No interaction between the serotonin transporter polymorphism (5-HTTLPR) and childhood adversity or recent stressful life events on symptoms of depression: Results from two community surveys

2007 ◽  
Vol 144B (4) ◽  
pp. 561-565 ◽  
Author(s):  
P. Chipman ◽  
A.F. Jorm ◽  
M. Prior ◽  
A. Sanson ◽  
D. Smart ◽  
...  
Keyword(s):  
Life Events ◽  
Serotonin Transporter ◽  
Stressful Life Events ◽  
Childhood Adversity ◽  
Stressful Life ◽  
Community Surveys ◽  
Symptoms Of Depression ◽  
Serotonin Transporter Polymorphism

scholarly journals Interaction between serotonin transporter polymorphism (5-HTTLPR) and stressful life events in adolescents' trajectories of anxious/depressed symptoms.

2012 ◽  
Vol 48 (5) ◽  
pp. 1463-1475 ◽  
Author(s):  
Isaac T. Petersen ◽  
John E. Bates ◽  
Jackson A. Goodnight ◽  
Kenneth A. Dodge ◽  
Jennifer E. Lansford ◽  
...  
Keyword(s):  
Life Events ◽  
Serotonin Transporter ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Serotonin Transporter Polymorphism ◽  
Depressed Symptoms

scholarly journals Stressful life events and the serotonin transporter gene ( 5-HTT ) in recurrent clinical depression

2012 ◽  
Vol 136 (1-2) ◽  
pp. 189-193 ◽  
Author(s):  
Helen L. Fisher ◽  
Sarah Cohen-Woods ◽  
Georgina M. Hosang ◽  
Rudolf Uher ◽  
Georgia Powell-Smith ◽  
...  
Keyword(s):  
Life Events ◽  
Serotonin Transporter ◽  
Stressful Life Events ◽  
Clinical Depression ◽  
Serotonin Transporter Gene ◽  
Stressful Life ◽  
Transporter Gene

scholarly journals Psychological Distress and Stressful Life Events in Pediatric Complex Regional Pain Syndrome

2015 ◽  
Vol 20 (4) ◽  
pp. 189-194 ◽  
Author(s):  
Julia Wager ◽  
Hannah Brehmer ◽  
Gerrit Hirschfeld ◽  
Boris Zernikow
Keyword(s):  
Abdominal Pain ◽  
Life Events ◽  
Stressful Life Events ◽  
Pain Treatment ◽  
Pain Syndrome ◽  
Stressful Life ◽  
Primary Headaches ◽  
Depression And Anxiety ◽  
Functional Abdominal Pain ◽  
Symptoms Of Depression

BACKGROUND: There is little knowledge regarding the association between psychological factors and complex regional pain syndrome (CRPS) in children. Specifically, it is not known which factors precipitate CRPS and which result from the ongoing painful disease.OBJECTIVES: To examine symptoms of depression and anxiety as well as the experience of stressful life events in children with CRPS compared with children with chronic primary headaches and functional abdominal pain.METHODS: A retrospective chart study examined children with CRPS (n=37) who received intensive inpatient pain treatment between 2004 and 2010. They were compared with two control groups (chronic primary headaches and functional abdominal pain; each n=37), who also received intensive inpatient pain treatment. Control groups were matched with the CRPS group with regard to admission date, age and sex. Groups were compared on symptoms of depression and anxiety as well as stressful life events.RESULTS: Children with CRPS reported lower anxiety and depression scores compared with children with abdominal pain. A higher number of stressful life events before and after the onset of the pain condition was observed for children with CRPS.CONCLUSIONS: Children with CRPS are not particularly prone to symptoms of anxiety or depression. Importantly, children with CRPS experienced more stressful life events than children with chronic headaches or abdominal pain. Prospective long-term studies are needed to further explore the potential role of stressful life events in the etiology of CRPS.

scholarly journals Threats to Belonging—Stressful Life Events and Mental Health Symptoms in Aging Men—A Longitudinal Cohort Study

2020 ◽  
Vol 11 ◽  
Author(s):  
Jutta Lindert ◽  
Lewina O. Lee ◽  
Marc G. Weisskopf ◽  
Martin McKee ◽  
Susanne Sehner ◽  
...  
Keyword(s):  
Cohort Study ◽  
Life Events ◽  
Life Stress ◽  
Stressful Life Events ◽  
Adult Life ◽  
Stressful Life ◽  
Symptoms Of Depression ◽  
The Past ◽  
Aging Men ◽  
The Impact

Objectives: Stressful life events, especially relationship events, are frequent in adult life. We investigated the impact of a variety of stressful life events on symptoms of depression, anxiety, and hostility.Methods: We analyzed data from a large prospective cohort study of men (n = 1,437) in the Boston area (assessed in 1985, 1988, and 1991). Main outcomes were measures of depression, anxiety and hostility symptoms. We used the Elders Life Stress Inventory (ELSI) to measure stressful life events in the past 12 months and examine their association with symptoms of depression, anxiety and hostility. First, we analyzed the association of stressful life events with symptom changes; second, we categorized stressful life events into finance/work, health, relationships, loss, living situations events; and third, we estimated the specific association between relationship events and depression, anxiety and hostility symptoms using multilevel models.Results: The most frequent stressful life events were health, relationship, and financial events. Depression, anxiety, and hostility symptoms were relatively stable among men who did not experience these life events. However, those who reported life events in the past 12 months had a greater increase in symptoms of depression (+0.05; 95% CI: 0.01 to 0.10) and of hostility (+0.05; 95% CI: 0.01 to 0.09) than those who did not. Additionally, we found a significant decrease in hostility (−0.05; 95% CI: −0.08 to −0.01) in those experiencing no life events.Conclusion: Relationship events were more important than any other type of events, and were significantly associated with increased depression and hostility in aging men. Although the effects were small, the results point to a need to understand better the impact of relationships on psychopathology in the aging population.

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