ProtocadherinX/Y, a candidate gene-pair for schizophrenia and schizoaffective disorder: A DHPLC investigation of genomic sequence

2004 ◽  
Vol 129B (1) ◽  
pp. 1-9 ◽  
Author(s):  
Maria Giouzeli ◽  
Nic A. Williams ◽  
Lorne J. Lonie ◽  
Lynn E. DeLisi ◽  
Timothy J. Crow
Keyword(s):  
Candidate Gene ◽  
Schizoaffective Disorder ◽  
Gene Pair ◽  
Genomic Sequence

scholarly journals Characterization of genomic DNA sequence of the candidate gene for FB_Mfu10 associated with fire blight resistance in Malus species

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Ofere Francis Emeriewen ◽  
Henryk Flachowsky ◽  
Andreas Peil
Keyword(s):  
Candidate Gene ◽  
Transgenic Line ◽  
Fire Blight ◽  
Gene Sequence ◽  
Genomic Sequence ◽  
Blight Resistance ◽  
Resistance Locus ◽  
Native Promoter ◽  
Exon 1

Abstract Objective The proposed candidate gene underlying the Malus fusca fire blight resistance locus on chromosome 10 was previously predicted to possess 880 amino acids and 8 exons. Eight base pair (8 bp) insertion/deletion in the first exon potentially distinguished resistant genotypes from susceptible ones. This study aimed at analyzing the candidate gene sequence in another set of original resistant and susceptible progeny, characterizing the sequence in a transgenic line transformed with the candidate gene under its own native promoter, as well as deciphering the potential genomic differences between this candidate gene and its homolog in the ‘Golden Delicious’ doubled haploid genome (GDDH13). Results Sequences of amplicons of part of the candidate gene amplified in two progenies that showed resistant and susceptible fire blight phenotypes, confirmed the 8 bp insertion that distinguishes susceptible and resistant progenies. The transgenic line was positive for the candidate gene sequence, confirming a successful transfer into the background of apple cultivar ‘Pinova’, and possessed the same genomic sequence as the progeny with a resistant phenotype. Sequence analysis showed that the homolog gene on GDDH13 possesses a significant 18 bp deletion in exon 1 leading to a difference of 15 amino acid from the protein sequence of the candidate gene.

A candidate gene study in predicted severe acute pancretitis

2001 ◽  
Vol 120 (5) ◽  
pp. A468-A468 ◽  
Author(s):  
G GALLAGHER ◽  
P CHONG ◽  
J ESKDALE ◽  
A COOK ◽  
S CAIMS ◽  
...  
Keyword(s):  
Candidate Gene ◽  
Candidate Gene Study ◽  
Gene Study ◽  
Acute Pancretitis

The cholesterol transporter Abcg1, a candidate gene for obesity: deletion of Abcg1 in mice corrects diet-induced insulin resistance

2007 ◽  
Vol 2 (S 1) ◽  
Author(s):  
J Buchmann ◽  
C Meyer ◽  
S Neschen ◽  
R Kluge ◽  
R Wehr ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Candidate Gene

GIRK2 – A novel candidate gene for attention deficit hyperactivity disorder

2007 ◽  
Vol 40 (05) ◽  
Author(s):  
C Röser ◽  
TJ Renner ◽  
S Walitza ◽  
A Dempfle ◽  
T Nguyen ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Candidate Gene ◽  
Attention Deficit ◽  
Hyperactivity Disorder

Turner Mosaicism and Schizoaffective Disorder

2014 ◽  
pp. 1-8
Author(s):  
Katherine Backes ◽  
Tiffany Christian ◽  
Gaurava Agarwal
Keyword(s):  
Schizoaffective Disorder

Insight: Demographic Differences and Associations with One-Year Outcome in Schizophrenia and Schizoaffective Disorder

2010 ◽  
Vol 4 (3) ◽  
pp. 169-175 ◽  
Author(s):  
Benjamin Wiffen ◽  
Jonathan Rabinowitz ◽  
W. Fleischhacker ◽  
Anthony David
Keyword(s):  
Schizoaffective Disorder ◽  
Demographic Differences ◽  
One Year
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