethylamines via Lewis Acid Catalyzed Friedel–Crafts Reactions of Donor–Acceptor Aziridines with N,N-Dialkylanilines

Synthesis ◽  
2019 ◽  
Vol 52 (02) ◽  
pp. 281-289
Author(s):  
Yerin Kim ◽  
Yong Il Kwon ◽  
Sung-Gon Kim
Keyword(s):  
Lewis Acid ◽  
Efficient Synthesis ◽  
Broad Scope ◽  
Donor Acceptor ◽  
Acid Catalyzed ◽  
High Yields

A method for efficient and mild synthesis of diarylmethylamine scaffold, via Lewis acid catalyzed Friedel–Crafts reaction of donor­–acceptor aziridines with N,N-dialkylanilines to afford a biologically important diarylmethylamine derivatives in high yields (up to 88%), is presented. This reaction is suitable for the synthesis of various diarylmethylamine derivatives and has a broad scope for electron-rich arenes, including dimethoxybenzene.

ChemInform Abstract: Efficient Synthesis of C10 Chiron by Lewis Acid Catalyzed Rearrangement of (+)-α-3,4-Epoxycarane.

ChemInform ◽  
2010 ◽  
Vol 26 (30) ◽  
pp. no-no
Author(s):  
H. SASAI ◽  
T. ARAI ◽  
E. EMORI ◽  
M. SHIBASAKI
Keyword(s):  
Lewis Acid ◽  
Efficient Synthesis ◽  
Acid Catalyzed

ChemInform Abstract: Highly Efficient Synthesis of Quaternary α-Hydroxy Phosphonates via Lewis Acid Catalyzed Hydrophosphonylation of Ketones.

ChemInform ◽  
2010 ◽  
Vol 41 (11) ◽  
pp. no-no
Author(s):  
Xin Zhou ◽  
Yanling Liu ◽  
Lu Chang ◽  
Jiannan Zhao ◽  
Deju Shang ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Efficient Synthesis ◽  
Highly Efficient ◽  
Hydroxy Phosphonates ◽  
Acid Catalyzed

scholarly journals Acid-catalyzed chirality-transferring intramolecular Friedel–Crafts cyclization of α-hydroxy-α-alkenylsilanes

2019 ◽  
Vol 55 (59) ◽  
pp. 8635-8638 ◽  
Author(s):  
Kazuhiko Sakaguchi ◽  
Shunnichi Kubota ◽  
Wataru Akagi ◽  
Naoko Ikeda ◽  
Masato Higashino ◽  
...  
Keyword(s):  
Benzene Ring ◽  
Lewis Acid ◽  
Optically Active ◽  
Acid Catalyzed

Acid-catalyzed intramolecular Friedel–Crafts cyclization of optically active α-hydroxy-α-alkenylsilanes possessing a benzene ring (>99% ee) with TMSOTf as a Lewis acid gave enantio-enriched tetrahydronaphthalenes (up to 98% ee).

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