Organic dust exposure from compost handling: Response of an animal model

1993 ◽  
Vol 24 (4) ◽  
pp. 375-385 ◽  
Author(s):  
D. G. Frazer ◽  
W. G. Jones ◽  
E. L. Petsonk ◽  
G. J. Kullman ◽  
M. W. Barger ◽  
...  
Keyword(s):  
Animal Model ◽  
Dust Exposure ◽  
Organic Dust

Respiratory Symptoms and Farming Practices in Farmers Associated With an Acute Febrile Illness After Organic Dust Exposure

CHEST Journal ◽  
1999 ◽  
Vol 116 (5) ◽  
pp. 1452-1458 ◽  
Author(s):  
Susanna Von Essen ◽  
Jon Fryzek ◽  
Bogdan Nowakowski ◽  
Mary Wampler
Keyword(s):  
Respiratory Symptoms ◽  
Febrile Illness ◽  
Dust Exposure ◽  
Acute Febrile Illness ◽  
Organic Dust ◽  
Farming Practices

Airway Diseases Due to Organic Dust Exposure

2021 ◽  
pp. 293-302
Author(s):  
Jill A. Poole ◽  
Santiago Quirce ◽  
Andrea Siracusa ◽  
Maria Jesús Cruz Carmona ◽  
Amber N. Johnson ◽  
...  
Keyword(s):  
Dust Exposure ◽  
Organic Dust ◽  
Airway Diseases

Acute Airway Diseases Due to Organic Dust Exposure

2006 ◽  
pp. 641-682
Author(s):  
l Bernstein ◽  
Susanna Von Essen ◽  
Jaspal Singh ◽  
David Schwartz
Keyword(s):  
Dust Exposure ◽  
Organic Dust ◽  
Airway Diseases

Airway diseases due to organic dust exposure

2013 ◽  
pp. 357-374
Author(s):  
Moira Chan-Yeung ◽  
I. Leonard Bernstein ◽  
Susanna Von Essen ◽  
Jill A. Poole
Keyword(s):  
Dust Exposure ◽  
Organic Dust ◽  
Airway Diseases

scholarly journals O3A.6 Recent organic dust exposure and prognosis of asthma and chronic obstructive lung disease (COPD). A nationwide register based follow-up study

2019 ◽  
Vol 76 (Suppl 1) ◽  
pp. A23.1-A23
Author(s):  
Anne Vested ◽  
Ioannis Basinas ◽  
Alex Burdorf ◽  
Grethe Elholm ◽  
Dick Heederik ◽  
...  
Keyword(s):  
Hospital Readmission ◽  
Air Pollutants ◽  
Labour Force ◽  
Survival Function ◽  
Labour Force Participation ◽  
Dust Exposure ◽  
Organic Dust ◽  
Wood Industry ◽  
Recent Exposure ◽  
Overall Mortality

BackgroundAir pollutants at work can contribute to onset of asthma and COPD. How occupational air pollutants affect the prognosis of asthma or COPD among exposed workers is not well established.ObjectiveWe aimed, among individuals with a hospital diagnosis of asthma or COPD, to study the association between recent exposure to organic dust, and hospital readmission and overall mortality.MethodsThe study population comprised individuals ever employed in farming or wood industry with asthma (n=4002) or COPD (n=2429) identified in the Danish national patient register of individuals born 1933–1977. Subjects were included the year immediately following their first asthma or COPD hospital contact (earliest in 1998) and followed until first asthma or COPD readmission, death, or December 31 st 2007. Exposure data was obtained through register-based industry codes from 1997–2007 combined with time-dependent farming and wood industry-specific exposure matrices. We used logistic regression analysis with discrete survival function adjusted for age, calendar year, sex, mineral dust exposure, socioeconomic status, and labour-force participation.ResultsAmong individuals with asthma, the risk of hospital readmission was slightly increased among the exposed vs. the non-exposed, RRadj 1.17 (0.91–1.50), but with no exposure trend. A non-significant decrease in mortality was seen for organic dust exposure and mortality for those individuals, RRadj 0.71 (0.24–2.06).The risk of a COPD readmission among individuals with COPD was decreased among exposed vs. non-exposed individuals, RRadj 0.67 (0.46–0.98), but with no exposure trend. Mortality was non-significantly increased for exposed vs. non-exposed individuals with COPD, RRadj 1.59 (0.82–3.08).ConclusionWe did not observe significant associations between recent exposure to organic dust and readmission for COPD/asthma or overall mortality except for a decreased risk for COPD readmission. Selection effects are presumably playing a role. We did adjust for socioeconomic position and labour-force participation but not for smoking which is a limitation.

scholarly journals Equine Recurrent Airway Obstruction

2014 ◽  
Vol 37 (2) ◽  
pp. 115-120 ◽  
Author(s):  
Artur Niedźwiedź
Keyword(s):  
Pulmonary Function ◽  
Airway Obstruction ◽  
Environmental Changes ◽  
Clinical Signs ◽  
Dust Exposure ◽  
Common Disease ◽  
Recurrent Airway Obstruction ◽  
Organic Dust ◽  
Mucus Production ◽  
Neutrophilic Inflammation

AbstractEquine Recurrent Airway Obstruction (RAO), also known as heaves or broken wind, is one of the most common disease in middle-aged horses. Inflammation of the airway is inducted by organic dust exposure. This disease is characterized by neutrophilic inflammation, bronchospasm, excessive mucus production and pathologic changes in the bronchiolar walls. Clinical signs are resolved in 3-4 weeks after environmental changes. Horses suffering from RAO are susceptible to allergens throughout their lives, therefore they should be properly managed. In therapy the most importanthing is to eliminate dust exposure, administration of corticosteroids and use bronchodilators to improve pulmonary function.

scholarly journals Pulmonary reactions to organic dust exposures: development of an animal model.

1996 ◽  
Vol 104 (suppl 1) ◽  
pp. 41-53 ◽  
Author(s):  
V Castranova ◽  
V A Robinson ◽  
D G Frazer
Keyword(s):  
Animal Model ◽  
Organic Dust

Organic dust exposure and work-related effects among recycling workers

2003 ◽  
Vol 43 (6) ◽  
pp. 584-591 ◽  
Author(s):  
Toni Gladding ◽  
J�rgen Thorn ◽  
David Stott
Keyword(s):  
Dust Exposure ◽  
Organic Dust ◽  
Work Related

Questionnaire evaluating organic dust exposure

1990 ◽  
Vol 17 (1) ◽  
pp. 121-126 ◽  
Author(s):  
Ragnar Rylander ◽  
Yvonne Peterson ◽  
Kelley J. Donham
Keyword(s):  
Dust Exposure ◽  
Organic Dust

Flour dust – aspiration fraction Documentation of proposed values of occupational exposure limits (OELs

2017 ◽  
Vol 33 (3(93)) ◽  
pp. 91-120
Author(s):  
Agata Stobnicka ◽  
Rafał Górny
Keyword(s):  
Occupational Exposure ◽  
Animal Feed ◽  
Crystalline Silica ◽  
The Body ◽  
Dust Exposure ◽  
Cereal Grains ◽  
Animal Origin ◽  
Organic Dust ◽  
Respirable Fraction ◽  
Flour Dust

The term "flour dust" refers to particles derived from finely ground cereal grains and "non-cereal" grains. Flour flour usually also contains ingredients that play an important role in improving dough quality, such as enzymes, additives such as baker's yeast, flavors, spices and chemical ingredients such as preservatives. Flour is one of the basic raw materials used in the food industry and in the production of animal feed. Taking into account the nature of the production activities in mentioned industries, the highest occupational exposure to flour dust is usually observed in bakeries and grain mills. Significant exposure to flour dust is also found in factories of pasta, pizzeria and pastry, restaurant kitchens, malt factories, animal feed factories and agriculture. The main route of exposure to flour dust in occupational conditions is respiratory and skin. The main effect of repeated or long-lasting human exposure to flour dust is irritation and allergy. Epidemiological reports have shown that asthma, conjunctivitis, rhinitis and skin reactions are the main adverse health effects of flour dust exposure. Currently in Poland for flour dust the maximum admissible value (MAC, NDS) is the same as for organic dust (plant and animal origin). The MAC values are: for inhalable fraction 2 mg/m3 and for respirable fraction 1 mg/m3 when dust contains 10% or more crystalline silica and when dust contains less than 10% of crystalline silica, 4 mg/m3 for inhalable fraction and 2 mg/m3 for respirable fraction. The need to prepare documentation for flour dust resulted from the fact that existing documentation and MAC values mainly concern the effects of farmers' exposure to organic dust of plant and animal origin. It did not refer to flour dust for which the sensitization effect is critical. The basic mechanism of action of the flour dust on the body is the reaction of hypersensitivity with stimulation antibodies type E (IgE) developing shortly after exposure to the antigen. The value of hygienic norms for flour dust in Poland has not been established, yet. There is no data regarding animal experiments and in vitro studies with flour dust. On the basis of epidemiological studies, the risk of nasal symptoms has been found to increase with dust concentrations of 1 mg/m3 and the risk of asthma at concentrations above 3 mg/m3. The SCOEL assumes that exposure to the inhalable fraction of flour at a concentration of ≤ 1 mg/m3 protects most exposed workers from nasal mucositis and that the predicted symptoms, if present, are mild. However, the concentration of flour dust <1 mg/m3 may cause symptoms in already sensitized workers. The results of the study show that the full protection against allergens present in the flour dust in the air at low concentrations is difficult to achieve. At the same time, ACGIH's recommended TLV value for the inhalable flour dust fraction at 0.5 mg/m3 (8-h TWA). The "dose-response" results suggest that the symptoms of exposure to flour, especially from the lower respiratory tract, asthma, as well as the risk of sensitization, are rare in the inhalable fraction concentration in the range 0.5  1 mg/m3. Considering the above, the Interdepartmental Commission for MAC and MAI at the 84th meeting of 4.11.2016 adopted the TLV value for the inhalable fraction of flour dust at the level of 2 mg/m3, that is, at the level of the current MAC value for inhalable fraction of dust containing > 10% of the crystalline silica. No grounds for determining the short-term limit MAC(STEL) and the limit value in biological material. The standard is marked with "A" (sensitizing substance).

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