Evidence for annular pancreas as an associated anomaly in the VATER/VACTERL association and investigation of the gene encoding pancreas specific transcription factor 1A as a candidate gene

2014 ◽  
Vol 164 (6) ◽  
pp. 1611-1613 ◽  
Author(s):  
Heiko Reutter ◽  
Nirmala Gurung ◽  
Michael Ludwig
Keyword(s):  
Transcription Factor ◽  
Candidate Gene ◽  
Annular Pancreas ◽  
Vacterl Association ◽  
Gene Encoding ◽  
Specific Transcription Factor

Cloning of the canine gene encoding transcription factor Pit-1 and its exclusion as candidate gene in a canine model of pituitary dwarfism

2000 ◽  
Vol 11 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Irma S. Lantinga-van Leeuwen ◽  
Jan A. Mol ◽  
Hans S. Kooistra ◽  
Ad Rijnberk ◽  
Matthew Breen ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Candidate Gene ◽  
Canine Model ◽  
Gene Encoding ◽  
Pituitary Dwarfism

scholarly journals AtMYB21, a gene encoding a flower-specific transcription factor, is regulated by COP1

2002 ◽  
Vol 30 (1) ◽  
pp. 23-32 ◽  
Author(s):  
Byongchul Shin ◽  
Goh Choi ◽  
Hankuil Yi ◽  
Seungchan Yang ◽  
Insook Cho ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Gene Encoding ◽  
Specific Transcription Factor

scholarly journals Novel spoIIE Mutation That Causes Uncompartmentalized σF Activation in Bacillus subtilis

2003 ◽  
Vol 185 (5) ◽  
pp. 1590-1598 ◽  
Author(s):  
David W. Hilbert ◽  
Patrick J. Piggot
Keyword(s):  
Transcription Factor ◽  
Bacillus Subtilis ◽  
Mother Cell ◽  
Critical Role ◽  
Asymmetric Division ◽  
Small Subset ◽  
Gene Encoding ◽  
Specific Transcription Factor ◽  
Fold Reduction ◽  
Optimal Efficiency

ABSTRACT During sporulation, Bacillus subtilis undergoes an asymmetric division that results in two cells with different fates, the larger mother cell and the smaller forespore. The protein phosphatase SpoIIE, which is required for activation of the forespore-specific transcription factor σF, is also required for optimal efficiency and timing of asymmetric division. We performed a genetic screen for spoIIE mutants that were impaired in sporulation but not σF activity and isolated a strain with the mutation spoIIEV697A. The mutant exhibited a 10- to 40-fold reduction in sporulation and a sixfold reduction in asymmetric division compared to the parent. Transcription of the σF-dependent spoIIQ promoter was increased more than 10-fold and was no longer confined to the forespore. The excessive σF activity persisted even when asymmetric division was prevented. Disruption of spoIIGB did not restore asymmetric division to the spoIIEV697A mutant, indicating that the deficiency is not a consequence of predivisional activation of the mother cell-specific transcription factor σE. Deletion of the gene encoding σF (spoIIAC) restored asymmetric division; however, a mutation that dramatically reduced the number of promoters responsive to σF, spoIIAC561 (spoIIACV233 M), failed to do so. This result suggests that the block is due to expression of one of the small subset of σF-dependent genes expressed in this background or to unregulated interaction of σF with some other factor. Our results indicate that regulation of SpoIIE plays a critical role in coupling asymmetric division to σF activation in order to ensure proper spatial and temporal expression of forespore-specific genes.

Characterization of the gene encoding human pituitary-specific transcription factor, Pit-1

Gene ◽  
1992 ◽  
Vol 122 (2) ◽  
pp. 387-388 ◽  
Author(s):  
Kohji Ohta ◽  
Yoshitaka Nobukuni ◽  
Hiroshi Mitsubuchi ◽  
Tohru Ohta ◽  
Takaya Tohma ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Gene Encoding ◽  
Human Pituitary ◽  
Specific Transcription Factor

Acetylation of Myeloid-Specific Transcription Factor C/EBPα

2012 ◽  
Vol 224 (03) ◽  
Author(s):  
I Kuznetsova ◽  
K Welte ◽  
J Skokowa
Keyword(s):  
Transcription Factor ◽  
Specific Transcription Factor ◽  
Factor C
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