Severe thrombocytopenia and microangiopathic hemolytic anemia in pregnancy: A guide for the consulting hematologist

2021 ◽  
Author(s):  
Juliana Perez Botero ◽  
Jessica A. Reese ◽  
James N. George ◽  
Jennifer J. McIntosh
Keyword(s):  
Hemolytic Anemia ◽  
Severe Thrombocytopenia ◽  
Microangiopathic Hemolytic Anemia ◽  
Anemia In Pregnancy ◽  
In Pregnancy

Microangiopathic hemolytic anemia in pregnancy

2017 ◽  
Vol 56 (3) ◽  
pp. 354-356 ◽  
Author(s):  
Mohammed Salhab ◽  
Andrew Hsu ◽  
Elizabeth Ryer ◽  
Juliet Appiah ◽  
Bradley Switzer
Keyword(s):  
Hemolytic Anemia ◽  
Microangiopathic Hemolytic Anemia ◽  
Anemia In Pregnancy ◽  
In Pregnancy

Microangiopathic hemolytic anemia and severe thrombocytopenia in Brucella infection

1995 ◽  
Vol 70 (1) ◽  
pp. 59-60 ◽  
Author(s):  
A. Di Mario ◽  
S. Sica ◽  
G. Zini ◽  
P. Salutari ◽  
G. Leone
Keyword(s):  
Hemolytic Anemia ◽  
Severe Thrombocytopenia ◽  
Microangiopathic Hemolytic Anemia ◽  
Brucella Infection

Hemolytic Anemia in Pregnancy: Fetomaternal Outcome

2010 ◽  
Vol 2 (3) ◽  
pp. 212-215
Author(s):  
Vivek Paul Vithayathil ◽  
Sebanti Goswami ◽  
Suchi Katiyal ◽  
Utpal Chaudhuri ◽  
Partha Sarathi Chakravorty
Keyword(s):  
Hemolytic Anemia ◽  
Anemia In Pregnancy ◽  
In Pregnancy

Hemolytic anemia in pregnancy

1953 ◽  
Vol 65 (6) ◽  
pp. 1338-1344 ◽  
Author(s):  
John W. O'Grady ◽  
H.L. Riva ◽  
John G. Ritzenthaler
Keyword(s):  
Hemolytic Anemia ◽  
Anemia In Pregnancy ◽  
In Pregnancy

Microangiopathic hemolytic anemia and severe thrombocytopenia inBrucella infection

1995 ◽  
Vol 70 (1) ◽  
pp. 59-60 ◽  
Author(s):  
A. Di Mario ◽  
S. Sica ◽  
G. Zini ◽  
P. Salutari ◽  
G. Leone
Keyword(s):  
Hemolytic Anemia ◽  
Severe Thrombocytopenia ◽  
Microangiopathic Hemolytic Anemia

Acquired hemolytic anemia in pregnancy treated with acth and cortisone

1953 ◽  
Vol 65 (2) ◽  
pp. 421-423 ◽  
Author(s):  
Abraham M. Frumin ◽  
Eleanor Mallay Smith ◽  
Ann Gray Taylor ◽  
Mary B. Dratman
Keyword(s):  
Hemolytic Anemia ◽  
Anemia In Pregnancy ◽  
In Pregnancy

Microangiopathic Hemolytic Anemia Due to Malignancy in Pregnancy

2016 ◽  
Vol 128 (6) ◽  
pp. 1437-1440
Author(s):  
Sarah K. Happe ◽  
Amanda C. Zofkie ◽  
David B. Nelson
Keyword(s):  
Hemolytic Anemia ◽  
Microangiopathic Hemolytic Anemia ◽  
In Pregnancy

Management of Cold Agglutinin–Immune Hemolytic Anemia in Pregnancy

2007 ◽  
Vol 110 (Supplement) ◽  
pp. 485-486 ◽  
Author(s):  
Simi Dhingra ◽  
J J. Wiener ◽  
Helen Jackson
Keyword(s):  
Hemolytic Anemia ◽  
Cold Agglutinin ◽  
Immune Hemolytic Anemia ◽  
Anemia In Pregnancy ◽  
In Pregnancy

scholarly journals Acute Kidney Damage in Pregnancy: Etiopathogenesis, Diagnostics and Basic Principles of Treatment

2020 ◽  
Vol 21 (2) ◽  
pp. 113-119
Author(s):  
Branislava Draskovic ◽  
Tomislav Nikolic ◽  
Sasa Jacovic ◽  
Dejan Petrovic
Keyword(s):  
Fatty Acids ◽  
Magnesium Sulfate ◽  
Hemolytic Anemia ◽  
Hellp Syndrome ◽  
Alternative Pathway ◽  
Developed Countries ◽  
Kidney Damage ◽  
Microangiopathic Hemolytic Anemia ◽  
Extracorporeal Liver Support ◽  
In Pregnancy

AbstractAcute kidney damage associated with pregnancy occurs in 1/20.000 pregnancies. In developing countries, the main cause of the development of acute kidney damage is septic abortion, and preeclampsia in the developed countries of the world. Preeclampsia is defined as newly developed hypertension, proteinuria and swelling in pregnant women after the 20th week of gestation. It occurs due to disorders in the development of placenta and systemic disorders of the function of the endothelium of the mother. It is treated with methyldopa, magnesium sulfate and timely delivery. Urgent delivery is indicated if the age of gestation is ≥ 34 weeks. HELLP syndrome is a difficult form of preeclampsia. Its main characteristics are decreased platelet count, microangiopathic hemolysis anemia, increased concentration of aminotransferase in the serum and acute kidney damage. Severe HELLP syndrome is treated with emergency delivery, antihypertensives, magnesium sulfate, and in some cases plasmapheresis and hemodialysis. Acute fatty liver in pregnancy occurs because of decreased activity of the LCHAD enzyme of the fetus. Due to the reduced beta oxidation of fatty acids in the hepatocytes of the fetus, long chain fatty acids that cause damage to the mother’s hepatocytes are released. Swansea criteria are used for diagnosis, and the difficult form of the disease is treated with plasmapheresis and extracorporeal liver support. Atypical HUS is due to a reduced protein activity that regulates the activity of the alternative pathway of the complement system. Its main features are thrombocytopenia, microangiopathic hemolytic anemia and acute kidney damage. It is treated with plasmapheresis, and in case of resistance with eculizumab. Thrombotic thrombocytopenic purpura is due to decreased activity of the ADAMTS13 enzyme. It is characterized by thrombocytopenia, microangiopathic hemolytic anemia, high temperature, nervous system disorders and acute kidney damage. It is treated with plasmapheresis, and severe form of disease with corticosteroids and azathioprine. Early detection and timely treatment of acute kidney damage provides a good outcome for the mother and fetus.

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