p75NTR gene and suicide attempts in young adults with a history of childhood-onset mood disorder

2007 ◽  
Vol 144B (5) ◽  
pp. 696-700 ◽  
Author(s):  
S. McGregor ◽  
J. Strauss ◽  
N. Bulgin ◽  
V. De Luca ◽  
C.J. George ◽  
...  
Crisis ◽  
2016 ◽  
Vol 37 (4) ◽  
pp. 265-270 ◽  
Author(s):  
Meshan Lehmann ◽  
Matthew R. Hilimire ◽  
Lawrence H. Yang ◽  
Bruce G. Link ◽  
Jordan E. DeVylder

Abstract. Background: Self-esteem is a major contributor to risk for repeated suicide attempts. Prior research has shown that awareness of stigma is associated with reduced self-esteem among people with mental illness. No prior studies have examined the association between self-esteem and stereotype awareness among individuals with past suicide attempts. Aims: To understand the relationship between stereotype awareness and self-esteem among young adults who have and have not attempted suicide. Method: Computerized surveys were administered to college students (N = 637). Linear regression analyses were used to test associations between self-esteem and stereotype awareness, attempt history, and their interaction. Results: There was a significant stereotype awareness by attempt interaction (β = –.74, p = .006) in the regression analysis. The interaction was explained by a stronger negative association between stereotype awareness and self-esteem among individuals with past suicide attempts (β = –.50, p = .013) compared with those without attempts (β = –.09, p = .037). Conclusion: Stigma is associated with lower self-esteem within this high-functioning sample of young adults with histories of suicide attempts. Alleviating the impact of stigma at the individual (clinical) or community (public health) levels may improve self-esteem among this high-risk population, which could potentially influence subsequent suicide risk.


PEDIATRICS ◽  
2007 ◽  
Vol 120 (Supplement 3) ◽  
pp. S128.1-S128
Author(s):  
Timothy Andrews ◽  
James R. Banks

1995 ◽  
Vol 167 (5) ◽  
pp. 679-682 ◽  
Author(s):  
Patrick F. Sullivan ◽  
Cynthia M. Bulik ◽  
Frances A. Carter ◽  
Peter R. Joyce

BackgroundChildhood sexual abuse (CSA) is found to have occurred to a substantial minority of women with bulimia nervosa. Its clinical significance is unclear.MethodWe studied 87 bulimic women in a clinical trial. Structured interviews determined the presence of CSA, DSM–III–R disorders, global functioning, and depressive and bulimic symptoms.ResultsForty-four per cent reported a history of CSA. Bulimic women with CSA reported earlier onset of bulimia, greater depressive symptoms, worse global functioning and more suicide attempts, and were more likely to meet criteria for bipolar II disorder, alcohol and drug dependence, conduct disorder and avoidant personality disorder.ConclusionsAlthough those with CSA had greater comorbidity, it was not an important modifier of bulimic symptoms.


2020 ◽  
pp. 088626052095864
Author(s):  
Sarah Love ◽  
Sharon E. Robinson Kurpius

This study examined whether a history of childhood sexual abuse (CSA), attachment to mother, father, and friends, and mattering were related to the coping behaviors of 171 male and 85 female, ethnically diverse, low-income, young adults. The 74 survivors of CSA reported lower attachment to father and less mattering to parents than did the 97 who reported no abuse. Compared to male survivors, female survivors reported greater use of problem-focused coping and also perceived their abuse experience, particularly the use of force, as having a more negative impact on them. Stronger attachment to mother and to friends predicted more positive problem-focused coping. Mattering to friends moderated the relation between CSA history and problem-focused coping, with the CSA survivors who reported the highest mattering to friends also using the most problem-focused coping strategies. The role of attachment and mattering in problem-focused coping among young adults, especially those with a CSA history, is discussed.


2019 ◽  
Vol 5 (6) ◽  
pp. e362-e364
Author(s):  
Terry Shin ◽  
Jay R. Shapiro

Objective: This case highlights the value of genetic screening for idiopathic osteoporosis with recurrent fractures. Methods: Case report and review of the literature. Results: A 52-year-old Caucasian female with idiopathic osteoporosis with recurrent fractures was identified with a heterozygous low-density lipoprotein receptor related protein 5 (LRP5) mutation. Conclusion: This case highlights the variability in clinical expression of LRP5 polymorphisms and suggests that standard treatment in cases of recurrent fracture may be ineffective.


2005 ◽  
Vol 116 (6) ◽  
pp. 1213-1219 ◽  
Author(s):  
S LIMB ◽  
K BROWN ◽  
R WOOD ◽  
R WISE ◽  
P EGGLESTON ◽  
...  

1991 ◽  
Vol 9 ◽  
pp. S318
Author(s):  
Jean-Pierre Salles ◽  
Philippe Barthe ◽  
Francois Begasse ◽  
François Bouissou ◽  
Hugues Chap ◽  
...  

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