A tortuous proximal urethra in urorectal septum malformation sequence?

2014 ◽  
Vol 164 (5) ◽  
pp. 1298-1303 ◽  
Author(s):  
Henry J. Lin ◽  
Hector Lugo ◽  
Thu Tran ◽  
Jason P. Tovar ◽  
Julia Corral ◽  
...  
Keyword(s):  
Proximal Urethra

Small cell carcinoma arising from the proximal urethra

2004 ◽  
Vol 11 (8) ◽  
pp. 674-677 ◽  
Author(s):  
UDO RUDLOFF ◽  
SAMUEL A. AMUKELE ◽  
ROBERT MOLDWIN ◽  
XIAOYING QIAO ◽  
NORA MORGENSTERN
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Proximal Urethra

scholarly journals Cellular basis of urothelial squamous metaplasia

2005 ◽  
Vol 171 (5) ◽  
pp. 835-844 ◽  
Author(s):  
Feng-Xia Liang ◽  
Maarten C. Bosland ◽  
Hongying Huang ◽  
Rok Romih ◽  
Solange Baptiste ◽  
...  
Keyword(s):  
Vitamin A ◽  
Vitamin A Deficiency ◽  
Squamous Metaplasia ◽  
Culture Conditions ◽  
Growth Potential ◽  
Basal Cells ◽  
Cellular Basis ◽  
Proximal Urethra

Although the epithelial lining of much of the mammalian urinary tract is known simply as the urothelium, this epithelium can be divided into at least three lineages of renal pelvis/ureter, bladder/trigone, and proximal urethra based on their embryonic origin, uroplakin content, keratin expression pattern, in vitro growth potential, and propensity to keratinize during vitamin A deficiency. Moreover, these cells remain phenotypically distinct even after they have been serially passaged under identical culture conditions, thus ruling out local mesenchymal influence as the sole cause of their in vivo differences. During vitamin A deficiency, mouse urothelium form multiple keratinized foci in proximal urethra probably originating from scattered K14-positive basal cells, and the keratinized epithelium expands horizontally to replace the surrounding normal urothelium. These data suggest that the urothelium consists of multiple cell lineages, that trigone urothelium is closely related to the urothelium covering the rest of the bladder, and that lineage heterogeneity coupled with cell migration/replacement form the cellular basis for urothelial squamous metaplasia.

scholarly journals Penile Fracture: Simultaneous Complete Urethral Rupture with Bilateral Corpora Cavernosa Rupture

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Ibrahim Alnadhari ◽  
Osama Abdelhaleem Abdeljaleel ◽  
Venkata Ramana Pai Sampige ◽  
Ausama Abdulmuhsin ◽  
Ahmad Shamsodini
Keyword(s):  
Blunt Trauma ◽  
Sexual Intercourse ◽  
Rare Case ◽  
Urethral Injury ◽  
Penile Fracture ◽  
Surgical Exploration ◽  
Corpora Cavernosa ◽  
Retrograde Urethrogram ◽  
Proximal Urethra ◽  
Urethral Rupture

Penile fracture is not uncommon blunt trauma to the penis. Here, we present a rare case of penile fracture during sexual intercourse. The patient presented with penile swelling, bleeding per urethra, and inability to pass urine. Retrograde urethrogram showed significant extravasation of contrast from anterior penile urethra and no contrast passing to proximal urethra. Surgical exploration showed complete urethral rupture and bilateral cavernosal rupture. This case represents the value of urethrogram to evaluate the urethral injury and the association of complete urethral injury with bilateral ventral cavernosal injury.

Clinical Import of Beta-Adrenergic Activity in the Proximal Urethra

1980 ◽  
Vol 124 (2) ◽  
pp. 254-255 ◽  
Author(s):  
M.S. Rao ◽  
B.C. Bapna ◽  
P.L. Sharma ◽  
K.S.N. Chary ◽  
S. Vaidyanathan
Keyword(s):  
Beta Adrenergic ◽  
Adrenergic Activity ◽  
Proximal Urethra

scholarly journals The Urothelium: Life in a Liquid Environment

2020 ◽  
Vol 100 (4) ◽  
pp. 1621-1705 ◽  
Author(s):  
Marianela G. Dalghi ◽  
Nicolas Montalbetti ◽  
Marcelo D. Carattino ◽  
Gerard Apodaca
Keyword(s):  
Current Knowledge ◽  
Nerve Fibers ◽  
Liquid Environment ◽  
Afferent Nerve Fibers ◽  
Proximal Urethra ◽  
Key Aspects ◽  
And Function ◽  
Solute Composition ◽  
Extended Discussion

The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra, forms a high-resistance but adaptable barrier that surveils its mechanochemical environment and communicates changes to underlying tissues including afferent nerve fibers and the smooth muscle. The goal of this review is to summarize new insights into urothelial biology and function that have occurred in the past decade. After familiarizing the reader with key aspects of urothelial histology, we describe new insights into urothelial development and regeneration. This is followed by an extended discussion of urothelial barrier function, including information about the roles of the glycocalyx, ion and water transport, tight junctions, and the cellular and tissue shape changes and other adaptations that accompany expansion and contraction of the lower urinary tract. We also explore evidence that the urothelium can alter the water and solute composition of urine during normal physiology and in response to overdistension. We complete the review by providing an overview of our current knowledge about the urothelial environment, discussing the sensor and transducer functions of the urothelium, exploring the role of circadian rhythms in urothelial gene expression, and describing novel research tools that are likely to further advance our understanding of urothelial biology.

Balloon dilation of a urethral stricture caused by a congenital obstructive proximal urethral membrane (COPUM) in a dog

2020 ◽  
Vol 8 (2) ◽  
pp. e001084
Author(s):  
Darren Kelly ◽  
Ingrid Isaac ◽  
Judith Cruzado-Perez ◽  
Florence Juvet
Keyword(s):  
Urethral Stricture ◽  
Balloon Dilation ◽  
Clinical Signs ◽  
Human Beings ◽  
Membranous Structure ◽  
First Report ◽  
Urethral Strictures ◽  
The Future ◽  
History Of ◽  
Proximal Urethra

Congenital urethral strictures are well recognised in human beings and have recently been described in two cats but have not been previously reported in dogs. A 10-month-old female English Bull Terrier presented with a life-long history of being unable to pass a normal stream of urine. Urethrocystoscopy confirmed the presence of a stricture lesion in the proximal urethra. This thin, membranous structure was effaced under endoscopic visualisation using a 10 mm diameter balloon-dilation catheter. Complete and sustained resolution of clinical signs occurred after a single dilation procedure. To the best of our knowledge, this is the first report of a congenital urethral stricture in a dog and the term congenital obstructive proximal urethral membrane may be useful for describing these lesions in the future.

scholarly journals Ultrasonographic Assessment with Three-Dimensional Mode of the Urethral Compression Effect following Sling Surgery with and without Mesh Surgery

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Kun-Ling Lin ◽  
Yung-Shun Juan ◽  
Shih-hsiang Chou ◽  
Cheng-Yu Long
Keyword(s):  
Pelvic Organ Prolapse ◽  
Three Dimensional ◽  
Pelvic Organ ◽  
Short Axis ◽  
Anatomical Changes ◽  
Mesh Surgery ◽  
Sling Surgery ◽  
Perineal Ultrasonography ◽  
Proximal Urethra ◽  
Ultrasonographic Assessment

Background. The aim of this study was to assess anatomical changes in the urethra at rest and during straining following sling surgery with and without transvaginal mesh surgery (TVM) in women with stress urinary incontinence (SUI) with or without pelvic organ prolapse (POP) using three-dimensional ultrasonography. Methods. 76 women with SUI with or without pelvic organ prolapse after sling surgery. They underwent sling surgery alone (S group, n=36) or concomitant TVM (M group, n=40). All patients underwent urinalysis, pelvic examinations, urodynamic study, 3D perineal ultrasonography, and personal interviews before and 1 year after surgery. The urethral area was calculated from the axial plane of perineal ultrasonography by multiplying π by the long and short axes of the urethral lumen. Results. The axial area of the middle and distal urethra during straining was significantly smaller than at rest in both groups (P<0.001). In addition, the length of the short axis of the proximal urethra was significantly shorter in those undergoing sling surgery alone during straining compared with those undergoing concomitant sling and mesh surgery (P<0.001). Conclusions. There was a greater impact on the proximal urethra in women who underwent sling surgery alone than those who underwent sling and TVM surgery together.

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