Fetal brain ultrasound measures and maternal nutrition: A feasibility study in Ecuador

2020 ◽  
Author(s):  
Carrie A. Sibbald ◽  
Jennifer L. Nicholas ◽  
Melissa Chapnick ◽  
Naima Ross ◽  
Patricia L. Gandor ◽  
...  
Keyword(s):  
Feasibility Study ◽  
Maternal Nutrition ◽  
Fetal Brain ◽  
Brain Ultrasound

Analysis of maturation features in fetal brain ultrasound via Artificial Intelligence for the estimation of gestational age

2021 ◽  
pp. 100462
Author(s):  
Xavier P. Burgos-Artizzu ◽  
David Coronado-Gutiérrez ◽  
Brenda Valenzuela-Alcaraz ◽  
Kilian Vellvé ◽  
Elisenda Eixarch ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Gestational Age ◽  
Fetal Brain ◽  
Brain Ultrasound

Impact of fetal brain ultrasound tutor smartphone application on normal anatomy learning

2019 ◽  
Vol 39 (4) ◽  
pp. 303-307
Author(s):  
Nicola Volpe ◽  
Andrea Dall'Asta ◽  
Giovanni Battista Luca Schera ◽  
Elvira Di Pasquo ◽  
Tiziana Frusca ◽  
...  
Keyword(s):  
Fetal Brain ◽  
Smartphone Application ◽  
Normal Anatomy ◽  
Brain Ultrasound

Does normal fetal brain ultrasound predict normal neurodevelopmental outcome in congenital cytomegalovirus infection?

2011 ◽  
Vol 31 (4) ◽  
pp. 360-366 ◽  
Author(s):  
Natalie Farkas ◽  
Chen Hoffmann ◽  
Liat Ben-Sira ◽  
Dorit Lev ◽  
Avraham Schweiger ◽  
...  
Keyword(s):  
Cytomegalovirus Infection ◽  
Neurodevelopmental Outcome ◽  
Fetal Brain ◽  
Congenital Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus ◽  
Brain Ultrasound

scholarly journals Fully-automated alignment of 3D fetal brain ultrasound to a canonical reference space using multi-task learning

2018 ◽  
Vol 46 ◽  
pp. 1-14 ◽  
Author(s):  
Ana I.L. Namburete ◽  
Weidi Xie ◽  
Mohammad Yaqub ◽  
Andrew Zisserman ◽  
J. Alison Noble
Keyword(s):  
Fetal Brain ◽  
Task Learning ◽  
Reference Space ◽  
Brain Ultrasound ◽  
Automated Alignment

scholarly journals The effect of maternal undernutrition on ovine fetal growth

2002 ◽  
Vol 173 (1) ◽  
pp. 131-141 ◽  
Author(s):  
JC Osgerby ◽  
DC Wathes ◽  
D Howard ◽  
TS Gadd
Keyword(s):  
Fetal Growth ◽  
Bone Growth ◽  
Maternal Nutrition ◽  
Fetal Brain ◽  
Late Gestation ◽  
Adult Health ◽  
Semitendinosus Muscle ◽  
Fetal Plasma ◽  
Maternal Undernutrition ◽  
Igf I

Modifications in maternal nutrition during pregnancy can significantly disrupt fetal growth and subsequent post-natal health and survival. This study investigated the effects of undernutrition on fetal growth and the potential mechanisms involved. Tissue from pregnant ewes (n=27) was investigated on days 45, 90 and 135 of gestation (term = approximately 150 days). The thoracic girth (P<0.05) was greater in fetuses from nutrient restricted ewes on day 45 and there was also a trend towards an increased gut weight (P<0.08). By day 90, the fetal brain and thymus weight were lighter in underfed than in well-fed animals whilst the weight of the fetal ovaries was heavier (P<0.05). On day 135 the fetal heart, pancreas, thymus, gut and kidney weights were lighter in undernourished ewes (P<0.05). When expressed as a percentage of fetal body weight, significance was retained in the heart, pancreas and thymus (P<0.05). Bone growth was also affected. At day 90 the fetal femur and metatarsal were longer in underfed mothers (P<0.05). In contrast, the fetal humerus and scapula were shorter in underfed than in well-fed animals on day 135 (P<0.05) when the weight of the semitendinosus muscle (P<0.05) was also reduced. The fall in fetal glucose (P<0.1), insulin (P<0.01) and IGF-I (P<0.01) levels in underfed ewes on day 135 may have compromised fetal growth. Fetal plasma IGF binding protein-2 also increased between days 90 and 135 in underfed ewes (P<0.03), whilst levels were unaltered in well-fed animals. Although maternal and fetal plasma IGF-I levels increased with gestation (P<0.01) and the placentome morphology altered in all ewes (P<0.05), the fall in placental mass (P<0.05), amniotic and allantoic glucose concentrations (P<0.05) and maternal plasma glucose and insulin levels (P<0.05) in underfed ewes in late gestation may have compromised fetal substrate delivery. These perturbations in fetal development may have significant implications on adult health and carcass conformation, raising important health and economic issues in medical and agricultural sectors.

scholarly journals Maternal Protein Restriction in Rats Alters the Expression of Genes Involved in Mitochondrial Metabolism and Epitranscriptomics in Fetal Hypothalamus

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1464
Author(s):  
Morgane Frapin ◽  
Simon Guignard ◽  
Dimitri Meistermann ◽  
Isabelle Grit ◽  
Valentine S. Moullé ◽  
...  
Keyword(s):  
Maternal Nutrition ◽  
Rna Binding ◽  
Rna Binding Proteins ◽  
Fetal Brain ◽  
Protein Restriction ◽  
Metabolic Adaptation ◽  
Respiratory Chain Complexes ◽  
Maternal Protein Restriction ◽  
Genes Encoding

Fetal brain development is closely dependent on maternal nutrition and metabolic status. Maternal protein restriction (PR) is known to be associated with alterations in the structure and function of the hypothalamus, leading to impaired control of energy homeostasis and food intake. The objective of this study was to identify the cellular and molecular systems underlying these effects during fetal development. We combined a global transcriptomic analysis on the fetal hypothalamus from a rat model of maternal PR with in vitro neurosphere culture and cellular analyses. Several genes encoding proteins from the mitochondrial respiratory chain complexes were overexpressed in the PR group and mitochondrial metabolic activity in the fetal hypothalamus was altered. The level of the N6-methyladenosine epitranscriptomic mark was reduced in the PR fetuses, and the expression of several genes involved in the writing/erasing/reading of this mark was indeed altered, as well as genes encoding several RNA-binding proteins. Additionally, we observed a higher number of neuronal-committed progenitors at embryonic day 17 (E17) in the PR fetuses. Together, these data strongly suggest a metabolic adaptation to the amino acid shortage, combined with the post-transcriptional control of protein expression, which might reflect alterations in the control of the timing of neuronal progenitor differentiation.

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