scholarly journals Methylene blue-induced Heinz body hemolytic anemia in a premature neonate

2018 ◽  
Vol 93 (5) ◽  
pp. 716-717 ◽  
Author(s):  
Lewis Vanhinsbergh ◽  
Sabita Uthaya ◽  
Barbara J. Bain
Keyword(s):  
Methylene Blue ◽  
Hemolytic Anemia ◽  
Premature Neonate ◽  
Heinz Body

Heinz body hemolytic anemia from the use of methylene blue in neonates

1980 ◽  
Vol 96 (2) ◽  
pp. 276-278 ◽  
Author(s):  
Ilan R. Kirsch ◽  
Harvey J. Cohen
Keyword(s):  
Methylene Blue ◽  
Hemolytic Anemia ◽  
Heinz Body

Heinz-body hemolytic anemia associated with ingestion of methylene blue in a river otter

2002 ◽  
Vol 220 (3) ◽  
pp. 363-366 ◽  
Author(s):  
Neelesh S. Narurkar ◽  
Jennifer S. Thomas ◽  
David N. Phalen
Keyword(s):  
Methylene Blue ◽  
Hemolytic Anemia ◽  
River Otter ◽  
Heinz Body

Letter: Heinz body hemolytic anemia

1976 ◽  
Vol 136 (9) ◽  
pp. 1067a-1067
Author(s):  
E. P. Gabor
Keyword(s):  
Hemolytic Anemia ◽  
Heinz Body

Heinz-Body Anaemia in the Newborn

PEDIATRICS ◽  
1957 ◽  
Vol 19 (6) ◽  
pp. 1001-1001
Keyword(s):  
Hemolytic Anemia ◽  
Case Reports ◽  
Newborn Infants ◽  
Term Infant ◽  
Heinz Bodies ◽  
Heinz Body ◽  
Large Numbers ◽  
Complete Reversal ◽  
Staining Techniques ◽  
Supravital Staining

The association of Heinz-bodies within erythrocytes, extreme distortion of the size and shape of erythrocytes and hemolytic anemia in newborn infants, especially premature infants, has been sporadically reported in the medical literature since 1948. Heinz-bodies are thought to be either remnants of disintegrated membranes of erythocytes or abnormal products of hemoglobin metablism, and are demonstrable only by supravital staining techniques. The present study contributes two case reports and discusses the sequence of the clinical and hematologic manifestations. The first patient was a full-term infant who developed jaundice and symptoms attributable to anemia at 2 weeks of life. The second infant was prematurely born, did not develop jaundice but showed large numbers of Heinz-bodies (70%) as the anemia progressed. Both patients responded well to a single transfusion of packed blood cells, with complete reversal of the abnormal peripheral blood findings. None of the usual causes of hemolysis could be demonstrated by extensive laboratory tests. Agents such as phenylhydrazine, known to produce Heinz-bodies, could not be incriminated. The phenomenon of Heinz-body formation in infants may be more common than is apparent as the technique of demonstration is not commonly a part of the routine study of infants with evidence of hemolytic anemia. This technique is described and illustrations of erythrocytes containing Heinz-bodies are provided.

Spurious, marked leukocytosis in 2 cats with Heinz body hemolytic anemia

2020 ◽  
Vol 49 (2) ◽  
pp. 232-239
Author(s):  
Courtney E. Johnson ◽  
Davis M. Seelig ◽  
Frances M. Moore ◽  
Tammy J. Ruska ◽  
Daniel A. Heinrich
Keyword(s):  
Hemolytic Anemia ◽  
Heinz Body

Idiopathic Heinz Body Hemolytic Anemia in Newborn Infants

1989 ◽  
Vol 11 (1) ◽  
pp. 3-7 ◽  
Author(s):  
A. Ballin ◽  
E. J. Brown ◽  
A. Zipursky
Keyword(s):  
Hemolytic Anemia ◽  
Newborn Infants ◽  
Heinz Body

Heinz-body hemolytic anemia from the ingestion of crude oil: a primary toxic effect in marine birds

Science ◽  
1983 ◽  
Vol 220 (4599) ◽  
pp. 871-873 ◽  
Author(s):  
F. Leighton ◽  
D. Peakall ◽  
R. Butler
Keyword(s):  
Crude Oil ◽  
Toxic Effect ◽  
Hemolytic Anemia ◽  
Marine Birds ◽  
Heinz Body

Heinz Body Hemolytic Anemia With Eccentrocytosis From Ingestion of Chinese Chive (Allium tuberosum) and Garlic (Allium sativum) in a Dog

2005 ◽  
Vol 41 (1) ◽  
pp. 68-73 ◽  
Author(s):  
Osamu Yamato ◽  
Ei Kasai ◽  
Taro Katsura ◽  
Shinichi Takahashi ◽  
Takuji Shiota ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Hemolytic Anemia ◽  
Allium Sativum ◽  
Intact Male ◽  
Allium Tuberosum ◽  
Heinz Body ◽  
Chinese Chive

A 4-year-old, intact male miniature schnauzer was presented with anorexia. The dog had ingested some Chinese steamed dumplings 2 days before, which contained Chinese chive (Allium tuberosum) and garlic (Allium sativum). Hematological examinations revealed severe Heinz body hemolytic anemia with eccentrocytosis and an increased concentration of methemoglobin, which was thought to result from oxidative damage to erythrocytes by constituents in these Allium plants. In this case, eccentrocytosis was a hallmark finding and could be detected easily, suggesting that this hematological abnormality is useful in diagnosing Allium plant-induced hemolysis.

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