The identification of microdeletion syndromes and other chromosome abnormalities: Cytogenetic methods of the past, new technologies for the future

2007 ◽  
Vol 145C (4) ◽  
pp. 335-345 ◽  
Author(s):  
Lisa G. Shaffer ◽  
Bassem A. Bejjani ◽  
Beth Torchia ◽  
Susan Kirkpatrick ◽  
Justine Coppinger ◽  
...  
Keyword(s):  
New Technologies ◽  
Chromosome Abnormalities ◽  
The Past ◽  
Microdeletion Syndromes ◽  
The Future ◽  
Cytogenetic Methods

scholarly journals ANALISIS PAKAR TERHADAP TINGKAT TURBULENSI LINGKUNGAN ORGANISASI BISNIS TELEKOMUNIKASI SELULAR DI INDONESIA

2017 ◽  
Vol 9 (2) ◽  
Author(s):  
Dwi Idawati ◽  
Arya Hadi Dharmawan ◽  
Sjafri Mangkuprawira
Keyword(s):  
New Technologies ◽  
Secondary Data ◽  
Business Environment ◽  
Telecommunication Industry ◽  
Success Factor ◽  
Mobile Telecommunication ◽  
Corporate Leadership ◽  
The Past ◽  
Turbulent Environments ◽  
The Future

The key challenge for the telecommunication business industry in the global world’s is “assuring competitiveness and profitability” for their companies in turbulent environments. Never in history has the pace of change in the business environment been as rapid as it is now. Recent developments such as the global marketplace, customers’ demands that are differentiated by different buying power and product preferences in this environment, technological leadership is one of the key success factor. New technologies and new industries develop rapidly and customers are prepared to pay for the most newest technology. The company’s strengths and successful strategies of the corporate leadership in the past are likely to remain relevant in the future. The research findings revealed that the turbulent environment level in the mobile telecommunication industry was in the discontinuous –strategic level, where the future is not extension of the past. This environment situation facing by Indonesia’s telecomunication industry need the corporate leadership to challenge the organisation survival. This research is based on the qualitative descriptive method by using data obtained from telecommunication industry experts and secondary data.

scholarly journals CASA: tracking the past and plotting the future

2018 ◽  
Vol 30 (6) ◽  
pp. 867 ◽  
Author(s):  
M. T. Gallagher ◽  
D. J. Smith ◽  
J. C. Kirkman-Brown
Keyword(s):  
Gold Standard ◽  
New Technologies ◽  
Semen Analysis ◽  
Computational Approach ◽  
Human Semen ◽  
Laboratory Staff ◽  
Sperm Analysis ◽  
The Past ◽  
Computer Aided ◽  
The Future

The human semen sample carries a wealth of information of varying degrees of accessibility ranging from the traditional visual measures of count and motility to those that need a more computational approach, such as tracking the flagellar waveform. Although computer-aided sperm analysis (CASA) options are becoming more widespread, the gold standard for clinical semen analysis requires trained laboratory staff. In this review we characterise the key attitudes towards the use of CASA and set out areas in which CASA should, and should not, be used and improved. We provide an overview of the current CASA landscape, discussing clinical uses as well as potential areas for the clinical translation of existing research technologies. Finally, we discuss where we see potential for the future of CASA, and how the integration of mathematical modelling and new technologies, such as automated flagellar tracking, may open new doors in clinical semen analysis.

scholarly journals Genome sequencing in the clinic: the past, present, and future of genomic medicine

2018 ◽  
Vol 50 (8) ◽  
pp. 563-579 ◽  
Author(s):  
Jeremy W. Prokop ◽  
Thomas May ◽  
Kim Strong ◽  
Stephanie M. Bilinovich ◽  
Caleb Bupp ◽  
...  
Keyword(s):  
Precision Medicine ◽  
Genome Sequencing ◽  
Clinical Setting ◽  
Structural Changes ◽  
New Technologies ◽  
Cancer Genomics ◽  
Genomic Medicine ◽  
Driver Gene ◽  
The Past ◽  
The Future

Genomic sequencing has undergone massive expansion in the past 10 yr, from a rarely used research tool into an approach that has broad applications in a clinical setting. From rare disease to cancer, genomics is transforming our knowledge of biology. The transition from targeted gene sequencing, to whole exome sequencing, to whole genome sequencing has only been made possible due to rapid advancements in technologies and informatics that have plummeted the cost per base of DNA sequencing and analysis. The tools of genomics have resolved the etiology of disease for previously undiagnosable conditions, identified cancer driver gene variants, and have impacted the understanding of pathophysiology for many diseases. However, this expansion of use has also highlighted research’s current voids in knowledge. The lack of precise animal models for gene-to-function association, lack of tools for analysis of genomic structural changes, skew in populations used for genetic studies, publication biases, and the “Unknown Proteome” all contribute to voids needing filled for genomics to work in a fast-paced clinical setting. The future will hold the tools to fill in these voids, with new data sets and the continual development of new technologies allowing for expansion of genomic medicine, ushering in the days to come for precision medicine. In this review we highlight these and other points in hopes of advancing and guiding precision medicine into the future for optimal success.

Allocating Resources for New Technology within Entrepreneurial Firms

2003 ◽  
Vol 4 (1) ◽  
pp. 5-12 ◽  
Author(s):  
Jill Kickul ◽  
Elizabeth Belgio ◽  
Tim Hanna
Keyword(s):  
Structural Equation Modelling ◽  
Structural Equation ◽  
New Technologies ◽  
New Technology ◽  
Entrepreneurial Firms ◽  
The Past ◽  
Equation Modelling ◽  
Risk Of Failure ◽  
The Future ◽  
The Relationship

This study seeks to determine the influence of the underlying factors and barriers that may inhibit the implementation of new technological investments by entrepreneurial firms. These factors and barriers may include the potential costs, risk of failure, low technological awareness, lack of an outside organization to facilitate development, lack of approachable organizations with which to form partnerships, and lack of contact with other organizations that have implemented technology successfully. Using structural equation modelling (LISREL VIII), results revealed that the value and importance that entrepreneurs placed on learning and adopting new technologies, in addition to the risk of failure, mediated the relationship between many of these barriers and the firms' technological investment during the past year, as well as their willingness to spend on new technology in the future.

scholarly journals Past music, future music: Technology and music institutions in the 20th century

New Sound ◽  
2016 ◽  
pp. 53-64
Author(s):  
Marija Maglov
Keyword(s):  
20Th Century ◽  
New Technologies ◽  
Music Technology ◽  
New Music ◽  
Music Practice ◽  
The Past ◽  
Pierre Boulez ◽  
The Future ◽  
Progressive Technology ◽  
Point Of Departure

In his text Technology and the Composer Pierre Boulez writes about new technologies that emerged in the 20th century, primarily created for the purposes of music recording and reproduction, but also established as a means of innovation in electronic and electro-acoustic music practice. Boulez points to two directions where technology and music are in question: conservative historicism and progressive technology, enabling the development of new music material and innovation. By using Boulez's text(s) as a point of departure, the author considers the roles those new technologies had in the development of some musical institutions and questions how institutionalized discourse molds ideas on the roles music technology should have. The aim of the paper is to discuss how the music of the past was 'conserved' and how the music of the future was created in particular types of music institutions thanks to new technological possibilities.

The Future of Audit in Light of Technological Changes

2021 ◽  
pp. 228-249
Author(s):  
Sanja Sever Mališ ◽  
Lajoš Žager ◽  
Mateja Brozović
Keyword(s):  
Financial Reporting ◽  
New Technologies ◽  
Financial Statements ◽  
Technological Changes ◽  
External Audit ◽  
The Past ◽  
The Future ◽  
New Challenges ◽  
The Way

External audit of financial statements plays a key role in achieving transparent financial reporting, since its purpose is to provide reasonable assurance that the presented financial statements are free of material misstatements due to fraud or error. In the process of fulfilling this role, auditors must be adaptable, especially when it comes to technological advancements. This chapter explains the effect that new technologies have on audit of financial statements. In addition to summarizing the technological changes that impacted the audit profession in the past and therefore introduced new generations of audit, the authors have identified issues and challenges in the way the audit is currently performed. Some of the new technologies that are discussed in this chapter have the potential to mitigate these issues. However, new challenges and risks may be introduced with accepting these technologies in the process of financial reporting and auditing.

Augmenting Secondary Education with Advanced Microscopy

2011 ◽  
Vol 19 (3) ◽  
pp. 48-52 ◽  
Author(s):  
Craig Queenan ◽  
Alyssa Calabro ◽  
David Becker
Keyword(s):  
High School ◽  
New World ◽  
New Technologies ◽  
School Level ◽  
High School Level ◽  
China And India ◽  
The Past ◽  
State Of The Union ◽  
Bergen County ◽  
The Future

In his 2011 State of the Union address, President Barack Obama echoed the sentiments of this nation's leaders for the past twenty years when he stated, “Nations like China and India realized…they could compete in this new world. So they started educating their children earlier and longer, with greater emphasis on math and science. They're investing in research and new technologies…. Maintaining our leadership in research and technology is crucial to America's success. But if we want to win the future—if we want innovation to produce jobs in America and not overseas—then we also have to win the race to educate our kids.” The Bergen County Academies (BCA) in Hackensack, NJ, is attempting to do just that: invest in research and technology at the high school level in order to expose students to real world opportunities and applications they will experience in the future.

scholarly journals What Do The Single Technology Appraisals of The Past Tell US About Fast-Tracking The Most Cost-Effective New Technologies In The Future?

2017 ◽  
Vol 20 (9) ◽  
pp. A410
Author(s):  
A Boland ◽  
R Houten ◽  
C Carroll ◽  
E Kaltenthauer ◽  
R Dickson
Keyword(s):  
New Technologies ◽  
Cost Effective ◽  
Fast Tracking ◽  
The Past ◽  
The Future

Human rights: between the past and the future

2021 ◽  
Author(s):  
Tat'yana Vasil'eva ◽  
Anton Aleksenko ◽  
Nataliya Varlamova ◽  
Nataliya Voronina ◽  
Anna Dzyubak ◽  
...  
Keyword(s):  
Human Rights ◽  
Political Science ◽  
Constitutional Law ◽  
New Technologies ◽  
Law Schools ◽  
The Past ◽  
The Future ◽  
Theory Of Law

The monograph presents an analysis of various doctrinal interpretations of human rights and national practices of their implementation. Special attention is paid to the universalization of approaches to ensuring human rights and the development of effective mechanisms for their protection, as well as the search for answers to modern challenges and threats to human rights caused by globalization, the emergence of new technologies and the COVID-19 pandemic. For researchers, teachers, postgraduates and students of law schools, specialists in the field of theory of law and state, international and constitutional law, political science, as well as for anyone interested in ensuring human rights.

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