scholarly journals Hepatosplenic ?? T-cell lymphoma presenting with immune-mediated thrombocytopenia and hemolytic anemia (Evans' syndrome)

2002 ◽  
Vol 69 (4) ◽  
pp. 272-276 ◽  
Author(s):  
G. Motta ◽  
F. Vianello ◽  
C. Menin ◽  
A. De Nicolo ◽  
S. Agata ◽  
...  
2015 ◽  
Vol 9 ◽  
pp. CMO.S35120 ◽  
Author(s):  
Feryal A. Ibrahim ◽  
Vignesh Shanmugam ◽  
Aliaa Amer ◽  
Halima El-Omri ◽  
Ahmad Al-Sabbagh ◽  
...  

Hepatosplenic T-cell lymphoma (HSTCL) is a rare and aggressive extranodal T-cell lymphoma that comprises <5% of peripheral T-cell lymphomas. The majority of cases harbor the γδT-cell receptor (TCR), but recently, a few cases have been shown to express the αß TCR. Comparison of these two subtypes (αβ and γδ) shows similar clinicopathologic and cytogenetic features; however, due to the paucity of reported cases, it is not clear whether they are prognostically distinct entities. We report a case of αβ HSTCL with a rather unusual presentation of Coombs'-negative hemolytic anemia. Diagnosis proved challenging due to an unusual blastoid morphology with the absence of typical intrasinusoidal distribution of tumor cells in the bone marrow. This unique case adds to the growing list of this rare subtype of T-cell lymphomas, which warrant urgent attention due to the lack of effective treatment options and dismal prognosis.


2000 ◽  
Vol 24 (3) ◽  
pp. 459-463 ◽  
Author(s):  
Raymond Lai ◽  
Loree M. Larratt ◽  
Wai Etches ◽  
Shane T. Mortimer ◽  
Lawrence D. Jewell ◽  
...  

2016 ◽  
Vol 50 ◽  
pp. 109-117 ◽  
Author(s):  
Mariko Yabe ◽  
L. Jeffrey Medeiros ◽  
Guilin Tang ◽  
Sa A. Wang ◽  
Keyur P. Patel ◽  
...  

2009 ◽  
Vol 2 (6) ◽  
pp. 611-614 ◽  
Author(s):  
Jenny Vu Pozadzides ◽  
Barbara Pro

2011 ◽  
Vol 25 (5) ◽  
pp. 1181-1185 ◽  
Author(s):  
K.F. McGovern ◽  
K.M. Lascola ◽  
E. Davis ◽  
R.L. Fredrickson ◽  
R. Tan

Gut ◽  
2008 ◽  
Vol 57 (12) ◽  
pp. 1639-1641 ◽  
Author(s):  
M. Shale ◽  
E. Kanfer ◽  
R. Panaccione ◽  
S. Ghosh

2015 ◽  
Vol 8 (2) ◽  
pp. 78-84 ◽  
Author(s):  
Philippa Ashmore ◽  
Moosa Patel ◽  
Jenifer Vaughan ◽  
Tracey Wiggill ◽  
Pascale Willem ◽  
...  

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