Stability of variables associated with the metabolic syndrome from adolescence to adulthood: The Aerobics Center Longitudinal Study

2004 ◽  
Vol 16 (6) ◽  
pp. 690-696 ◽  
Author(s):  
Joey C. Eisenmann ◽  
Gregory J. Welk ◽  
Eric E. Wickel ◽  
Steven N. Blair
2006 ◽  
Vol 106 (5) ◽  
pp. 673-679 ◽  
Author(s):  
Carrie E. Finley ◽  
Michael J. LaMonte ◽  
Carol I. Waslien ◽  
Carolyn E. Barlow ◽  
Steven N. Blair ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lars Lind ◽  
Johan Sundström ◽  
Johan Ärnlöv ◽  
Ulf Risérus ◽  
Erik Lampa

AbstractThe impact of most, but not all, cardiovascular risk factors decline by age. We investigated how the metabolic syndrome (MetS) was related to cardiovascular disease (CVD) during 40 years follow-up in the Uppsala Longitudinal Study of Adult Men (ULSAM, 2,123 men all aged 50 at baseline with reinvestigations at age 60, 70, 77 and 82). The strength of MetS as a risk factor of incident combined end-point of three outcomes (CVD) declined with ageing, as well as for myocardial infarction, ischemic stroke and heart failure when analysed separately. For CVD, the risk ratio declined from 2.77 (95% CI 1.90–4.05) at age 50 to 1.30 (95% CI 1.05–1.60) at age 82. In conclusion, the strength of MetS as a risk factor of incident CVD declined with age. Since MetS was significantly related to incident CVD also at old age, our findings suggest that the occurrence of MetS in the elderly should not be regarded as innocent. However, since our data were derived in an observational study, any impact of MetS in the elderly needs to be verified in a randomized clinical intervention trial.


2012 ◽  
Vol 21 (4) ◽  
pp. 326-332 ◽  
Author(s):  
Geoffrey C. Kabat ◽  
Mimi Y. Kim ◽  
Ulrike Peters ◽  
Marcia Stefanick ◽  
Lifang Hou ◽  
...  

2006 ◽  
Vol 187 (2) ◽  
pp. 385-392 ◽  
Author(s):  
Marianna Noale ◽  
Stefania Maggi ◽  
Chiara Marzari ◽  
Federica Limongi ◽  
Pietro Gallina ◽  
...  

2012 ◽  
Vol 38 (2) ◽  
pp. 135-141 ◽  
Author(s):  
M. Noale ◽  
S. Maggi ◽  
S. Zanoni ◽  
F. Limongi ◽  
S. Zambon ◽  
...  

2009 ◽  
Vol 18 (7) ◽  
pp. 2046-2053 ◽  
Author(s):  
Geoffrey C. Kabat ◽  
Mimi Kim ◽  
Rowan T. Chlebowski ◽  
Janu Khandekar ◽  
Marcia G. Ko ◽  
...  

2015 ◽  
Vol 12 (1) ◽  
pp. 68-73 ◽  
Author(s):  
Anna E. Greer ◽  
Xuemei Sui ◽  
Andréa L. Maslow ◽  
Beau Kjerulf Greer ◽  
Steven N. Blair

Background:To date, no longitudinal studies have examined the influence of sedentary behavior on metabolic syndrome development while accounting for cardiorespiratory fitness.Purpose and Methods:This prospective study examined the relationship between sedentary behavior and incident metabolic syndrome while considering the effects of physical activity and cardiorespiratory fitness on the association among 930 men enrolled in the Aerobics Center Longitudinal Study.Results:A total of 124 men developed metabolic syndrome during 8974 person-years of exposure. After adjusting for covariates, men with middle and high sedentary behavior had 65% and 76% higher risks of developing metabolic syndrome, respectively, than men with low sedentary behavior (linear trend P = .011). This association remained significant after additional adjustment for activity status and cardiorespiratory fitness. Cardiorespiratory fitness and physical activity were also inversely associated with metabolic syndrome, even after adjustment for sedentary behavior.Conclusions:The findings highlight the importance of reducing sedentary behavior, increasing physical activity, and improving cardiorespiratory fitness for preventing metabolic syndrome.


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