scholarly journals Non‐malignant respiratory disease among workers in the rubber manufacturing industry: A systematic review and meta‐analysis

2019 ◽  
Vol 62 (5) ◽  
pp. 367-384
Author(s):  
Nirmala Thapa ◽  
Suzanne E. Tomasi ◽  
Jean M. Cox‐Ganser ◽  
Randall J. Nett
Keyword(s):  
Systematic Review ◽  
Respiratory Disease ◽  
Manufacturing Industry ◽  
Meta Analysis

scholarly journals Effects of exercise training on physical and psychosocial health in children with chronic respiratory disease: a systematic review and meta-analysis

2018 ◽  
Vol 4 (1) ◽  
pp. e000409 ◽  
Author(s):  
Barbara Joschtel ◽  
Sjaan R Gomersall ◽  
Sean Tweedy ◽  
Helen Petsky ◽  
Anne B Chang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Lung Function ◽  
Exercise Training ◽  
Respiratory Disease ◽  
Effect Size ◽  
Meta Analysis ◽  
Chronic Respiratory Disease ◽  
Cardiovascular Fitness ◽  
Standard Mean Difference ◽  
Children With Asthma

IntroductionChronic disease in children is increasing, including the prevalence of chronic respiratory diseases such as asthma, cystic fibrosis (CF), bronchiectasis and bronchopulmonary dysplasia (BPD). The aim of this systematic review and meta-analysis was to evaluate the effects of exercise training on health outcomes in children with chronic respiratory disease.MethodFive databases were searched for randomised controlled trials investigating the effects of exercise training on children with chronic respiratory disease. Following the PRISMA guidelines, eligible studies were identified and data were extracted. A meta-analysis was conducted for the outcomes cardiovascular fitness, lung function and quality of life (QoL).ResultsThe initial search returned 3688 papers. Twenty-seven (17 in children with asthma, 10 in children with CF) were included in the systematic review and 24 of these were included in the meta-analysis. No studies were identified in children with bronchiectasis or BPD. Included papers had a total of 1009 participants aged 8–20 years. In addition to cardiovascular fitness, lung function and QoL, studies also assessed pulmonary function, respiratory muscle strength, muscular strength and inflammation. Meta-analysis showed a large significant effect size in favour of exercise for cardiovascular fitness (peak VO2) (standard mean difference (SMD)=1.16, 95%  CI 0.61 to 1.70) and QoL (SMD=1.27, 95% CI 0.72 to 1.82) as well as a small, non-significant effect size for lung function (FEV1) (SMD=0.02, 95% CI -0.38 to 0.42).ConclusionExercise training significantly improves cardiovascular fitness and QoL in children with asthma and CF. Further research is needed, particularly in children with bronchiectasis and BPD.

scholarly journals A systematic review and network meta-analysis of injectable antibiotic options for the control of bovine respiratory disease in the first 45 days post arrival at the feedlot

2019 ◽  
Vol 20 (2) ◽  
pp. 163-181
Author(s):  
A. M. O'Connor ◽  
D. Hu ◽  
S. C. Totton ◽  
N. Scott ◽  
C. B. Winder ◽  
...  
Keyword(s):  
Systematic Review ◽  
Beef Cattle ◽  
Respiratory Disease ◽  
Citation Index ◽  
Meta Analysis ◽  
Bovine Respiratory Disease ◽  
The United States ◽  
Feedlot Cattle ◽  
Freedom Of Information ◽  
Biological Index

AbstractWe conducted a systematic review and network meta-analysis to determine the comparative efficacy of antibiotics used to control bovine respiratory disease (BRD) in beef cattle on feedlots. The information sources for the review were: MEDLINE®, MEDLINE In-Process and MEDLINE® Daily, AGRICOLA, Epub Ahead of Print, Cambridge Agricultural and Biological Index, Science Citation Index, Conference Proceedings Citation Index – Science, the Proceedings of the American Association of Bovine Practitioners, World Buiatrics Conference, and the United States Food and Drug Administration Freedom of Information New Animal Drug Applications summaries. The eligible population was weaned beef cattle raised in intensive systems. The interventions of interest were injectable antibiotics used at the time the cattle arrived at the feedlot. The outcome of interest was the diagnosis of BRD within 45 days of arrival at the feedlot. The network meta-analysis included data from 46 studies and 167 study arms identified in the review. The results suggest that macrolides are the most effective antibiotics for the reduction of BRD incidence. Injectable oxytetracycline effectively controlled BRD compared with no antibiotics; however, it was less effective than macrolide treatment. Because oxytetracycline is already commonly used to prevent, control, and treat BRD in groups of feedlot cattle, the use of injectable oxytetracycline for BRD control might have advantages from an antibiotic stewardship perspective.

scholarly journals Non-communicable respiratory disease in Malawi: a systematic review and meta-analysis

2020 ◽  
Vol 32 (2) ◽  
pp. 64-73
Author(s):  
Rebecca Nightingale
Keyword(s):  
Systematic Review ◽  
Respiratory Disease ◽  
Meta Analysis ◽  
Airflow Obstruction ◽  
Secondary Data ◽  
Chronic Respiratory Disease ◽  
African Countries ◽  
History Of ◽  
Sub Saharan ◽  
The Life Course

BackgroundNon-communicable respiratory diseases are important contributors to morbidity and mortality in sub-Saharan African countries such as Malawi. AimTo conduct a systematic review of the available literature relating to chronic respiratory disease in Malawi. MethodsWe conducted a systematic protocol-driven literature search of key scientific databases including Scopus and Medline. Papers were independently assessed for eligibility by two authors and included if they reported objective measures (including self-reported standard symptoms) of chronic respiratory disease and were conducted in Malawi. A meta-analysis of available estimates was then conducted. We re-analysed data from three of these studies in a secondary data analysis to allow for between-study comparisons. ResultsOur search identified 393 papers of which 17 (5 involving children and 12 involving adults) met the inclusion criteria. Wheeze was the symptom most frequently reported in children in the community (12.1%), hospital (11.2%) and HIV clinic (8.1%) settings. Cough was the symptom most frequently reported by adults in the community (3–18%). Spirometric abnormalities varied substantially between studies. For example, in adults, airflow obstruction varied between 2.3% and 20% and low forced vital capacity (FVC) varied between 2.7% and 52.8%. ConclusionWe identified a high burden of chronic respiratory symptoms and abnormal spirometry (particularly low FVC) within paediatric and adult populations in Malawi. The estimates for country-wide burden related to this disease were limited by the heterogeneity of the methods used to assess symptoms and spirometry. There is an urgent need to develop a better understanding of the determinants and natural history of non-communicable respiratory disease across the life-course in Malawi.

scholarly journals Efficacy of bacterial vaccines to prevent respiratory disease in swine: a systematic review and network meta-analysis

2019 ◽  
Vol 20 (2) ◽  
pp. 274-290 ◽  
Author(s):  
Jan M. Sargeant ◽  
Bhumika Deb ◽  
Michele D. Bergevin ◽  
Katheryn Churchill ◽  
Kaitlyn Dawkins ◽  
...  
Keyword(s):  
Systematic Review ◽  
Respiratory Disease ◽  
Pasteurella Multocida ◽  
Meta Analysis ◽  
Grey Literature ◽  
Antibiotic Use ◽  
Bordetella Bronchiseptica ◽  
Comparative Efficacy ◽  
Lung Lesions ◽  
Actinobacillus Suis

AbstractA systematic review and network meta-analysis (MA) was conducted to address the question, ‘What is the efficacy of bacterial vaccines to prevent respiratory disease in swine?’ Four electronic databases and the grey literature were searched to identify clinical trials in healthy swine where at least one intervention arm was a commercially available vaccine for one or more bacterial pathogens associated with respiratory disease in swine, including Mycoplasma hyopneumoniae, Actinobacillus pleuropneumonia, Actinobacillus suis, Bordetella bronchiseptica, Pasteurella multocida, Stretococcus suis, Haemophils parasuis, and Mycoplasma hyorhinis. To be eligible, trials had to measure at least one of the following outcomes: incidence of clinical morbidity, mortality, lung lesions, or total antibiotic use. There were 179 eligible trials identified in 146 publications. Network MA was undertaken for morbidity, mortality, and the presence or absence of non-specific lung lesions. However, there was not a sufficient body of research evaluating the same interventions and outcomes to allow a meaningful synthesis of the comparative efficacy of the vaccines. To build this body of research, additional rigor in trial design and analysis, and detailed reporting of trial methods and results are warranted.

scholarly journals Glucocorticoid-induced hyperglycaemia in respiratory disease: a systematic review and meta-analysis

2016 ◽  
Vol 18 (12) ◽  
pp. 1274-1278 ◽  
Author(s):  
S. Breakey ◽  
S. J. Sharp ◽  
A. I. Adler ◽  
B. G. Challis
Keyword(s):  
Systematic Review ◽  
Respiratory Disease ◽  
Meta Analysis

scholarly journals Comparison of Microbiota in the Upper Versus Lower Respiratory Tract in Children During Health and Respiratory Disease: a Protocol for a Systematic Review

2020 ◽  
Author(s):  
Richa Rao ◽  
Joseph L. Mathew
Keyword(s):  
Systematic Review ◽  
Respiratory Disease ◽  
Meta Analysis ◽  
Research Question ◽  
Cochrane Library ◽  
Reference List ◽  
Healthy Children ◽  
Microbial Composition ◽  
Upper Airways ◽  
Asymptomatic Children

Abstract Background: Several species of organisms reside in the upper airways of healthy infants and children. In most cases they do no harm to the host despite being potentially pathogenic. In contrast, the lung in healthy people was considered to be a sterile environment, but sophisticated techniques have recently demonstrated colonization by a complex population of microorganisms in healthy adults. It is unclear if a similar situation happens in healthy children. In children with respiratory disease, several micro-organisms can be recovered from the upper as well as lower respiratory tracts. However, the correlation between organisms recovered from the two sites is unclear. This systematic review is designed to explore the microbial composition of the respiratory system in apparently healthy asymptomatic children, comparing the organisms identified in the upper airways versus the lungs. We also intend to compare the site-specific prevalence and pattern of organisms in healthy children versus those with various respiratory diseases. We will also compare the organism identified in the upper airway versus the lungs in children with respiratory disease.Methods: We will search the following electronic databases: Medline, Embase and the Cochrane Library. Reference list of relevant studies will be examined for links to potential related articles. Two reviewers will independently determine study eligibility. The methodological quality of the observational included studies will be scored using the Newcastle Ottawa Scale tool for assessing risk of bias. We will extract data from included studies and perform meta-analysis where feasible.Results: The search strategy will be refined and the literature search will take place independently by two authors. Final stage will include analyses and writing.Discussion: Through the publication of this protocol, readers will be able to assess the research question and methods presented in this protocol. Upon publication of the review, readers will be able to assess whether the review was conducted according to pre-defined plan. Researchers will be aware that the review is underway, thereby avoid duplication, and be able to use it as a basis for planning similar reviews.PROSPERO registration number: CRD42020202115

Sign in / Sign up

Export Citation Format

Share Document