Low‐dose Thymoglobulin for prevention of chronic graft‐versus‐host disease in transplantation from an HLA ‐matched sibling donor

2021 ◽  
Author(s):  
Byung‐Sik Cho ◽  
Gi‐June Min ◽  
Sung‐Soo Park ◽  
Seok Yoon Yoon ◽  
Silvia Park ◽  
...  
Keyword(s):  
Graft Versus Host Disease ◽  
Low Dose ◽  
Host Disease ◽  
Graft Versus Host ◽  
Sibling Donor ◽  
Matched Sibling

CLINICAL MANIFESTATIONS OF GRAFT-VERSUS-HOST DISEASE IN HUMAN RECIPIENTS OF MARROW FROM HL-A-MATCHED SIBLING DONOR,S

1974 ◽  
Vol 18 (4) ◽  
pp. 295-304 ◽  
Author(s):  
H. GLUCKSBERG ◽  
R. STORB ◽  
A. FEFER ◽  
C. D. BUCKNER ◽  
P. E. NEIMAN ◽  
...  
Keyword(s):  
Graft Versus Host Disease ◽  
Clinical Manifestations ◽  
Host Disease ◽  
Graft Versus Host ◽  
Sibling Donor ◽  
Matched Sibling

scholarly journals Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants

2018 ◽  
Vol 2 (9) ◽  
pp. 1022-1031 ◽  
Author(s):  
Anita J. Kumar ◽  
Soyoung Kim ◽  
Michael T. Hemmer ◽  
Mukta Arora ◽  
Stephen R. Spellman ◽  
...  
Keyword(s):  
Graft Versus Host Disease ◽  
Unrelated Donor ◽  
Host Disease ◽  
Graft Versus Host ◽  
Sibling Donor ◽  
Female Sibling ◽  
Key Points

Key Points Compared with parous female sibling donors, male URDs confer more aGVHD in all patients and more cGVHD in females. There was no difference in survival, relapse, or transplant mortality between recipients of parous female sibling or male URD grafts.

scholarly journals Uva1 Phototherapy in the Management of Sclerodermatous Graft-Versus-Host Disease (Gvhd): a report of two cases / Uva1 fototerapija u lečenju sklerodermatoznog oblika hronične Gvhd: Prikaz dva slučaja

2009 ◽  
Vol 1 (4) ◽  
pp. 147-152 ◽  
Author(s):  
Hiva Fassihi ◽  
Kamran Iqbal ◽  
Trish Garibaldinos ◽  
Robert Sarkany ◽  
Julia Scarisbrick ◽  
...  
Keyword(s):  
Graft Versus Host Disease ◽  
Skin Diseases ◽  
Hematopoietic Stem ◽  
Host Disease ◽  
Allogeneic Hsct ◽  
Graft Versus Host ◽  
Uva1 Phototherapy ◽  
Matched Sibling

Abstract Chronic graft-versus-host disease (GVHD) is a frequent complication after allogeneic hematopoietic stem cell transplantation (HSCT). Approximately 10% of patients with GVHD develop sclerodermatous changes, which can cause significant morbidity and are often refractory to standard systemic immunosuppression. We present two cases of sclerodermatous GVHD. The first is a 39-year-old man, who had a matched sibling, undergoing allogeneic HSCT for severe aplastic anemia. The second patient is a 7-year-old boy, who had an allogeneic HSCT from his HLA-identical mother for acute myeloid leukemia (AML). Both patients presented with widespread sclerotic changes, resulting in joint contractures and significant functional difficulties. Studies have shown UVA1 phototherapy to be a promising and well tolerated treatment modality in patients with sclerotic skin diseases. Both of our patients were treated with UVA1, which resulted in a significant skin softening, improvement in joint mobility and quality of life. UVA1 appears to be an effective treatment for refractory sclerodermatous GVHD; however, long-term clinical studies in larger groups are needed to accurately evaluate its efficacy and safety.

scholarly journals Reduced Efficacy of Low-dose Topical Steroids in Dry Eye Disease Associated With Graft-versus-Host Disease

2018 ◽  
Vol 190 ◽  
pp. 17-23 ◽  
Author(s):  
Jia Yin ◽  
Ahmad Kheirkhah ◽  
Thomas Dohlman ◽  
Ujwala Saboo ◽  
Reza Dana
Keyword(s):  
Dry Eye ◽  
Graft Versus Host Disease ◽  
Low Dose ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Topical Steroids ◽  
Host Disease ◽  
Graft Versus Host
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