The influence of four serotonin-related genes on decision-making in suicide attempters

2007 ◽  
Vol 144B (5) ◽  
pp. 615-624 ◽  
Author(s):  
Fabrice Jollant ◽  
Catherine Buresi ◽  
Sébastien Guillaume ◽  
Isabelle Jaussent ◽  
Frank Bellivier ◽  
...  
2005 ◽  
Vol 162 (2) ◽  
pp. 304-310 ◽  
Author(s):  
Fabrice Jollant ◽  
Frank Bellivier ◽  
Marion Leboyer ◽  
Bernard Astruc ◽  
Stéphane Torres ◽  
...  

2011 ◽  
Vol 26 (S2) ◽  
pp. 2164-2164 ◽  
Author(s):  
P. Courtet ◽  
M. Wyart ◽  
I. Jaussent ◽  
K. Ritchie ◽  
F. Jollant

Suicide is a major public health concern, especially for older adults, who have higher rates of completed suicide than any other age group in most countries of the world. However, understanding suicidal behaviour remains a challenging task particularly among the elders who have been poorly studied. Decision making has been recently found to be altered in suicide attempters under 65.To test wether decision making would be a neuropsychological trait of vulnerability to suicidal behaviours, the authors used the Iowa Gambling Task to investigate normothymic non demented elders with a history of suicidal behaviour (N = 35) and compared it to decision making in non suicide attempters with a past history of depression (N = 52) and comparison subjects (N = 43). The data also were compared to those of similar groups of younger normothymic subjects. Moreover, the old suicidal patients were assessed according to the age at the onset of suicidal behaviour (before or after 60).Old suicide attempters did not significantly differ from the other aged groups and according to the age of first suicidal behaviour. Old suicide attempters presented better performances than that of younger suicidal patients.Vulnerability to suicidal behaviour in older people may proceed from cognitive processes which are different from the ones involved in suicidal vulnerability of younger subjects. These results are preliminary and further studies are needed to explore vulnerability cognitive patterns to suicide among elders.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 621-622
Author(s):  
Katalin Szanto

Abstract Social motivations to engage in suicide in late life frequently include interpersonal problems and escape from perceived defeat. To describe decision making patterns that may contribute to the catastrophic decision to take one’s life, we used behavioral experiments and assessed cognitive abilities and personality traits. We found that neuroticism, low extraversion, and low conscientiousness characterize older adults who contemplate suicide and those with low-lethality suicide attempts. Employing a novel version of the Ultimatum Game, we measured empathy’s moderating response to social conflict. We found that older suicide attempters were less influenced by empathy scenarios, indicating that a failure to integrate others’ emotions into decisions may undermine social deterrents to suicide. To simulate social status loss, we used a newly developed, competitive task (rigged toward primarily losing outcomes) paired with performance ranking. We found that suicide attempters, especially those with narcissistic traits, engaged in more excessive compensatory behaviors than older non-attempters.


2021 ◽  
Vol 12 ◽  
Author(s):  
Lingling Wang ◽  
Jingmin Li ◽  
Hailing Liu ◽  
Zhongpeng Wang ◽  
Li Yang ◽  
...  

Impaired decision-making has been observed in suicide attempters during the Iowa Gambling Task (IGT). Decision-making performance is influenced by somatic markers and explicit knowledge, but it is still unclear of the influencing role on decision-making performance in suicidal individuals. We aimed to investigate whether there is a decision-making deficit in suicide attempters, suicide ideators, as well as the distinct roles of somatic markers and explicit knowledge wherein. Thirteen suicide attempters, 23 suicide ideators, and 19 healthy controls performed the IGT. Both somatic markers (by the skin conductance responses, SCRs) and explicit knowledge (by the subjective experience rating and a list of questions) were recorded. No significant differences were found among the three groups on IGT performance, explicit knowledge, and anticipatory SCRs. IGT Performance of suicide attempters was positively correlated with explicit knowledge index while behavior performance was positively associated with the SCRs in healthy controls. These results indicate that the suicide attempters seem to apply a compensatory strategy by mostly utilizing explicit knowledge to perform normally as healthy controls in the IGT.


2009 ◽  
Vol 19 ◽  
pp. S355
Author(s):  
A. Szkaliczki ◽  
E. Krivek ◽  
B. Ando ◽  
A. Fehér ◽  
Z. Janka ◽  
...  

2013 ◽  
Vol 47 (2) ◽  
pp. 259-265 ◽  
Author(s):  
Sebastien Guillaume ◽  
Nader Perroud ◽  
Fabrice Jollant ◽  
Isabelle Jaussent ◽  
Emilie Olié ◽  
...  

2015 ◽  
Vol 25 (2) ◽  
pp. 109-113 ◽  
Author(s):  
John P Ackerman ◽  
Sandy M McBee-Strayer ◽  
Kristen Mendoza ◽  
Jack Stevens ◽  
Arielle H Sheftall ◽  
...  

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