What does ?A gene for heart disease? mean? A focus group study of public understandings of genetic risk factors

2003 ◽  
Vol 119A (2) ◽  
pp. 156-161 ◽  
Author(s):  
Benjamin R. Bates ◽  
Alan Templeton ◽  
Paul J. Achter ◽  
Tina M. Harris ◽  
Celeste M. Condit
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Focus Group ◽  
Genetic Risk ◽  
Genetic Risk Factors ◽  
Focus Group Study

Familial aggregation of coronary heart disease and its relation to known genetic risk factors

1982 ◽  
Vol 50 (5) ◽  
pp. 945-953 ◽  
Author(s):  
Leo P. ten Kate ◽  
Helge Boman ◽  
Stephen P. Daiger ◽  
Arno G. Motulsky
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Genetic Risk ◽  
Familial Aggregation ◽  
Genetic Risk Factors

Genetic Risk Factors for Coronary Heart Disease in the Japanese Population

1991 ◽  
pp. 110-126 ◽  
Author(s):  
H. Hamaguchi ◽  
S. Kikuchi ◽  
H. Yanagi ◽  
T. Matsunaga ◽  
Y. Yamanouchi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Genetic Risk ◽  
Japanese Population ◽  
Genetic Risk Factors

Genetic risk factors in coronary heart disease (CHD) and restenosis

2000 ◽  
Vol 151 (1) ◽  
pp. 108
Author(s):  
L. Previato ◽  
F. Sandrelli ◽  
S. Stefanato ◽  
A. Codemo ◽  
R. Razzolini ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Genetic Risk ◽  
Genetic Risk Factors

scholarly journals Influence of Genetic Risk Factors on Coronary Heart Disease Occurrence in Afro-Caribbeans

2016 ◽  
Vol 32 (8) ◽  
pp. 978-985 ◽  
Author(s):  
Laurent Larifla ◽  
Katherine E. Beaney ◽  
Lydia Foucan ◽  
Jacqueline Bangou ◽  
Carl T. Michel ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Genetic Risk ◽  
Genetic Risk Factors ◽  
Disease Occurrence

scholarly journals A multicenter case-control study on non-genetic risk factors in infants with congenital heart disease

2019 ◽  
Author(s):  
Wei Ye ◽  
Xiao-Long Deng ◽  
Sheng Huang ◽  
Tong-Qiang Zhang ◽  
Qi-Zhu Tang
Keyword(s):  
Risk Factors ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Genetic Risk ◽  
Congenital Heart ◽  
Perinatal Period ◽  
Genetic Risk Factors ◽  
General Situation ◽  
Control Group ◽  
Case Group

Abstract Background: The incidence of congenital heart disease (CHD) is growing at a rapid speed worldwide, which due to changes of both environmental and lifestyle exposures. This study aimed to explore how the non-genetic risk factors of maternal and perinatal conditions influenced onset of CHD in infants.Methods: Infants with congenital heart disease diagnosed by echocardiography from May 2012 to December 2013 were recruited as positive cases, while healthy individuals without congenital heart disease recruited at the same period were regarded as controls. The general situation of parents and the exposure to environmental factors during perinatal period in the case group and the control group were investigated by questionnaires.Results: A total of424 questionnaires of infants with congenital heart disease and 362 healthy controls were finally collected. We analyzed the risk factors during perinatal period of their mothers showed that their mothers took drugs in early pregnancy (odds ratio [OR]=4.41, 95 % confidence interval [CI]:2.41-6.73), viral infection (OR = 2.97, 95% CI: 1.62-5.73), house decoration (OR = 1.82, 95% CI: 1.43-3.75), hair dyeing and scalding (OR = 2.24, 95% CI:1.46-4.05), parents' exposures to work environment pollution (OR = 2.77, 95% CI: 2.03-5.38) were independent risk factors for cardiovascular malformations. With the increase of exposure factors, the risk of congenital heart disease increased significantly. When pregnant women were exposed to three or more risk factors at the same time, the risk of infants with congenital heart disease in was 17.24 times higher than that of single-factor exposure.Conclusions: Together, the incidence of CHD in infants is correlated with the exposure to perinatal risk factors.

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