Risk factors for primary congenital glaucoma in the National Birth Defects Prevention Study

2019 ◽  
Author(s):  
Nina E. Forestieri ◽  
Tania A. Desrosiers ◽  
Sharon F. Freedman ◽  
Arthur S. Aylsworth ◽  
Kristin Voltzke ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Defects ◽  
Congenital Glaucoma ◽  
Prevention Study ◽  
Primary Congenital Glaucoma

Maternal diet as a risk factor for primary congenital glaucoma and defects of the anterior segment of the eye in the National Birth Defects Prevention Study

2020 ◽  
Vol 112 (6) ◽  
pp. 503-514 ◽  
Author(s):  
Kristin J. Moore ◽  
Suzan L. Carmichael ◽  
Nina E. Forestieri ◽  
Tania A. Desrosiers ◽  
Robert E. Meyer ◽  
...  
Keyword(s):  
Risk Factor ◽  
Birth Defects ◽  
Maternal Diet ◽  
Anterior Segment ◽  
Congenital Glaucoma ◽  
Prevention Study ◽  
Primary Congenital Glaucoma

Cataract extraction in patients with primary congenital glaucoma

2019 ◽  
Vol 30 (3) ◽  
pp. 525-532
Author(s):  
Laura Morales-Fernández ◽  
José María Martínez-de-la-Casa ◽  
Blanca Benito-Pascual ◽  
Federico Saénz-Francés ◽  
Enrique Santos-Bueso ◽  
...  
Keyword(s):  
Risk Factors ◽  
Visual Acuity ◽  
Intraocular Pressure ◽  
Cataract Extraction ◽  
Hazard Ratio ◽  
High Rate ◽  
Congenital Glaucoma ◽  
Primary Congenital Glaucoma ◽  
Corneal Decompensation

Objective: To assess incidence and risk factors of cataract extraction in patients with primary congenital glaucoma, surgical outcome, and complications. Material and method: Retrospective cohort study, in which 108 patients with primary congenital glaucoma were included. Data collected were need for cataract extraction and at what age, intraocular pressure at diagnosis of primary congenital glaucoma, required antiglaucomatous surgeries, possible mutation in the CYP1B1 gene, and final visual acuity. Among the patients who required cataract extraction were visual acuity, intraocular pressure, and complications, evaluated preoperatively and postoperatively. The data were analysed with STATA. Results: A total of 198 eyes of 108 patients were included, with a median follow-up of 8 years (range: 5–53). In all, 32 eyes (16.2%) of 24 patients (22%) required cataract extraction. The median age for cataract extraction was 12.94 years (interquartile range: 2.42–22). The main identified risk factors associated with cataract extraction were antiglaucomatous surgeries (hazard ratio 1.48, p < 0.001) and valvular implant (hazard ratio 2.78, p < 0.001). Lens was implanted in 30/32 eyes and the main complications were intraocular pressure decontrol ( n = 13), capsular fibrosis ( n = 7), corneal decompensation ( n = 4), lens subluxation ( n = 4), and endophthalmitis ( n = 1). Visual acuity improvement was observed after cataract extraction in 66.67% of eyes. Conclusions: There is a high incidence of cataract surgery in patients with primary congenital glaucoma, but generally outside of pediatric age. A greater risk of cataract extraction was identified in those patients with a greater number of antiglaucomatous surgeries, especially after valvular implantation. Despite the high rate of complications related to cataract extraction in primary congenital glaucoma, good visual improvement was observed after surgery.

103: Risk factors for infantile cataracts, national birth defects prevention study, 2000-2004

2009 ◽  
Vol 13 (1) ◽  
pp. e26
Author(s):  
Sasapin G. Prakalapakorn ◽  
Sonja A. Rasmussen ◽  
Scott R. Lambert ◽  
Margaret A. Honein
Keyword(s):  
Risk Factors ◽  
Birth Defects ◽  
Prevention Study

Risk factors for isolated biliary atresia, National Birth Defects Prevention Study, 1997–2002

2007 ◽  
Vol 143A (19) ◽  
pp. 2274-2284 ◽  
Author(s):  
Natalie S. The ◽  
Margaret A. Honein ◽  
Alissa R. Caton ◽  
Cynthia A. Moore ◽  
Anna Maria Siega-Riz ◽  
...  
Keyword(s):  
Risk Factors ◽  
Biliary Atresia ◽  
Birth Defects ◽  
Prevention Study

Demographic and environmental risk factors for gastroschisis and omphalocele in the National Birth Defects Prevention Study

2009 ◽  
Vol 44 (8) ◽  
pp. 1546-1551 ◽  
Author(s):  
T. Mac Bird ◽  
James M. Robbins ◽  
Charlotte Druschel ◽  
Mario A. Cleves ◽  
Shengping Yang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Defects ◽  
Environmental Risk ◽  
Environmental Risk Factors ◽  
Prevention Study

scholarly journals Potential risk factors for Ebstein anomaly, National Birth Defects Prevention Study, 1997–2011

2019 ◽  
Vol 29 (06) ◽  
pp. 819-827 ◽  
Author(s):  
Karrie F. Downing ◽  
Tiffany Riehle-Colarusso ◽  
Suzanne M. Gilboa ◽  
Angela E. Lin ◽  
Matthew E. Oster ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Confidence Interval ◽  
Birth Defects ◽  
Odds Ratio ◽  
Paternal Age ◽  
Prevention Study ◽  
Ebstein Anomaly ◽  
Potential Risk Factors ◽  
History Of

AbstractBackground:Ebstein anomaly is a rare congenital heart defect (CHD) that, when severe, requires corrective surgery or other catheter-based intervention in the first year of life. Due to its rarity, risk factors for Ebstein anomaly remain largely unknown. Using national data, we examined 18 potential risk factors for Ebstein anomaly.Methods:Using 1997–2011 data from the National Birth Defects Prevention Study, a population-based case–control study, we calculated crude and adjusted odds ratios and 95% confidence intervals for paternal age, maternal socio-demographics, reproductive history, and modifiable risk factors, and infant characteristics reported by mothers of 135 Ebstein anomaly cases and 11,829 controls.Results:Mothers of Ebstein anomaly cases had 4.1 (95% confidence interval: 1.8, 9.5) times the odds of reporting a family history of CHD compared with mothers of controls. Ebstein anomaly was associated with maternal second-hand cigarette smoke exposure at home (odds ratio = 2.2 [95% confidence interval: 1.1, 4.4]), but not maternal cigarette smoking (odds ratio = 1.3 [95% confidence interval: 0.8, 2.1]). Odds were elevated, but the 95% confidence interval included 1.0, for maternal marijuana use (odds ratio = 1.8 [95% confidence interval: 0.9, 3.8]) and paternal age ≥40 years at delivery (odds ratio = 1.9 [95% confidence interval: 1.0, 3.5]).Conclusions:Maternal exposure to second-hand cigarette smoke at home and a family history of CHD were associated with elevated odds of Ebstein anomaly. Genetic analyses could clarify the potential heritability of Ebstein anomaly.

Severity of visual field defects in primary congenital glaucoma and their risk factors

2020 ◽  
Vol 258 (7) ◽  
pp. 1483-1491
Author(s):  
Ramanjit Sihota ◽  
Harathy Selvan ◽  
Ajay Sharma ◽  
Neeraj Gupta ◽  
Jyoti Shakrawal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Visual Field ◽  
Congenital Glaucoma ◽  
Visual Field Defects ◽  
Primary Congenital Glaucoma ◽  
Field Defects

scholarly journals Differences in risk factors for second and third degree hypospadias in the national birth defects prevention study

2014 ◽  
Vol 100 (9) ◽  
pp. 703-711 ◽  
Author(s):  
Sander Groen in 't Woud ◽  
Iris A.L.M. van Rooij ◽  
Marleen M.H.J. van Gelder ◽  
Richard S. Olney ◽  
Suzan L. Carmichael ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Defects ◽  
Prevention Study

Risk factors for non-syndromic holoprosencephaly in the National Birth Defects Prevention Study

2010 ◽  
Vol 154C (1) ◽  
pp. 62-72 ◽  
Author(s):  
Eric A. Miller ◽  
Sonja A. Rasmussen ◽  
Anna Maria Siega-Riz ◽  
Jaime L. Frías ◽  
Margaret A. Honein ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Defects ◽  
Prevention Study
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