scholarly journals Variation in NGFB is associated with primary affective disorders in women

2011 ◽  
Vol 156 (4) ◽  
pp. 401-412 ◽  
Author(s):  
Donghong Cui ◽  
Huiping Zhang ◽  
Bao-Zhu Yang ◽  
Jennifer B. Listman ◽  
Dawei Li ◽  
...  
Keyword(s):  
Affective Disorders ◽  
Primary Affective Disorders

Abnormal beta-endorphin and beta-lipotropin responses to TRH and LRH administration in primary and secondary affective disorders

1986 ◽  
Vol 112 (4) ◽  
pp. 481-486 ◽  
Author(s):  
E. Brambilla ◽  
F. Petraglia ◽  
F. Facchinetti ◽  
A. R. Genazzani
Keyword(s):  
Plasma Levels ◽  
Affective Disorders ◽  
Anterior Pituitary ◽  
Pituitary Hormone ◽  
Acute Administration ◽  
Beta Endorphin ◽  
Anterior Pituitary Hormone ◽  
Saline Administration ◽  
Hormone Responses ◽  
Primary Affective Disorders

Abstract. Anomalous anterior pituitary hormone responses to acute administration of TRH and LRH have previously been observed in patients with primary affective disorders (PAD), with TRH eliciting GH, FSH and LH rises, and LRH eliciting GH and Prl rises. We examined whether the same unusual responses were present also for beta-endorphin (β-EP) and beta-lipotropin (β-LPH) in 15 PAD patients, in 9 patients with secondary affective disorders (SAD), and in 7 controls. TRH (500 ug iv) elicited rises of β-EP plasma levels in 5 PAD and 2 SAD patients, and of β-LPH in 4 PAD and 3 SAD patients. LRH (150 ug iv) elicited rises of plasma β-EP levels in 2 PAD and 2 SAD patients, and of β-LPH in 5 PAD and 2 SAD patients. No rises of β-EP and β-LPH plasma levels were observed in PAD patients after saline administration, nor in the controls after TRH, LRH or saline administration.

Life Events and Primary Affective Disorders

1996 ◽  
Vol 169 (2) ◽  
pp. 160-166 ◽  
Author(s):  
D. Pardoen ◽  
F. Bauwens ◽  
M. Dramaix ◽  
A. Tracy ◽  
C. Genevrois ◽  
...  
Keyword(s):  
Life Events ◽  
Affective Disorders ◽  
Causal Association ◽  
Marital Problems ◽  
Psychiatric Status ◽  
Healthy Control ◽  
One Year ◽  
Primary Affective Disorders ◽  
Bipolar Patients ◽  
Study Participants

BackgroundUnipolar and bipolar patients with a chronic illness pattern were investigated to determine whether they experienced a higher number of life events prior to the onset of recurrent affective episodes.MethodThe study participants consisted of 27 recovered bipolar patients, 24 recovered unipolar patients and 26 healthy control subjects. Life events and psychiatric status were assessed by bimonthly interviews over the period of one year using the Inventory for Recent Life Events and the Research Diagnostic Criteria.ResultsIn both unipolar and bipolar patients, analyses revealed no significant differences in the number of life events experienced, irrespective of whether the patients had presented with a depressive episode of at least minor intensity during the study (all P > 0.1). Specifically, an increase in marital problems was observed in bipolar patients prior to the onset of recurrent hypomanic and manic episodes (P=0.06).ConclusionThe causal association between life events and the onset of depression, shown to be relevant in non-chronically depressed subjects, does not apply in chronic affective disorders. In addition, our results suggest that marital events have an impact on the onset of recurrent hypomanic and manic episodes.

Neuroleptic Malignant Syndrome: Life-Threatening Complication of Neuroleptic Treatment in Adolescents with Affective Disorder

PEDIATRICS ◽  
1991 ◽  
Vol 87 (2) ◽  
pp. 235-239
Author(s):  
Paramjit T. Joshi ◽  
Joseph A. Capozzoli ◽  
Joseph T. Coyle
Keyword(s):  
Risk Factor ◽  
Affective Disorder ◽  
Neuroleptic Malignant Syndrome ◽  
Affective Disorders ◽  
Pediatric Population ◽  
Psychotic Symptoms ◽  
Neuroleptic Treatment ◽  
Life Threatening ◽  
Life Threatening Complication ◽  
Primary Affective Disorders

Neuroleptic malignant syndrome (NMS) is an uncommon, potentially fatal side effect of neuroleptic treatment characterized by hyperthermia, rigidity, rhabdomyolysis, and delerium. In recent clinical studies of adults it was suggested that affective disorder is a risk factor for the development of neuroleptic malignant syndrome. The cases of two adolescents with neuroleptic malignant syndrome who were treated with neuroleptic therapy because of psychotic symptoms in association with primary affective disorders are reported. The occurrence of these cases, as well as the observations in adults, suggests that attention to the primary psychiatric diagnosis is important in neuroleptic usage and that physicians should be vigilant to the occurrence of neuroleptic malignant syndrome in the pediatric population.

Assortative mating among in-patients with primary affective disorder

1982 ◽  
Vol 12 (4) ◽  
pp. 753-764 ◽  
Author(s):  
Kathleen Ries Merikangas ◽  
Duane G. Spiker
Keyword(s):  
Assortative Mating ◽  
Affective Disorders ◽  
Psychiatric Illness ◽  
Marital Interaction ◽  
Affective Illness ◽  
First Degree Relatives ◽  
Diagnostic Concordance ◽  
Primary Affective Disorders ◽  
Bipolar Patients ◽  
High Degree

SynopsisAssortative mating among 56 married in-patients with primary affective disorders and their spouses was studied by determining the prevalence of psychiatric illness among the spouses by means of direct interviews and standardized diagnostic criteria. A high degree of assortative mating among both male and female patients was observed for total psychiatric illness, broad spectrum affective illness and major depression. A significantly higher prevalence of psychiatric and affective illness was found among the first-degree relatives of the ill spouses when compared with the first-degree relatives of the well spouses. There was a high degree of diagnostic concordance between the patients and spouses for both affective illness and alcoholism, with a higher degree of assortative mating among bipolar patients than among unipolar patients. The finding in this study of an increased prevalence of psychiatric disorder in the first-degree relatives of the ill spouses would support the hypothesis that there is a tendency for individuals with a predisposition to psychiatric illness to marry, rather than the existence of a marital interaction which causes an increased concordance for psychiatric illness.

Primary Affective Disorders and HLA Antigens

1978 ◽  
Vol 11 (2) ◽  
pp. 190-191 ◽  
Author(s):  
A. Májský ◽  
P. Zvolský ◽  
M. Dvořáková
Keyword(s):  
Affective Disorders ◽  
Hla Antigens ◽  
Primary Affective Disorders

Recurrent Course of Primary Affective Disorders: Explanation by the Theory of Biorhythms

1985 ◽  
Vol 13 (1-2) ◽  
pp. 17-22 ◽  
Author(s):  
P. Zvolský ◽  
E. Veselá ◽  
P. Bošek
Keyword(s):  
Affective Disorders ◽  
Primary Affective Disorders

The Relationship between Agoraphobia and Primary Affective Disorders

1979 ◽  
Vol 24 (4) ◽  
pp. 317-322 ◽  
Author(s):  
R.C. Bowen ◽  
J. Kohout
Keyword(s):  
Affective Disorder ◽  
General Hospital ◽  
Affective Disorders ◽  
Psychiatric Practice ◽  
Published Data ◽  
Primary Affective Disorders ◽  
Clinical Records ◽  
The Relationship

Detailed clinical records were kept on a series of 55 agoraphobic patients who presented to a general hospital psychiatric practice over a 3 year period. A review of the records revealed that 91% of these patients were diagnosed as suffering from a unipolar or bipolar primary affective disorder. The anxiety and phobic symptoms tended to mask the presence of the affective disorder. This observation is consistent with most of the published data on the agoraphobic syndrome. It could also explain the inconsistent effects of treatment of agoraphobia compared with simple phobias. The possible biological and psychological connections between primary affective disorders and the agoraphobic syndrome are discussed.

Age of onset in primary affective disorders: Epidemiological and genetic studies

1996 ◽  
Vol 6 ◽  
pp. 251
Author(s):  
L Ravindran ◽  
M Alda ◽  
P Grof ◽  
E Grof ◽  
P Cavazzoni ◽  
...  
Keyword(s):  
Affective Disorders ◽  
Age Of Onset ◽  
Genetic Studies ◽  
Primary Affective Disorders

Neuroendocrine and psychopathological measures in anorexia nervosa: Resemblances to primary affective disorders

1985 ◽  
Vol 16 (2) ◽  
pp. 165-176 ◽  
Author(s):  
Francesca Brambilla ◽  
Franco Cavagnini ◽  
Cecilia Invitti ◽  
Franco Poterzio ◽  
Mario Lampertico ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Affective Disorders ◽  
Primary Affective Disorders
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